A deep learning approach to capture the essence of Candida albicans morphologies

Autor: E Kirbizakis, Vanessa Dumeaux, S. Simpson, Raha Parvizi Omran, Malcolm Whiteway, Michael Hallett, C. J. Law, Acbp Costa, V. Bettauer, S Massahi

We present deep learning-based approaches for exploring the complex array of morphologies exhibited by the opportunistic human pathogen C. albicans. Our system entitled Candescence automatically detects C. albicans cells from Differential Image Contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03cb8135c40d07a011567f02db14e22
https://doi.org/10.1101/2021.06.10.445299

A Deep Learning Approach to Capture the Essence of Candida albicans Morphologies.

Autor: Bettauer V; Department of Computer Science and Software Engineering, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Costa ACBP; Department of Biology, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Omran RP; Department of Biology, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Massahi S; Department of Biology, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Kirbizakis E; Department of Biology, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Simpson S; Department of Computer Science and Software Engineering, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Dumeaux V; Department of Anatomy and Cell Biology, Western University, London, Ontario, Canada., Law C; Centre for Microscopy and Cellular Imaging, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Whiteway M; Department of Biology, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada., Hallett MT; Department of Biology, Concordia Universitygrid.410319.e, Montreal, Quebec, Canada.; Department of Biochemistry, Western University, London, Ontario, Canada.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2022 Oct 26; Vol. 10 (5), pp. e0147222. Date of Electronic Publication: 2022 Aug 16.

Candida albicans Mrv8, is involved in epithelial damage and biofilm formation.

Autor: Costa ACBP; Department of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology (ICT); São José dos Campos, Brazil.; Department of Microbial Pathogenicity Mechanisms, Hans-Knoell-Institute, Jena, Germany.; Aberdeen Fungal Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Institute of Medical Sciences, Aberdeen, United Kingdom., Back-Brito GN; Department of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology (ICT); São José dos Campos, Brazil., Mayer FL; Department of Microbial Pathogenicity Mechanisms, Hans-Knoell-Institute, Jena, Germany., Hube B; Department of Microbial Pathogenicity Mechanisms, Hans-Knoell-Institute, Jena, Germany.; Friedrich Schiller University, Jena, Germany., Wilson D; Department of Microbial Pathogenicity Mechanisms, Hans-Knoell-Institute, Jena, Germany.; Aberdeen Fungal Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Institute of Medical Sciences, Aberdeen, United Kingdom.; Medical Research Council Centre for Medical Mycology, School of Biosciences, University of Exeter, Stocker Rd, Exeter EX4 4QD, Exeter, United Kingdom.

Publikováno v: FEMS yeast research [FEMS Yeast Res] 2020 Aug 01; Vol. 20 (5).

Biphasic zinc compartmentalisation in a human fungal pathogen.

Autor: Crawford AC; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom., Lehtovirta-Morley LE; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom.; School of Biological Sciences, University of East Anglia, Norwich, United Kingdom., Alamir O; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom., Niemiec MJ; Department of Clinical Microbiology, Umeå Centre for Microbial Research and Molecular Infection Medicine Sweden, Umeå University, Umeå, Sweden.; Research Group Microbial Immunology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany.; Center for Sepsis Control and Care (CSCC), University Hospital, Jena, Germany., Alawfi B; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom., Alsarraf M; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom., Skrahina V; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany., Costa ACBP; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom., Anderson A; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom., Yellagunda S; Department of Clinical Microbiology, Umeå Centre for Microbial Research and Molecular Infection Medicine Sweden, Umeå University, Umeå, Sweden., Ballou ER; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom.; Institute of Microbiology and Infection, and School of Biosciences, University of Birmingham, Birmingham, United Kingdom., Hube B; Center for Sepsis Control and Care (CSCC), University Hospital, Jena, Germany.; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany.; Friedrich Schiller University, Jena, Germany., Urban CF; Department of Clinical Microbiology, Umeå Centre for Microbial Research and Molecular Infection Medicine Sweden, Umeå University, Umeå, Sweden., Wilson D; Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom.

Publikováno v: PLoS pathogens [PLoS Pathog] 2018 May 04; Vol. 14 (5), pp. e1007013. Date of Electronic Publication: 2018 May 04 (Print Publication: 2018).