Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Achim, Lass"'
Autor:
Dominik Bulfon, Johannes Breithofer, Gernot F. Grabner, Nermeen Fawzy, Anita Pirchheim, Heimo Wolinski, Dagmar Kolb, Lennart Hartig, Martin Tischitz, Clara Zitta, Greta Bramerdorfer, Achim Lass, Ulrike Taschler, Dagmar Kratky, Peter Greimel, Robert Zimmermann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Bis(monoacylglycero)phosphate (BMP) is a major phospholipid constituent of intralumenal membranes in late endosomes/lysosomes, where it regulates the degradation and sorting of lipid cargo. Recent observations suggest that the Batten disease
Externí odkaz:
https://doaj.org/article/29ec4e2adaf241899bdcc3d74c8b6fe0
Autor:
Joshua Adekunle Babalola, Anika Stracke, Tina Loeffler, Irene Schilcher, Spyridon Sideromenos, Stefanie Flunkert, Joerg Neddens, Ake Lignell, Manuela Prokesch, Ute Panzenboeck, Herbert Strobl, Jelena Tadic, Gerd Leitinger, Achim Lass, Birgit Hutter-Paier, Gerald Hoefler
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101972- (2024)
Externí odkaz:
https://doaj.org/article/d463c6ae0e50498bb0f6926bfae42908
Autor:
Joshua Adekunle Babalola, Anika Stracke, Tina Loeffler, Irene Schilcher, Spyridon Sideromenos, Stefanie Flunkert, Joerg Neddens, Ake Lignell, Manuela Prokesch, Ute Pazenboeck, Herbert Strobl, Jelena Tadic, Gerd Leitinger, Achim Lass, Birgit Hutter-Paier, Gerald Hoefler
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101959- (2024)
Objectives: Aggregation and misfolding of amyloid beta (Aβ) and tau proteins, suggested to arise from post-translational modification processes, are thought to be the main cause of Alzheimer's disease (AD). Additionally, a plethora of evidence exist
Externí odkaz:
https://doaj.org/article/adc5cdc60dae4aeea2d8de4c6bfa0ca8
Autor:
Julia S. Steinhoff, Carina Wagner, Ulrike Taschler, Sascha Wulff, Marie F. Kiefer, Konstantin M. Petricek, Sylvia J. Wowro, Moritz Oster, Roberto E. Flores, Na Yang, Chen Li, Yueming Meng, Manuela Sommerfeld, Stefan Weger, Andrea Henze, Jens Raila, Achim Lass, Michael Schupp
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 10, Pp 100268- (2022)
Hepatocytes secrete retinol-binding protein 4 (RBP4) into circulation, thereby mobilizing vitamin A from the liver to provide retinol for extrahepatic tissues. Obesity and insulin resistance are associated with elevated RBP4 levels in the blood. Howe
Externí odkaz:
https://doaj.org/article/3e03abb6a7e44542a7029ef73356845c
Autor:
Laura Pajed, Ulrike Taschler, Anna Tilp, Peter Hofer, Petra Kotzbeck, Stephanie Kolleritsch, Franz P. W. Radner, Isabella Pototschnig, Carina Wagner, Margarita Schratter, Sandra Eder, Sabrina Huetter, Renate Schreiber, Guenter Haemmerle, Thomas O. Eichmann, Martina Schweiger, Gerald Hoefler, Erin E. Kershaw, Achim Lass, Gabriele Schoiswohl
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Pajed et al. investigate the role of adipocyte hormone-sensitive lipase (HSL) in whole body energy homeostasis. They show that adipocyte-specific HSL Knockout (AHKO) mice fed high fat diet develop fatty liver. Interestingly, this phenotype reverses i
Externí odkaz:
https://doaj.org/article/489219dde80844a090448c922d5f0fbd
Autor:
Carina Wagner, Victoria Hois, Annalena Eggeling, Lisa-Maria Pusch, Laura Pajed, Patrick Starlinger, Thierry Claudel, Michael Trauner, Robert Zimmermann, Ulrike Taschler, Achim Lass
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 3, Pp 100173- (2022)
Large quantities of vitamin A are stored as retinyl esters (REs) in specialized liver cells, the hepatic stellate cells (HSCs). To date, the enzymes controlling RE degradation in HSCs are poorly understood. In this study, we identified KIAA1363 (also
Externí odkaz:
https://doaj.org/article/9e072aff898e4609a2c37508d808e9c1
Autor:
Gernot F. Grabner, Nermeen Fawzy, Renate Schreiber, Lisa M. Pusch, Dominik Bulfon, Harald Koefeler, Thomas O. Eichmann, Achim Lass, Martina Schweiger, Gunther Marsche, Gabriele Schoiswohl, Ulrike Taschler, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 995-1003 (2020)
Bis(monoacylglycero)phosphate (BMP), also known as lysobisphosphatidic acid, is a phospholipid that promotes lipid sorting in late endosomes/lysosomes by activating lipid hydrolases and lipid transfer proteins. Changes in the cellular BMP content the
Externí odkaz:
https://doaj.org/article/2be18605ca1f457e8139b8198ab5f48a
Comparative transcriptomics reveals candidate carotenoid color genes in an East African cichlid fish
Autor:
Ehsan Pashay Ahi, Laurène A. Lecaudey, Angelika Ziegelbecker, Oliver Steiner, Ronald Glabonjat, Walter Goessler, Victoria Hois, Carina Wagner, Achim Lass, Kristina M. Sefc
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Carotenoids contribute significantly to animal body coloration, including the spectacular color pattern diversity among fishes. Fish, as other animals, derive carotenoids from their diet. Following uptake, transport and metabolic
Externí odkaz:
https://doaj.org/article/c68dd80fa44f4dca9877ece6cfbf978a
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1015 (2022)
The α/β-Hydrolase domain-containing protein 5 (ABHD5; also known as comparative gene identification-58, or CGI-58) is the causative gene of the Chanarin-Dorfman syndrome (CDS), a disorder mainly characterized by systemic triacylglycerol accumulatio
Externí odkaz:
https://doaj.org/article/3b11d410a9e9417f913aadc44683e55c
Autor:
Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 1020-1031 (2019)
Bis(monoacylglycerol)phosphate (BMP) is a phospholipid that is crucial for lipid degradation and sorting in acidic organelles. Genetic and drug-induced lysosomal storage disorders (LSDs) are associated with increased BMP concentrations in tissues and
Externí odkaz:
https://doaj.org/article/6811fbb03319497cbbdc699b457cff47