Impact Study: MK-0646 (Dalotuzumab), Insulin Growth Factor 1 Receptor Antibody Combined with Pemetrexed and Cisplatin in Stage IV Metastatic Non-squamous Lung Cancer

Autor: Peter J. Van Veldhuizen, Stephen K. Williamson, Nora J. Smart, Chao H. Huang, Karen Kelly, Ace Allen, Sarah Spencer, Sarah A. Taylor, Jo Wick, Adelina M. Uypeckcuat, Prakash Neupane, Holly J. Smith

Publikováno v: Frontiers in Oncology
Frontiers in oncology, vol 5, iss JAN
Huang, CH; Williamson, SK; Neupane, P; Taylor, SA; Allen, A; Smart, NJ; et al.(2016). Impact study: MK-0646 (Dalotuzumab), insulin growth factor 1 receptor antibody combined with pemetrexed and cisplatin in stage IV metastatic non-squamous lung cancer. Frontiers in Oncology, 5(JAN), 301. doi: 10.3389/fonc.2015.00301. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6ns5b1j8

© 2016 Huang, Williamson, Neupane, Taylor, Allen, Smart, Uypeckcuat, Spencer, Wick, Smith, Van Veldhuizen and Kelly. Background: Insulin-like growth factor 1 receptor (IGF-1R) regulates cell growth, proliferation, and apoptosis. Adenocarcinoma and n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178d366d06e989311486abcf62f1fd97
https://pubmed.ncbi.nlm.nih.gov/26793618

An analysis of the suitability of home health visits for telemedicine

Autor: Cathy D Boysen, James Patterson, Gary C. Doolittle, Karen Komoroski, Bart Collins, Ace Allen, Milton Wolf

Publikováno v: Journal of Telemedicine and Telecare. 5:90-96

To determine what percentage of traditional home health nursing visits could be done by telemedicine, we carried out a retrospective review of nursing charts clinical records . Data of two types were recorded. The objective data, which were abstracte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5441fc9b09d329e97f1d3b458ea5b0f3
https://doi.org/10.1258/1357633991933387

Practising oncology via telemedicine

Autor: Ace Allen, Gary C. Doolittle

Publikováno v: Journal of Telemedicine and Telecare. 3:63-70

Although there are increasing numbers of telemedicine programmes in the USA, few have offered teleoncology services, so that the role of telemedicine in the practice of clinical oncology has yet to be fully defined. Telemedicine has been used success

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b5de42656d0b2c8e2b4fd4035511f1
https://doi.org/10.1258/1357633971930869

Potential role of platelet-derived growth factor receptor inhibition using imatinib in combination with docetaxel in the treatment of recurrent non-small cell lung cancer

Autor: Chung-Tsen Hsueh, Peter J. Van Veldhuizen, Matthew S. Mayo, Jo Wick, Holly J. Smith, Karen Kelly, Chao H. Huang, Ossama Tawfik, Ace Allen, Adelina M. Uypeckcuat, Stephen K. Williamson

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 6(2)

Introduction: Platelet-derived growth factor receptor (PDGFR) is expressed in lung cancer and is involved in angiogenesis. Preclinical models demonstrated that imatinib (Im) regulates angiogenesis through PDGFR inhibition and enhances efficacy of che

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133c98bac605ea12bcc5417c5c46cf05
https://pubmed.ncbi.nlm.nih.gov/21178640

Cisplatin and novobiocin in the treatment of non-small cell lung cancer. A southwest oncology group study

Autor: John Wendall Goodwin, John Crowley, Laura F. Hutchins, Georgiana K. Ellis, Ace Allen, Robert B. Livingston

Publikováno v: Cancer. 67:2969-2973

Novobiocin, a commercially available oral antibiotic, inhibits DNA topoisomerase II in a manner shown in cell culture to enhance the cytotoxicity of alkylating agents and cisplatin. Thirty-six patients were entered on a Phase II trial using high-dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e62e710fe4460888d94e5a90e0b92c1
https://doi.org/10.1002/1097-0142(19910615)67:12<2969::aid-cncr2820671205>3.0.co