Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.

Autor: Hart KM; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Fabre T; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.; Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, Québec, Canada., Sciurba JC; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Gieseck RL 3rd; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Borthwick LA; Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK., Vannella KM; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Acciani TH; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., de Queiroz Prado R; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Thompson RW; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., White S; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Soucy G; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.; Département de pathologie et biologie cellulaire, Université de Montréal, Montréal, Québec, Canada., Bilodeau M; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.; Département de médecine, Université de Montréal, Montréal, Québec, Canada., Ramalingam TR; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Arron JR; Genentech Inc., South San Francisco, CA 94080, USA., Shoukry NH; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.; Département de médecine, Université de Montréal, Montréal, Québec, Canada., Wynn TA; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. twynn@niaid.nih.gov.

Publikováno v: Science translational medicine [Sci Transl Med] 2017 Jun 28; Vol. 9 (396).

Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ.

Autor: Ramalingam TR; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Gieseck RL; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Acciani TH; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., M Hart K; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Cheever AW; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Mentink-Kane MM; Biomedical Research Institute, Rockville, MD, USA., Vannella KM; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Wynn TA; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.

Publikováno v: The Journal of pathology [J Pathol] 2016 Jul; Vol. 239 (3), pp. 344-54. Date of Electronic Publication: 2016 Jun 10.

Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility.

Autor: Brandt EB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., Biagini Myers JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., Acciani TH; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., Ryan PH; Division of Epidemiology and Biostatistics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., Sivaprasad U; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., Ruff B; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., LeMasters GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio., Bernstein DI; Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio., Lockey JE; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio., LeCras TD; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio., Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Cincinnati, Ohio. Electronic address: Gurjit.Hershey@cchmc.org.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2015 Aug; Vol. 136 (2), pp. 295-303.e7. Date of Electronic Publication: 2015 Mar 04.

Diesel exhaust particle exposure increases severity of allergic asthma in young mice.

Autor: Acciani TH; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Brandt EB, Khurana Hershey GK, Le Cras TD

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2013 Dec; Vol. 43 (12), pp. 1406-18.

Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease.

Autor: Kramer EL; Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA., Hardie WD, Mushaben EM, Acciani TH, Pastura PA, Korfhagen TR, Hershey GK, Whitsett JA, Le Cras TD

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2011 Dec; Vol. 111 (6), pp. 1760-7. Date of Electronic Publication: 2011 Sep 08.