Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Achilleas D. Theocharis"'
Autor:
Virginia D. Dimaki, Efstathia Stamopoulou, Dimitra Manou, Achilleas D. Theocharis, Manolis A. Fousteris, Fotini N. Lamari
Publikováno v:
ACS Omega, Vol 9, Iss 41, Pp 42253-42260 (2024)
Externí odkaz:
https://doaj.org/article/ee34f2dfd3c049ac992115cfe69eee51
Autor:
Dimitra Manou, Maria-Angeliki Golfinopoulou, Sara Naif D. Alharbi, Hind A. Alghamdi, Fatimah Mohammed Alzahrani, Achilleas D. Theocharis
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 461 (2024)
Serglycin (SRGN) is a pro-tumorigenic proteoglycan expressed and secreted by various aggressive tumors including glioblastoma (GBM). In our study, we investigated the interplay and biological outcomes of SRGN with TGFβRI, CXCR-2 and inflammatory med
Externí odkaz:
https://doaj.org/article/206e2141810443c09132224ff6f19bdb
Autor:
Marta Tellez-Gabriel, Xavier Tekpli, Trine M. Reine, Beate Hegge, Stephanie R. Nielsen, Meng Chen, Line Moi, Lisa Svartdal Normann, Lill-Tove R. Busund, George A. Calin, Gunhild M. Mælandsmo, Maria Perander, Achilleas D. Theocharis, Svein O. Kolset, Erik Knutsen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Serglycin is a proteoglycan highly expressed by immune cells, in which its functions are linked to storage, secretion, transport, and protection of chemokines, proteases, histamine, growth factors, and other bioactive molecules. In recent years, it h
Externí odkaz:
https://doaj.org/article/920c9876187840389df53c28d18f306b
Autor:
Sophia Grigoropoulou, Dimitra Manou, Antonia I. Antoniou, Artemis Tsirogianni, Carlo Siciliano, Achilleas D. Theocharis, Constantinos M. Athanassopoulos
Publikováno v:
Molecules, Vol 27, Iss 11, p 3623 (2022)
Dehydroabietic Acid (DHA, 1) derivatives are known for their antiproliferative properties, among others. In the context of this work, DHA was initially modified to two key intermediates bearing a C18 methyl ester, a phenol moiety at C12, and an acety
Externí odkaz:
https://doaj.org/article/bcd295e782a1488d8e95baca08aa073f
Publikováno v:
Matrix Biology Plus, Vol 6, Iss , Pp 100038- (2020)
The extracellular matrix is engaged in an ever-evolving and elegant ballet of dynamic reciprocity that directly and bi-directionally regulates cell behavior. Homeostatic and pathophysiological changes in cell-matrix signaling cascades manifest as com
Externí odkaz:
https://doaj.org/article/61e996e4d73b400594cfa449992a57ec
Autor:
Dimitra Manou, Panagiotis Bouris, Dimitris Kletsas, Martin Götte, Burkhard Greve, Aristidis Moustakas, Nikos K. Karamanos, Achilleas D. Theocharis
Publikováno v:
Matrix Biology Plus, Vol 6, Iss , Pp 100033- (2020)
Despite the functional role of serglycin as an intracellular proteoglycan, a variety of malignant cells depends on its expression and constitutive secretion to advance their aggressive behavior. Serglycin arose to be a biomarker for glioblastoma, whi
Externí odkaz:
https://doaj.org/article/e12b4dc2a8e34083aa864c7f9a4f1f74
Autor:
Angeliki eKorpetinou, Spyros S Skandalis, Vassiliki T Labropoulou, Gianna eSmirlaki, Argyrios eNoulas, Nikos K. Karamanos, ACHILLEAS D. THEOCHARIS
Publikováno v:
Frontiers in Oncology, Vol 3 (2014)
Serglycin has been initially characterized as an intracellular proteoglycan expressed by hematopoietic cells. All inflammatory cells highly synthesize serglycin and store it in granules, where it interacts with numerous inflammatory mediators, such a
Externí odkaz:
https://doaj.org/article/bdc113103e9e433c981a5a2ca3b107b4
Enhancement of mesenchymal stem cells’ chondrogenic potential by type II collagen-based bioscaffolds
Autor:
Zoi Piperigkou, Dimitra Bainantzou, Nadia Makri, Eleni Papachristou, Aglaia Mantsou, Theodora Choli-Papadopoulou, Achilleas D. Theocharis, Nikos K. Karamanos
Publikováno v:
Molecular Biology Reports. 50:5125-5135
Background Osteoarthritis (OA) is a common degenerative chronic disease accounting for physical pain, tissue stiffness and mobility restriction. Current therapeutic approaches fail to prevent the progression of the disease considering the limited kno
Autor:
Vaios D. Fytsilis, Dimitra Manou, Achilleas D. Theocharis, Spyros S. Skandalis, Demitrios Vynios
IntroductionTriple negative breast cancer is characterized by rapid growth and dissemination. Epithelial to mesenchymal transition facilitates tumor progression and cellular stemness status. Statins are affordable medicines with traditional action as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12c19bc49c5aa5df53a270b59bb4b34a
https://doi.org/10.21203/rs.3.rs-1886748/v1
https://doi.org/10.21203/rs.3.rs-1886748/v1
Autor:
Zoi Piperigkou, Dimitra Manou, Dimitra Bainantzou, Vasiliki Zolota, Εfthymia Papakonstantinou, Achilleas D. Theocharis, Nikos K. Karamanos
Publikováno v:
The Extracellular Matrix and the Tumor Microenvironment ISBN: 9783030997076
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8fddd3f8d9d78803dd7b8d19c3849a
https://doi.org/10.1007/978-3-030-99708-3_16
https://doi.org/10.1007/978-3-030-99708-3_16