Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Achala N. D. Punchi Hewage"'
Autor:
Achala N D Punchi Hewage, Joel K. Annor-Gyamfi, Huili Yao, Kevin P. Battaile, Richard A. Bunce, Scott Lovell, Kevin Meraz, Anabel Soldano, Mario Rivera
Publikováno v:
ACS Infectious Diseases. 7:123-140
Bacteria depend on a well-regulated iron homeostasis to survive adverse environments. A key component of the iron homeostasis machinery is the compartmentalization of Fe3+ in bacterioferritin and its subsequent mobilization as Fe2+ to satisfy metabol
Autor:
Achala N. D. Punchi Hewage, Huili Yao, Baskar Nammalwar, Krishna Kumar Gnanasekaran, Scott Lovell, Richard A. Bunce, Kate Eshelman, Sahishna M. Phaniraj, Molly M. Lee, Blake R. Peterson, Kevin P. Battaile, Allen B. Reitz, Mario Rivera
Publikováno v:
Journal of the American Chemical Society. 141:8171-8184
[Image: see text] The iron storage protein bacterioferritin (BfrB) is central to bacterial iron homeostasis. The mobilization of iron from BfrB, which requires binding by a cognate ferredoxin (Bfd), is essential to the regulation of cytosolic iron le
Autor:
Anabel, Soldano, Huili, Yao, Achala N D, Punchi Hewage, Kevin, Meraz, Joel K, Annor-Gyamfi, Richard A, Bunce, Kevin P, Battaile, Scott, Lovell, Mario, Rivera
Publikováno v:
ACS Infectious Diseases
Bacteria depend on a well-regulated iron homeostasis to survive adverse environments. A key component of the iron homeostasis machinery is the compartmentalization of Fe3+ in bacterioferritin and its subsequent mobilization as Fe2+ to satisfy metabol
Autor:
Achala N D Punchi Hewage, Mario Rivera, Leo Fontenot, Fabrizio Donnarumma, Jessie J Guidry, Thomas K. Weldeghiorghis, Anil K. Mehta
Publikováno v:
Pathogens
Volume 9
Issue 12
Volume 9
Issue 12
Iron homeostasis offers a significant bacterial vulnerability because pathogens obtain essential iron from their mammalian hosts, but host-defenses maintain vanishingly low levels of free iron. Although pathogens have evolved mechanisms to procure ho
Autor:
Huili Yao, K. Eshelman, Mario Rivera, Jacqueline J. Deay, Josephine R. Chandler, Achala N D Punchi Hewage
Publikováno v:
Metallomics. 9:646-659
Iron is an essential nutrient for bacteria but the reactivity of Fe2+ and the insolubility of Fe3+ present significant challenges to bacterial cells. Iron storage proteins contribute to ameliorating these challenges by oxidizing Fe2+ using O2 and H2O