Zobrazeno 1 - 10
of 8 392
pro vyhledávání: '"Ache"'
Autor:
Sunil Shewale, Vaishali Undale, Vrushali Bhalchim, Mohini Kuchekar, Bhagyashri Warude, Mayur Mali
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract The rising incidence of neurodegenerative diseases represents a significant global health concern. The prognosis for such diseases is often unfavorable, and patients require supportive treatment to manage their condition effectively. The pre
Externí odkaz:
https://doaj.org/article/6c7c0025cba047f999c8ab42e1f031c9
Autor:
Shoaib Khan, Tayyiaba Iqbal, Muhammad Bilal Khan, Rafaqat Hussain, Yousaf Khan, Hany W. Darwish
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-18 (2024)
Abstract As a springboard to explore novel potent inhibitors of cholinesterase enzymes (AChE and BChE) responsible for causing Alzheimer disorder, the current study was conducted to synthesize pyrrole derived triazole based Schiff base scaffolds by f
Externí odkaz:
https://doaj.org/article/a3907f7f155246f9bfd1699712108849
Autor:
Mehmet Resit Taysı
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cadmium contamination in aquatic environments poses severe risks to aquatic organisms, particularly fish, where cadmium accumulation in tissues can lead to compromised organ functionality and reproductive issues. The present study aimed to a
Externí odkaz:
https://doaj.org/article/bcd4a590259641a3bf328a2368f529dd
Publikováno v:
Electronic Journal of Biotechnology, Vol 72, Iss , Pp 12-19 (2024)
Background: Alzheimer’s disease is a neurodegenerative disease that has no cure. The drugs used to treat Alzheimer’s disease are based on the inhibition of the enzyme acetylcholinesterase (AChE). In this sense, marine fungal metabolites represent
Externí odkaz:
https://doaj.org/article/ab641c4610fe4c95ba12e55ade38277e
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 3, Pp 1238-1255 (2024)
This study investigates using KOH-activated coffee grounds (KACGs) as an effective adsorbent for removing organophosphorus xenobiotics malathion and chlorpyrifos from water. Malathion and chlorpyrifos, widely used as pesticides, pose significant heal
Externí odkaz:
https://doaj.org/article/189f3014ccf84d40b690fb5e1dacd650
Autor:
Ullah Imran, Neder Reinhard B., Ahmad Mushtaq, Khan Abdul Qadir, Rauf Abdur, Alshammari Abdulrahman, Albekairi Norah Abdullah
Publikováno v:
Green Processing and Synthesis, Vol 13, Iss 1, Pp 76-81 (2024)
Externí odkaz:
https://doaj.org/article/93eea10ad3714ece943931dccba95c0d
Publikováno v:
Pharmaceutical and Biomedical Research, Vol 10, Iss 3, Pp 191-202 (2024)
Background: In the spectrum of neurodegenerative conditions, Alzheimer disease (AD) stands out as the predominant contributor to dementia and behavioral alterations. Cholinesterase inhibitors (ChE-Is) represent the primary pharmaceutical category cur
Externí odkaz:
https://doaj.org/article/20bc1318531044698c44fb136da59777
Publikováno v:
Chemical and Biological Technologies in Agriculture, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract Background Neonicotinoids are widespread insecticides because of their potent effects against aphids and other piercing-sucking insects in addition to having high selectivity toward insects rather than vertebrates. However, they affect sever
Externí odkaz:
https://doaj.org/article/0d8cee346ca14ac1bf975fa9a643ed26
Autor:
Mohammed Salah Ayoup, Mariam Ghanem, Hamida Abdel-Hamid, Marwa M. Abu-Serie, Aliaa Masoud, Doaa A. Ghareeb, Mohammed B. Hawsawi, Amr Sonousi, Asmaa E. Kassab
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-15 (2024)
Abstract A series of new 1,2,4-oxadiazole-based derivatives were synthesized and evaluated for their anti-AD potential. The results revealed that eleven compounds (1b, 2a-c, 3b, 4a-c, and 5a-c) exhibited excellent inhibitory potential against AChE, w
Externí odkaz:
https://doaj.org/article/dc68b8e4e3bd464b9dddc323540f7db5
Autor:
Šobot Ana Valenta, Janić Marijana, Popović Iva, Lazarević-Pašti Tamara, Momić Tatjana, Krstić Aleksandar, Tričković Jelena Filipović
Publikováno v:
Arhiv za Higijenu Rada i Toksikologiju, Vol 75, Iss 2, Pp 137-146 (2024)
Traditional medicine has used sage (Salvia officinalis L.) preparations for centuries to prevent and treat various inflammatory and oxidative stress-induced conditions. The aim of this in vitro study was to determine the bioactive properties of a sag
Externí odkaz:
https://doaj.org/article/04576acc506b4cbfb9b613e9ec76f9ef