FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF-1α activation

Autor: El Assar, M, Sánchez-Puelles, J M, Royo, I, López-Hernández, E, Sánchez-Ferrer, A, Aceña, J L, Rodríguez-Mañas, L, Angulo, J

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

53 p.-7 fig.
BACKGROUND AND PURPOSE FM19G11 up-regulates mammalian target of rapamycin (mTOR)/hypoxia inducible factor-1α (HIF-1α) and PI3K/Akt pathways, which are involved in endothelial function. We evaluated the effects of FM19G11 on defect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d2a6a1ca18badf481a5469bb1f2775c
http://hdl.handle.net/10261/110358

FM19 G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/ HIF-1α activation.

Autor: El Assar, M, Sánchez ‐ Puelles, J M, Royo, I, López ‐ Hernández, E, Sánchez ‐ Ferrer, A, Aceña, J L, Rodríguez ‐ Mañas, L, Angulo, J

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DBU-catalyzed Michael additions of bulky glycine imine to β-arylfuryl substituted α,β-unsaturated esters.

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