Zobrazeno 1 - 10
of 394
pro vyhledávání: '"Acetylcholine/pharmacology"'
Autor:
Lisa Henkel, Karen Grütz, Anne Grünewald, Anna Kutschenko, Johanne Heine, Selma Staege, Andreas Hermann, Philip Seibler, Hannes Glaß, Norman Kalmbach, Florian Wegner, Thomas Gschwendtberger
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3565, p 3565 (2021)
International journal of molecular sciences 22(7), 3565 (2021). doi:10.3390/ijms22073565
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3565, p 3565 (2021)
International journal of molecular sciences 22(7), 3565 (2021). doi:10.3390/ijms22073565
Myoclonus-dystonia (DYT-SGCE, formerly DYT11) is characterized by alcohol-sensitive, myoclonic-like appearance of fast dystonic movements. It is caused by mutations in the SGCE gene encoding ε-sarcoglycan leading to a dysfunction of this transmembra
Autor:
Alexey Koval, Sven Bergmann, Amiran Keshelava, Vladimir L. Katanaev, Mikhail Kryuchkov, Gonzalo P. Solis, Micha Hersch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Nature Communications, Vol. 9, No 1 (2018) P. 876
Nature Communications
Nature communications, vol. 9, no. 1, pp. 876
Nature Communications, Vol. 9, No 1 (2018) P. 876
Nature Communications
Nature communications, vol. 9, no. 1, pp. 876
G protein-coupled receptors (GPCRs) constitute a large family of receptors that activate intracellular signaling pathways upon detecting specific extracellular ligands. While many aspects of GPCR signaling have been uncovered through decades of studi
Publikováno v:
Aziz, A, Hansen, H S, Sechtem, U, Prescott, E & Ong, P 2017, ' Sex-Related Differences in Vasomotor Function in Patients With Angina and Unobstructed Coronary Arteries ', Journal of the American College of Cardiology, vol. 70, no. 19, pp. 2349-2358 . https://doi.org/10.1016/j.jacc.2017.09.016
BACKGROUND: Coronary vasomotor dysfunction is an important mechanism for angina in patients with unobstructed coronary arteries.OBJECTIVES: The purpose of this study was to determine sex differences in the prevalence and clinical presentation of vaso
Autor:
Craig E. Wheelock, Boye L. Jensen, Maria Peleli, Christa Zollbrecht, Michael Hezel, Eddie Weitzberg, Ming Liu, Alessia Giulietti, Antonio Checa, Mattias Carlström, Jon O. Lundberg
Publikováno v:
Hezel, M, Peleli, M, Liu, M, Zollbrecht, C, Jensen, B L, Checa, A, Giulietti, A, Wheelock, C E, Lundberg, J O, Weitzberg, E & Carlström, M 2016, ' Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation ', Free Radical Biology & Medicine, vol. 99, pp. 87-98 . https://doi.org/10.1016/j.freeradbiomed.2016.07.025
Advanced age is associated with increased risk for cardiovascular disease and type 2 diabetes. A proposed central event is diminished amounts of nitric oxide (NO) due to reduced generation by endothelial NO synthase (eNOS) and increased oxidative str
Autor:
Urs Scherrer, Pierre Dessen, Emrush Rexhaj, David Cerny, Stefano F. Rimoldi, Yves Allemann, Agim Pireva, Ariane Paoloni-Giacobino, Claudio Sartori
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology
American Journal of Physiology. Heart and Circulatory Physiology, Vol. 309, No 7 (2015) pp. H1151-H1156
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
American Journal of Physiology. Heart and Circulatory Physiology, Vol. 309, No 7 (2015) pp. H1151-H1156
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Assisted reproductive technologies (ART) induce vascular dysfunction in humans and mice. In mice, ART-induced vascular dysfunction is related to epigenetic alteration of the endothelial nitric oxide synthase (eNOS) gene, resulting in decreased vascul
Autor:
Jean-Louis Bény, Jacques-Antoine Haefliger, François-Xavier Boittin, Loïc Le Gal, Florian Alonso, Florent Allagnat
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology bi
Cellular physiology and biochemistry, vol. 31, no. 1, pp. 166-178
Cellular Physiology and Biochemistry, Vol 31, Iss 1, Pp 166-178 (2013)
Cellular physiology and biochemistry, vol. 31, no. 1, pp. 166-178
Cellular Physiology and Biochemistry, Vol 31, Iss 1, Pp 166-178 (2013)
BACKGROUND/AIMS Smooth muscle tone is controlled by Ca(2+) signaling in the endothelial layer. Mouse endothelial cells are interconnected by gap junctions made of Connexin40 (Cx40) and Cx37 which allow the exchange of signaling molecules to coordinat
Altered vascular reactivity due to endothelial dysfunction, consequent to vascular damage, is observed in rheumatoid arthritis. We investigated the effect of angiotensin (Ang)-(1-7) on vasculature changes in arthritis induced by complete Freund's adj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::b2fca0c3caed6e1e725e91e4f1f639e5
Autor:
Steeve H. Thany
Publikováno v:
Neurotoxicology
Neurotoxicology, 2009, 30 (6), pp.1045-1052. ⟨10.1016/j.neuro.2009.06.013⟩
Neurotoxicology, 2009, 30 (6), pp.1045-1052. ⟨10.1016/j.neuro.2009.06.013⟩
International audience; Clothianidin is new neonicotinoid insecticide acting selectively on insect nicotinic acetylcholine receptors (nAChRs). Its effects on nAChRs expressed on cercal afferent/giant interneuron synapses and DUM neurons have been stu
Publikováno v:
Journal of vascular research. 44(2):87-98
Understanding vascular pathologies requires insight in the structure and function, and, hence, an imaging technique combining subcellular resolution, large penetration depth, and optical sectioning. We evaluated the applicability of two-photon laser-
Autor:
Christian Fuhrer, Jean-Charles Hoda, R. Ogier, Andreas Wiesner, Mario Raggenbass, Geraldine Allaman, Eric Charpantier, Dominik Feuerbach, Daniel Bertrand, Kyung-Hye Huh
Publikováno v:
Journal of Neuroscience, Vol. 25, No 43 (2005) pp. 9836-9849
Nicotine, a component of tobacco, is highly addictive but possesses beneficial properties such as cognitive improvements and memory maintenance. Involved in these processes is the neuronal nicotinic acetylcholine receptor (nAChR) α7, whose activatio