Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer.

Autor: Ganguli P; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Basanta CC; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Acha-Sagredo A; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Misetic H; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Armero M; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Mendez A; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Zahra A; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK., Devonshire G; Early Cancer Institute, Hutchison Research Centre, University of Cambridge, Cambridge, UK., Kelly G; Bioinformatics & Biostatistics STP, The Francis Crick Institute, London, UK., Freeman A; Early Cancer Institute, Hutchison Research Centre, University of Cambridge, Cambridge, UK., Green M; Experimental Histopathology STP, The Francis Crick Institute, London, UK., Nye E; Experimental Histopathology STP, The Francis Crick Institute, London, UK., Bichisecchi A; Epithelial Stem Cell Biology & Regenerative Medicine Laboratory, The Francis Crick Institute, London, UK.; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, London, UK., Bonfanti P; Epithelial Stem Cell Biology & Regenerative Medicine Laboratory, The Francis Crick Institute, London, UK.; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, London, UK., Rodriguez-Justo M; Department of Pathology, UCL Cancer Institute, London, UK., Spencer J; School of Immunology and Microbial Sciences, King's College London, London, UK., Fitzgerald RC; Early Cancer Institute, Hutchison Research Centre, University of Cambridge, Cambridge, UK., Ciccarelli FD; Cancer Systems Biology Laboratory, The Francis Crick Institute, London, UK. f.ciccarelli@qmul.ac.uk.; Barts Cancer Institute - Centre for Cancer Evolution, Queen Mary University of London, London, UK. f.ciccarelli@qmul.ac.uk.

Publikováno v: Nature cancer [Nat Cancer] 2025 Jan 03. Date of Electronic Publication: 2025 Jan 03.

A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution

Autor: Michele Bortolomeazzi, Lucia Montorsi, Damjan Temelkovski, Mohamed Reda Keddar, Amelia Acha-Sagredo, Michael J. Pitcher, Gianluca Basso, Luigi Laghi, Manuel Rodriguez-Justo, Jo Spencer, Francesca D. Ciccarelli

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Current high-dimension imaging data analysis methods are technology-specific and require multiple tools, restricting analytical scalability and result reproducibility. Here the authors present SIMPLI, a software that overcomes these limitations for s

Externí odkaz: https://doaj.org/article/1fa5562be7814b96821061d920d46143

Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts

Autor: Bortolomeazzi, Michele, Keddar, Mohamed Reda, Montorsi, Lucia, Acha-Sagredo, Amelia, Benedetti, Lorena, Temelkovski, Damjan, Choi, Subin, Petrov, Nedyalko, Todd, Katrina, Wai, Patty, Kohl, Johannes, Denner, Tamara, Nye, Emma, Goldstone, Robert, Ward, Sophia, Wilson, Gareth A., Al Bakir, Maise, Swanton, Charles, John, Susan, Miles, James, Larijani, Banafshe, Kunene, Victoria, Fontana, Elisa, Arkenau, Hendrik-Tobias, Parker, Peter J., Rodriguez-Justo, Manuel, Shiu, Kai-Keen, Spencer, Jo, Ciccarelli, Francesca D.

Publikováno v: In Gastroenterology October 2021 161(4):1179-1193

Oral Candida colonization in patients with chronic periodontitis. Is there any relationship?

Autor: De-La-Torre, Janire, Quindós, Guillermo, Marcos-Arias, Cristina, Marichalar-Mendia, Xabier, Gainza, María Luisa, Eraso, Elena, Acha-Sagredo, Amelia, Aguirre-Urizar, José Manuel

Publikováno v: In Revista Iberoamericana de Micologia July-September 2018 35(3):134-139

Development and validation of molecular methodologies to assess PALB2 expression in sporadic breast cancer

Autor: Poumpouridou, Nikoleta, Acha-Sagredo, Amelia, Goutas, Nikolaos, Vlachodimitropoulos, Dimitrios, Chatziioannidou, Ioanna, Lianidou, Evi, Liloglou, Triantafyllos, Kroupis, Christos

Publikováno v: In Clinical Biochemistry February 2016 49(3):253-259