Zobrazeno 1 - 10
of 54
pro vyhledávání: '"AcademicSubjects/MED00730"'
Autor:
Deshni Jayathilaka, Chandima Jeewandara, Laksiri Gomes, Tibutius Thanesh Pramanayagam Jayadas, Achala Kamaladasa, Gayasha Somathilake, Dinuka Guruge, Pradeep Darshana Pushpakumara, Thushali Ranasinghe, Inoka Sepali Aberathna, Saubhagya Danasekara, Buddini Gunathilaka, Heshan Kuruppu, Ananda Wijewickrama, Ruwan Wijayamuni, Lisa Schimanski, T K Tan, Graham S Ogg, Alain Townsend, Gathsaurie Neelika Malavige
Publikováno v:
Clinical and Experimental Immunology
To characterize the IgG and IgA responses to different SARS-CoV-2 proteins, we investigated the antibody responses to SARS-CoV-2 following natural infection and following a single dose of AZD1222 (Covishield), in Sri Lankan individuals. The IgG and I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08b3971c7c6b08f92ae4ca2be9749d8
https://doi.org/10.1093/cei/uxac009
https://doi.org/10.1093/cei/uxac009
Autor:
Katie Townsend, Evon Boules, Rachael O’Brien, Sai Murng, Smita Y. Patel, Helen Baxendale, Siraj A. Misbah, Ariharan Anantharachagan, Aarnoud Huissoon, Richard Herriot, Andrew R. Gennery, Kenneth F Baker, David M. Lowe, Lucy Leeman, Suzanne Elcombe, Alex G. Richter, Grant Hayman, Philip D Bright, Moira Thomas, Sarah Goddard, Magdalena Dziadzio, Prashantha M. Vaitla, Sameer Bahal, Betsy Cleave, Dylan James Mac Lochlainn, Elizabeth McDermott, Malini Bhole, Anna Shrimpton, Sujoy Khan, Nisha Verma, William H. Bermingham, Sinisa Savic, Anthony Williams, Gururaj Arumugakani, Lavanya Diwakar, Elizabeth Drewe, James Laffan, Lucy Cliffe, Catherine Stroud, Stephen Jolles, A Herwadkar, Siobhan O. Burns, Adrian M Shields, Shanti Mahabir, Scott Hackett, Sofia Grigoriadou, Sarah Johnston, John Dempster, Hadeil Morsi, Peter Lane, Sadia Noorani, Arthur Price, Tasneem Rahman, Fatima Dhalla, Christopher J A Duncan, Lisa Devlin, Harichandrana Ghanta, Fiona Moghaddas, Charu Chopra, Suranjith Senevirantne, Shuayb Elkhalifa, Rashmi Jain
Publikováno v:
Clinical and Experimental Immunology
Purpose To define the burden of morbidity and mortality arising from COVID-19 in individuals with primary (PID) and secondary immunodeficiency (SID) in the United Kingdom. Methods In March 2020, the United Kingdom Primary Immunodeficiency Network (UK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eed5fd7211e9861f9848e16aa90a01f
https://ora.ox.ac.uk/objects/uuid:6db535d9-055a-4275-bc3f-813e98fa7d36
https://ora.ox.ac.uk/objects/uuid:6db535d9-055a-4275-bc3f-813e98fa7d36
Autor:
Xue-Wei Yang, Hong Li, Ting Feng, Wei Zhang, Xiang-Rong Song, Cheng-Yong Ma, Menzhen Nie, Lijie Wang, Xiaojiao Tan, Yan Kang, Xuelian Liao
Publikováno v:
Clinical and Experimental Immunology
Impairment of antigen-presenting functions is a key mechanism contributing to sepsis-induced immunosuppression. Recently, γδ T cells have been demonstrated as professional antigen-presenting cells (APCs); however, their role in sepsis remains unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d5ecb3b94877f436f31d1a4aeabb54
https://doi.org/10.1093/cei/uxab029
https://doi.org/10.1093/cei/uxab029
Autor:
Patel, Swati, Ramnoruth, Nishta, Wehr, Pascale, Rossjohn, Jamie, Reid, Hugh H, Campbell, Kim, Nel, Hendrik J, Thomas, Ranjeny
Publikováno v:
Clinical and Experimental Immunology
Antigen-specific T cells can serve as a response biomarker in non-clinical or clinical immunotherapy studies in autoimmune disease. There are protocols with optimized multimer staining methods to detect peptide (p)MHCII+ CD4+ T cells, and some qualif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3fe19486b31b2a6e317e148c8f45ce
https://doi.org/10.1093/cei/uxab008
https://doi.org/10.1093/cei/uxab008
Autor:
Panagiotis Karagiannis, Isabel Correa, Jitesh Chauhan, Anthony Cheung, Diana Dominguez-Rodriguez, Manuela Terranova-Barberio, Robert J Harris, Silvia Crescioli, James Spicer, Carsten Bokemeyer, Katie E Lacy, Sophia N Karagiannis
Publikováno v:
Clinical and Experimental Immunology
Human B cells and their expressed antibodies are crucial in conferring immune protection. Identifying pathogen-specific antibodies following infection is possible due to enhanced humoral immunity against well-described molecules on the pathogen surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e45674697b7e5bdc15451b96b1a3ff1
http://europepmc.org/articles/PMC8802180
http://europepmc.org/articles/PMC8802180
Publikováno v:
Clinical and Experimental Immunology
Epidermal melanocyte loss in vitiligo, triggered by stresses ranging from trauma to emotional stress, chemical exposure or metabolite imbalance, to the unknown, can stimulate oxidative stress in pigment cells, which secrete damage-associated molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14314d42b436817ce3fc14d951315534
http://europepmc.org/articles/PMC8802175
http://europepmc.org/articles/PMC8802175
Autor:
Adrian M Shields, Srinivasan Venkatachalam, Salim Shafeek, Shankara Paneesha, Mark Ford, Tom Sheeran, Melanie Kelly, Iman Qureshi, Beena Salhan, Farheen Karim, Neelakshi De Silva, Jacqueline Stones, Sophie Lee, Jahanzeb Khawaja, Praveen Kumar Kaudlay, Richard Whitmill, Ghulam Nabi Kakepoto, Helen M Parry, Paul Moss, Sian E Faustini, Alex G Richter, Mark T Drayson, Supratik Basu
Publikováno v:
Clinical and Experimental Immunology
B-cell-depleting agents are among the most commonly used drugs to treat haemato-oncological and autoimmune diseases. They rapidly induce a state of peripheral B-cell aplasia with the potential to interfere with nascent vaccine responses, particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d41ff1d8834c380bf4fa038baa074dd
https://doi.org/10.1093/cei/uxab018
https://doi.org/10.1093/cei/uxab018
Publikováno v:
Clinical and Experimental Immunology
Alternatively activated macrophages (M2 polarization) play an important role in asthma. Short-chain fatty acids (SCFAs) possessed immune-regulatory functions, but their effects on M2 polarization of alveolar macrophages and its underlying mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9576260dfe49a121c98e162bfb94977e
https://doi.org/10.1093/cei/uxab028
https://doi.org/10.1093/cei/uxab028
Publikováno v:
Clinical and Experimental Immunology
Summary NLRP3 inflammasome hyperactivation contributes to neuroinflammation in autoimmune disorders, but the underlying regulatory mechanism remains to be elucidated. We demonstrate that compared with wild-type (WT) mice, mice lacking thymic stromal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27966717231acb4a3161cd39cfbc7b54
https://doi.org/10.1093/cei/uxab023
https://doi.org/10.1093/cei/uxab023
Autor:
Chruscinski, Andrzej, Rojas-Luengas, Vanessa, Moshkelgosha, Sajad, Issachar, Assaf, Luo, Jane, Yowanto, Handy, Lilly, Leslie, Smith, Robert, Renner, Eberhard, Zhang, Jianhua, Epstein, Maor, Grant, David, McEvoy, Caitriona M, Konvalinka, Ana, Humar, Atul, Adeyi, Oyedele, Fischer, Sandra, Volmer, Felix H, Taubert, Richard, Jaeckel, Elmar, Juvet, Stephen, Selzner, Nazia, Levy, Gary A
Publikováno v:
Clinical and Experimental Immunology
LITMUS was a single-centre, Phase 2a study designed to investigate whether the gene biomarker FGL2/IFNG previously reported for the identification of tolerance in murine models could identify operationally tolerant liver transplant recipients. Multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a66a4ade92def42ed7825a9f30edb3
https://doi.org/10.1093/cei/uxab011
https://doi.org/10.1093/cei/uxab011