Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Achal Pashine"'
Autor:
Stefan Seeber, Francesca Ros, Irmgard Thorey, Georg Tiefenthaler, Klaus Kaluza, Valeria Lifke, Jens André Alexander Fischer, Stefan Klostermann, Josef Endl, Erhard Kopetzki, Achal Pashine, Basile Siewe, Brigitte Kaluza, Josef Platzer, Sonja Offner
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://doaj.org/article/121e8ae00e8c4eaa9913c08d88a77bdd
Autor:
Stanley R. Krystek, Robert F. Graziano, Richard Y.-C. Huang, Nathan J Felix, Mohan Srinivasan, Guodong Chen, Achal Pashine
Publikováno v:
mAbs. 10:95-103
TL1A, a tumor necrosis factor-like cytokine, is a ligand for the death domain receptor DR3. TL1A, upon binding to DR3, can stimulate lymphocytes and trigger secretion of proinflammatory cytokines. Therefore, blockade of TL1A/DR3 interaction may be a
Autor:
Kevin Peese, Joseph E. Carpenter, James H. Cook, Gillis Eric P, Catherine A. Bolger, Peter S. Dragovich, T. G. Murali Dhar, Achal Pashine, J. Robert Merritt
Publikováno v:
2018 Medicinal Chemistry Reviews ISBN: 9780996293266
2018 Medicinal Chemistry Reviews
2018 Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::014e3316d1824afef46c3b6e89c3031b
https://doi.org/10.29200/acsmedchemrev-v53.ch29
https://doi.org/10.29200/acsmedchemrev-v53.ch29
Autor:
William Mallet, Achal Pashine, J. Robert Merritt, Peter S. Dragovich, Catherine A. Bolger, T. G. Murali Dhar, Kevin Peese
Publikováno v:
2017 Medicinal Chemistry Reviews ISBN: 9780996293242
2017 Medicinal Chemistry Reviews
2017 Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f007e6facab6cf0e5b3e80d263230b
https://doi.org/10.29200/acsmedchemrev-v52.ch28
https://doi.org/10.29200/acsmedchemrev-v52.ch28
Autor:
Kevin Peese, Ricardo Garcia, Joanne J. Bronson, Bruce A. Ellsworth, Achal Pashine, J. Robert Merritt, Dhar T G Murali, Franck J. Duclos
Publikováno v:
Medicinal Chemistry Reviews ISBN: 9780996293235
Medicinal Chemistry Reviews
Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7feec779ca54a1415606ee0693b51b97
https://doi.org/10.29200/acsmedchemrev-v51.ch25
https://doi.org/10.29200/acsmedchemrev-v51.ch25
Autor:
Julie DeMartino, Ronald J. Hill, Jay S. Fine, Alison O'Mahony, Jennifer Postelnek, Cheng Liao, Dinesh Srinivasan, Michael Bradshaw, Anita Levin, Daigen Xu, Yong Kim, Satwant K. Narula, Achal Pashine, Dong-Qing Hu, John Woods, Jonathan Hsu, Minh Diem Vu, Yan Lou, Jun Zhang, Timothy D. Owens
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 341:90-103
Genetic mutation and pharmacological inhibition of Bruton9s tyrosine kinase (Btk) both have been shown to prevent the development of collagen-induced arthritis (CIA) in mice, providing a rationale for the development of Btk inhibitors for treating rh
Autor:
Bruce A. Ellsworth, Joanne J. Bronson, Amelia Black, J. Robert Merritt, Dhar T G Murali, Kevin Peese, Achal Pashine
Publikováno v:
Medicinal Chemistry Reviews ISBN: 9780996293211
Medicinal Chemistry Reviews
Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e898e1967b2e1d29c7a02f1c1ded1c
https://doi.org/10.29200/acsmedchemrev-v50.ch19
https://doi.org/10.29200/acsmedchemrev-v50.ch19
Autor:
Elizabeth D. Mellins, Timo Burster, Tara M. C. Hornell, James J. Harding, Claudia Macaubas, Maria Teresa Ochoa, Andrew W. Lee, Frode L. Jahnsen, Achal Pashine, Robert L. Modlin
Publikováno v:
The Journal of Immunology. 176:3536-3547
Expression of HLA-DO (DO) in cells that express HLA-DM (DM) results in an altered repertoire of MHC class II/peptide complexes, indicating that DO modulates DM function. Human and murine B cells and thymic epithelial cells express DO, while monocytes
Autor:
Dennis M. Zaller, Elizabeth D. Mellins, Wendy Liu, Michael P. Belmares, Achal Pashine, Robert C. Doebele, Robert Busch
Publikováno v:
University of Roehampton-PURE
During maturation of MHC II molecules, newly synthesized and assembled complexes of MHC II αβ dimers with invariant chain (Ii) are targeted to endosomes, where Ii is proteolyzed, leaving remnant class II-associated Ii peptides (CLIP) in the MHC II
Publikováno v:
The Journal of Immunology. 169:2545-2552
Clearance of facultative intracellular pathogens such as Salmonella requires IFN-γ from CD4 T cells. Mechanisms linking intracellular pathogen recognition with induction of IFN-γ-producing T cells are still poorly understood. We show in this study