Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting.

Autor: Wright BL; Department of Medicine, Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Ariz; Division of Allergy and Immunology, Phoenix Children's Hospital, Phoenix, Ariz. Electronic address: wright.benjamin@mayo.edu., Abonia JP; Department of Pediatrics, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio., Abud EM; Division of Allergy, Asthma, and Immunology, Scripps Clinic, San Diego, Calif; Division of Allergy and Immunology, University of California, San Diego, Rady Children's Hospital, San Diego, Calif., Aceves SS; Division of Allergy and Immunology, University of California, San Diego, Rady Children's Hospital, San Diego, Calif., Ackerman SJ; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, Ill., Braskett M; Department of Pediatrics, Division of Clinical Immunology and Allergy, Children's Hospital Los Angeles, Keck School of Medicine at University of Southern California, Los Angeles, Calif., Chang JW; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Mich., Chehade M; Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, NY., Constantine GM; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md., Davis CM; Department of Pediatrics, Division of Immunology, Allergy, and Retrovirology, Baylor College of Medicine and Texas Children's Hospital, Houston, Tex., Dellon ES; Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC., Doyle AD; Department of Medicine, Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Ariz., Durban R; Carolina Asthma and Allergy Center, Charlotte, NC., Hill DA; Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa., Jensen ET; Departments of Epidemiology and Prevention and Internal Medicine, Gastroenterology Section, Wake Forest University School of Medicine, Winston-Salem, NC., Kewalramani A; Department of Pediatrics, Division of Pulmonology/Allergy, University of Maryland School of Medicine, Baltimore, Md., Khoury P; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md., Klion AD; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md., Kottyan L; Department of Pediatrics, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio., Kuang FL; Division of Allergy and Immunology, Northwestern Feinberg School of Medicine, Chicago, Ill., McGowan EC; Departments of Medicine and Pediatrics, Division of Allergy and Clinical Immunology, University of Virginia, Charlottesville, Va., Ruffner MA; Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa., Spencer LA; Department of Pediatrics, Section of Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, Colo., Spergel JM; Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa., Uchida AM; Division of Gastroenterology, Hepatology & Nutrition, University of Utah, Salt Lake City, Utah., Wechsler JB; Department of Pediatrics, Division of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill., Pesek RD; Division of Allergy and Immunology, Arkansas Children's Hospital, and the University of Arkansas for Medical Sciences, Little Rock, Ark.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 Oct; Vol. 154 (4), pp. 882-892. Date of Electronic Publication: 2024 Aug 05.

Losartan Treatment Reduces Esophageal Eosinophilic Inflammation in a Subset of Eosinophilic Esophagitis.

Autor: Abonia JP; Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio., Rudman Spergel AK; Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, Md., Hirano I; Division of Gastroenterology and Hepatology, Northwestern University, Feinberg School of Medicine, Chicago, Ill., Shoda T; Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio., Zhang X; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Martin LJ; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Mukkada VA; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Putnam PE; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Blacklidge M; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Neilson D; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Collins MH; Division of Pathology and Laboratory Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio., Yang GY; Division of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Ill., Capocelli KE; Division of Pathology, Children's Hospital Colorado, Aurora, Colo., Foote H; Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio., Eby M; Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio., Dong S; Division of Allergy Immunology, Rady Children's Hospital, University of California, San Diego, San Diego, Calif., Aceves SS; Division of Allergy Immunology, Rady Children's Hospital, University of California, San Diego, San Diego, Calif. Electronic address: saceves@ucsd.edu., Rothenberg ME; Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Publikováno v: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2024 Sep; Vol. 12 (9), pp. 2427-2438.e3. Date of Electronic Publication: 2024 Jul 25.

Clinical and molecular correlates of the Index of Severity for Eosinophilic Esophagitis.

Autor: Sato H; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Dellon ES; University of North Carolina, Chapel Hill, NC., Aceves SS; University of California San Diego School of Medicine, San Diego, Rady Children's Hospital, San Diego, Calif., Arva NC; Nationwide Children's Hospital, Columbus, Ohio., Chehade M; Icahn School of Medicine at Mount Sinai, New York, NY., Collins MH; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Davis CM; Baylor College of Medicine, Texas Children's Hospital, Houston, Tex., Falk GW; Penn Medicine, Philadelphia, Pa., Furuta GT; Children's Hospital Colorado, Aurora, Colo., Gonsalves NP; Northwestern University Feinberg School of Medicine, Chicago, Ill., Gupta SK; University of Alabama at Birmingham, Birmingham, Ala., Hirano I; Northwestern University Feinberg School of Medicine, Chicago, Ill., Hiremath G; Vanderbilt University Medical Center, Nashville, Tenn., Katzka DA; Columbia University Irving Medical Center, New York, NY., Khoury P; National Institutes of Health, Bethesda, Md., Leung J; Boston Specialists, Boston, Mass., Menard-Katcher P; University of Colorado Anschutz Medical Campus, Aurora, Colo., Pesek R; University of Arkansas for Medical Science, Little Rock, Ark., Peterson KA; University of Utah Health, Salt Lake City, Utah., Pletneva MA; University of Utah Health, Salt Lake City, Utah., Spergel JM; Children's Hospital of Philadelphia, Philadelphia, Pa., Wechsler JB; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill., Yang GY; Northwestern University Feinberg School of Medicine, Chicago, Ill., Rothenberg ME; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; University of Cincinnati College of Medicine, Cincinnati, Ohio., Shoda T; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: Tetsuo.Shoda@cchmc.org.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 Aug; Vol. 154 (2), pp. 375-386.e4. Date of Electronic Publication: 2024 May 13.

Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy.

Autor: Rawson R; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California., Duong L; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California., Tkachenko E; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California; Department of Medicine, University of California, San Diego, California., Chiang AWT; Department of Pediatrics, University of California, San Diego, California; Department of Bioengineering, University of California, San Diego, California., Okamoto K; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California., Dohil R; Department of Pediatrics, University of California, San Diego, California; Division of Gastroenterology, University of California, San Diego, California; XXX, Rady Children's Hospital, San Diego, California., Lewis NE; Department of Pediatrics, University of California, San Diego, California; Department of Bioengineering, University of California, San Diego, California., Kurten R; Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital Research Institute, Little Rock, Arkansas; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California., Abud EM; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California; XXX, Scripps Research Translational Institute, Scripps Research, San Diego, California., Aceves SS; Department of Pediatrics, University of California, San Diego, California; Division of Allergy Immunology, University of California, San Diego, California; XXX, Rady Children's Hospital, San Diego, California; Department of Medicine, University of California, San Diego, California. Electronic address: saceves@health.ucsd.edu.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2024 Jun; Vol. 17 (3), pp. 315-322. Date of Electronic Publication: 2024 Feb 27.

The Index of Severity for Eosinophilic Esophagitis (I-SEE) Reflects Longitudinal Clinicopathologic Changes in Children.

Autor: Dickerson A; Division of Allergy and Immunology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California; Division of Gastroenterology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California., Kolemen A; Division of Allergy and Immunology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California., Kime K; Division of Allergy and Immunology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California., Chaiboonma K; Division of Allergy and Immunology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California., Dohil R; Division of Gastroenterology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California., Furuta GT; Digestive Health Institute, Children's Hospital Colorado, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, Aurora, Colorado., Dellon ES; Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina., Aceves SS; Division of Allergy and Immunology, Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, California; Department of Medicine, University of California San Diego, San Diego, California. Electronic address: saceves@health.ucsd.edu.

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2024 Apr; Vol. 22 (4), pp. 732-740.e1. Date of Electronic Publication: 2023 Sep 22.