Výsledky vyhledávání - "Achchuthan Shanmugasundram"

Akademický článek

TriTrypDB: An integrated functional genomics resource for kinetoplastida.

Autor: Achchuthan Shanmugasundram, David Starns, Ulrike Böhme, Beatrice Amos, Paul A Wilkinson, Omar S Harb, Susanne Warrenfeltz, Jessica C Kissinger, Mary Ann McDowell, David S Roos, Kathryn Crouch, Andrew R Jones

Publikováno v: PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011058 (2023)

Parasitic diseases caused by kinetoplastid parasites are a burden to public health throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb.org) is a free online resource for data mining of genomic and functional data fr

Externí odkaz: https://doaj.org/article/376d108ca2a94805950a5651f8c3e5c9

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Akademický článek

FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes

Autor: Evelina Y. Basenko, Jane A. Pulman, Achchuthan Shanmugasundram, Omar S. Harb, Kathryn Crouch, David Starns, Susanne Warrenfeltz, Cristina Aurrecoechea, Christian J. Stoeckert, Jessica C. Kissinger, David S. Roos, Christiane Hertz-Fowler

Publikováno v: Journal of Fungi, Vol 4, Iss 1, p 39 (2018)

FungiDB (fungidb.org) is a free online resource for data mining and functional genomics analysis for fungal and oomycete species. FungiDB is part of the Eukaryotic Pathogen Genomics Database Resource (EuPathDB, eupathdb.org) platform that integrates

Externí odkaz: https://doaj.org/article/37533114ee394b0fa0c18d7c4b815bd5

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Akademický článek

ERK1/2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytes.

Autor: Andrew K Marshall, Oliver P T Barrett, Timothy E Cullingford, Achchuthan Shanmugasundram, Peter H Sugden, Angela Clerk

Publikováno v: PLoS ONE, Vol 5, Iss 4, p e10027 (2010)

Cardiomyocyte hypertrophy is associated with changes in gene expression. Extracellular signal-regulated kinases 1/2 (ERK1/2) and RhoA [activated by hypertrophic agonists (e.g. endothelin-1)] regulate gene expression and are implicated in the response

Externí odkaz: https://doaj.org/article/a5f889d6a8db46e181196577e51151c9

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VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

Autor: Jamie Long, Sheena Shah Tomko, Susanne Warrenfeltz, Kristopher Lamoureux, Mary Ann McDowell, Brett Fox, Ulrike Böhme, Mark J Hickman, Steve Fisher, David Starns, George K. Christophides, Ana Barreto, Ann Sizemore Blevins, David S. Roos, Daniel Lawson, Lin Xu, Jie Zheng, John Judkins, Kristina Davis, Ryan Doherty, Jeremy D. DeBarry, Jaroslaw Nabrzyski, Lahcen I. Campbell, Samuel S. C. Rund, Evelina Y. Basenko, Beatrice Amos, Dave Falke, Mikkel B. Christensen, Stephanie Wever Schulman, Robert Wieck, Michael J. Dunn, Gareth Maslen, Mark X. Caddick, Haiming Wang, Robert Belnap, Wei Li, Christiane Hertz-Fowler, Achchuthan Shanmugasundram, Kathryn Crouch, Sarah A. Kelly, Wojciech Bażant, Sufen Hu, Bindu Gajria, Christian J. Stoeckert, Elizabeth Harper, Jay C. Humphrey, Jessica C. Kissinger, Paul A Wilkinson, Yikun Duan, Brian P. Brunk, John Brestelli, Matthieu Barba, Robert M. MacCallum, Kallie Lies, Omar S. Harb, Vasily Sitnik, Paul Flicek, Andrew M. Jones, Disha Lodha, Gloria I. Giraldo-Calderón, John Iodice, Danielle Callan, Drew Spruill, Cristina Aurrecoechea, Connor Howington, Dae Kun Kwon

Publikováno v: NUCLEIC ACIDS RESEARCH
Nucleic Acids Research
Amos, B, Aurrecoechea, C, Barba, M, Barreto, A, Basenko, E Y, Bażant, W, Belnap, R, Blevins, A S, Böhme, U, Brestelli, J, Brunk, B P, Caddick, M, Callan, D, Campbell, L, Christensen, M B, Christophides, G K, Crouch, K, Davis, K, Debarry, J, Doherty, R, Duan, Y, Dunn, M, Falke, D, Fisher, S, Flicek, P, Fox, B, Gajria, B, Giraldo-Calderón, G I, Harb, O S, Harper, E, Hertz-Fowler, C, Hickman, M J, Howington, C, Hu, S, Humphrey, J, Iodice, J, Jones, A, Judkins, J, Kelly, S A, Kissinger, J C, Kwon, D K, Lamoureux, K, Lawson, D, Li, W, Lies, K, Lodha, D, Long, J, MacCallum, R M, Maslen, G, McDowell, M A, Nabrzyski, J, Roos, D S, Rund, S S C, Schulman, S W, Shanmugasundram, A, Sitnik, V, Spruill, D, Starns, D, Stoeckert, C J, Tomko, S S, Wang, H, Warrenfeltz, S, Wieck, R, Wilkinson, P A, Xu, L & Zheng, J 2022, ' VEuPathDB : The eukaryotic pathogen, vector and host bioinformatics resource center ', Nucleic Acids Research, vol. 50, no. D1 . https://doi.org/10.1093/nar/gkab929

The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB, https://veupathdb.org) represents the 2019 merger of VectorBase with the EuPathDB projects. As a Bioinformatics Resource Center funded by the National Institutes of Health, wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e18d51670b3121a959cb0e4c2478f0b
http://livrepository.liverpool.ac.uk/3142948/1/gkab929.pdf

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Genome Assemblies across the Diverse Evolutionary Spectrum of Leishmania Protozoan Parasites

Autor: Gowthaman Ramasamy, Chad Tomlinson, Natalia S. Akopyants, Sascha Steinbiss, Fatima Silva-Franco, Peter J. Myler, Deborah E. Dobson, Lon-Fye Lye, Wesley C. Warren, Richard K. Wilson, Christiane Hertz-Fowler, Stephen M. Beverley, Achchuthan Shanmugasundram

Publikováno v: Microbiology Resource Announcements

We report the high-quality draft assemblies and gene annotations for 13 species and/or strains of the protozoan parasite genera Leishmania , Endotrypanum , and Crithidia , which span the phylogenetic diversity of the subfamily Leishmaniinae within th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ded57804e79d6367ab4e4e45f2bb46
https://doi.org/10.1128/mra.00545-21

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‘Students-as-partners’ scheme enhances postgraduate students’ employability skills while addressing gaps in bioinformatics education

Autor: Achchuthan Shanmugasundram, Anshul Gupta, Luke Tregilgas, Anjeet Jhutty, Luciane V. Mello, Fatima A. Makki, Gwendolyn Cowley

Publikováno v: Higher Education Pedagogies
Higher Education Pedagogies, Vol 2, Iss 1, Pp 43-57 (2017)

Teaching bioinformatics is a longstanding challenge for educators who need to demonstrate to students how skills developed in the classroom may be applied to real world research. This study employed an action research methodology which utilised stude

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8e1dd4146a1c8dde50f886f7fa4555
http://europepmc.org/articles/PMC5632996

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Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity

Publikováno v: Current Biology-CB
Current Biology-CB, 2019, 29 (10), pp.1712-1720. ⟨10.1016/j.cub.2019.04.020⟩
Current Biology
Current Biology-CB, Elsevier, 2019, 29 (10), pp.1712-1720. ⟨10.1016/j.cub.2019.04.020⟩
CURRENT BIOLOGY
1720.e7

Summary Some species responded successfully to prehistoric changes in climate [1, 2], while others failed to adapt and became extinct [3]. The factors that determine successful climate adaptation remain poorly understood. We constructed a reference g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb051cb6d1b545251971e2fdd20b208
https://doi.org/10.1016/j.cub.2019.04.020

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EuPathDB: the eukaryotic pathogen genomics database resource

Publikováno v: Nucleic Acids Research
NUCLEIC ACIDS RESEARCH

The Eukaryotic Pathogen Genomics Database Resource (EuPathDB, http://eupathdb.org) is a collection of databases covering 170+ eukaryotic pathogens (protists & fungi), along with relevant free-living and non-pathogenic species, and select pathogen hos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae70c2ac381c67f957710bd9907ab126

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EuPathDB: The Eukaryotic Pathogen Genomics Database Resource

Autor: Fatima Silva-Franco, David S. Roos, Achchuthan Shanmugasundram, Kathryn Crouch, Susanne Warrenfeltz, Evelina Y. Basenko, Jessica C. Kissinger, Omar S. Harb

Publikováno v: Methods in Molecular Biology ISBN: 9781493977369

Fighting infections and developing novel drugs and vaccines requires advanced knowledge of pathogen's biology. Readily accessible genomic, functional genomic, and population data aids biological and translational discovery. The Eukaryotic Pathogen Da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccba3ba8a3a8f300bc9320da2ab348f7
https://pubmed.ncbi.nlm.nih.gov/29761457

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