Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Accelerated Publication"'
Autor:
Jens Meiler, Charles R. Sanders, Jeffrey D. Blume, Jeffrey L. Mendenhall, Amanda M. Duran, Brett M. Kroncke
Publikováno v:
Biochemistry
There is a compelling and growing need to accurately predict the impact of amino acid mutations on protein stability for problems in personalized medicine and other applications. Here the ability of 10 computational tools to accurately predict mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140ebce0c054f22658ee24b3284c4f74
https://doi.org/10.1021/acs.biochem.6b00537
https://doi.org/10.1021/acs.biochem.6b00537
Publikováno v:
Behavioural and Cognitive Psychotherapy
Background: Worry about physical health is broadly referred to as health anxiety and can range from mild concern to severe or persistent anxiety such as that found in DSM-IV hypochondriasis. While much is known about anxiety regarding physical health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf9b1fd526804da9e18723c93ceb9e4
http://europepmc.org/articles/PMC4877520
http://europepmc.org/articles/PMC4877520
Publikováno v:
Biochemistry
Proteins from the isc operon of Escherichia coli constitute the machinery used to synthesize iron-sulfur (Fe-S) clusters for delivery to recipient apoproteins. Efficient and rapid [2Fe-2S] cluster transfer from the holo-scaffold protein IscU depends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abe032d66f628fa05c1b2449606e114
https://doi.org/10.1021/bi5010552
https://doi.org/10.1021/bi5010552
Publikováno v:
Biochemistry
Thymidylate, a vital DNA precursor, is synthesized by thymidylate synthases (TSs). A second class of TSs, encoded by the thyX gene, is found in bacteria and a few other microbes and is especially widespread in anaerobes. TS encoded by thyX requires a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0105e1c27762ac58f1b59cdf10a53b01
https://doi.org/10.1021/bi500648n
https://doi.org/10.1021/bi500648n
Publikováno v:
Biochemical Journal
IKKβ {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase β} is required to activate the transcription factor NF-κB, but how IKKβ itself is activated in vivo is still unclear. It was found to require phosphorylation by one or more ‘upstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::731e212e08870fbaa257520d76ff4c7d
http://europepmc.org/articles/PMC4206954
http://europepmc.org/articles/PMC4206954
Publikováno v:
Biochemistry
SEM1(86–107) is a 22-residue peptide corresponding to residues 86–107 in the semenogelin I protein. SEM1(86–107) is an abundant component of freshly liquefied semen and forms amyloid fibrils capable of enhancing HIV infection. To probe the fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eafcc2aec46b470036d75b3f0ba89f1
http://europepmc.org/articles/PMC4039337
http://europepmc.org/articles/PMC4039337
Autor:
Agne, Kazlauskaite, Chandana, Kondapalli, Robert, Gourlay, David G, Campbell, Maria Stella, Ritorto, Kay, Hofmann, Dario R, Alessi, Axel, Knebel, Matthias, Trost, Miratul M K, Muqit
Publikováno v:
Biochemical Journal
We have previously reported that the Parkinson's disease-associated kinase PINK1 (PTEN-induced putative kinase 1) is activated by mitochondrial depolarization and stimulates the Parkin E3 ligase by phosphorylating Ser65 within its Ubl (ubiquitin-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aa0af3494e76422dd3bf8afa4806b227
http://europepmc.org/articles/PMC4000136
http://europepmc.org/articles/PMC4000136
Autor:
Julia Janzen, Elke Mühlberger, Steven C. Ley, Nicholas A. Morrice, Steven Howell, Thorsten Gantke, Sabrina Boussouf
Publikováno v:
Biochemical Journal
Activation of PKR (double-stranded-RNA-dependent protein kinase) by DNA plasmids decreases translation, and limits the amount of recombinant protein produced by transiently transfected HEK (human embryonic kidney)-293 cells. Co-expression with Ebola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c74292a5250f885ef51695960eb11d1
https://doi.org/10.1042/bj20121873
https://doi.org/10.1042/bj20121873
Autor:
Thomas Macartney, Youcef Mehellou, Frances-Rose Schumacher, Axel Knebel, Akihito Ohta, Dario R. Alessi, Nicola T. Wood, Clare Johnson, Thimo Kurz
Publikováno v:
Biochemical Journal
The WNK (with no lysine kinase)–SPAK (SPS1-related proline/alanine-rich kinase)/OSR1 (oxidative stress-responsive kinase 1) signalling pathway plays an important role in controlling mammalian blood pressure by modulating the activity of ion co-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070788786abe18caa6db90ba6b935486
https://doi.org/10.1042/bj20121903
https://doi.org/10.1042/bj20121903
Autor:
Jennifer Wild, Sheena Liness, Georgina Bremner, Richard Stott, Emma Warnock-Parkes, David M. Clark, Anke Ehlers, Nick Grey, Jennifer Readings, Siobhan Commins, Elizabeth Woodward
Publikováno v:
Behavioural and Cognitive Psychotherapy
Background: Randomized controlled trials have established that individual cognitive therapy based on the Clark and Wells (1995) model is an effective treatment for social anxiety disorder that is superior to a range of alternative psychological and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa4ea36c7f6c2c78d75ec39a14a1cf4
http://europepmc.org/articles/PMC3695729
http://europepmc.org/articles/PMC3695729