Prognostic impact of tumor-specific insulin-like growth factor binding protein 7 (IGFBP7) levels in breast cancer: a prospective cohort study

Autor: Somayeh Khazaei, Ana Bosch, Helena Jernström, Christopher Godina, Edward Visse, Karolin Isaksson, Helga Tryggvadottir, Karin Jirström, Björn Nodin, Signe Borgquist

Publikováno v: Godina, C, Khazaei, S, Tryggvadottir, H, Visse, E, Nodin, B, Jirström, K, Borgquist, S, Bosch, A, Isaksson, K & Jernström, H 2021, ' Prognostic impact of tumor-specific insulin-like growth factor binding protein 7 (IGFBP7) levels in breast cancer : A prospective cohort study ', Carcinogenesis, vol. 42, no. 11, pp. 1314-1325 . https://doi.org/10.1093/carcin/bgab090
Carcinogenesis

The prognostic impact of insulin-like growth factor binding protein 7 (IGFBP7) in breast cancer is unclear. Host factors, including lifestyle, anthropometry and metabolic profile, might influence tumor-specific IGFBP7. This study aimed to investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccc7b49b753aaace2171e6a33b905d5
https://doi.org/10.1093/carcin/bgab090

Dietary interventions to prevent high-fructose diet–associated worsening of colitis and colitis-associated tumorigenesis in mice

Autor: Hannah A Staab, Andrew J. Dannenberg, Ryohei Nishiguchi, Hanhan Wang, Taehoon Ha, Rhonda K. Yantiss, Srijani Basu, David C. Montrose, Xi Kathy Zhou, Melanie Johncilla, Naotake Ito

Publikováno v: Carcinogenesis

Diet is believed to be an important factor in the pathogenesis of inflammatory bowel disease. High consumption of dietary fructose has been shown to exacerbate experimental colitis, an effect mediated through the gut microbiota. This study evaluated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63d8f3ea4a4d5fb035844b7a7c6349a
http://europepmc.org/articles/PMC8215596

DPYD, down-regulated by the potentially chemopreventive agent luteolin, interacts with STAT3 in pancreatic cancer

Autor: Aya Naiki-Ito, Satoru Takahashi, Masayuki Komura, Kenta Kachi, Shugo Suzuki, Taku Naiki, Kenju Nakao, Yoichi Matsuo, Akihisa Kato, Hiroyuki Kato, Shingo Inaguma

Publikováno v: Carcinogenesis

The 5-year survival rate of pancreatic ductal carcinoma (PDAC) patients is
This study describes the chemopreventive effects of luteolin on pancreatic carcinogenesis via STAT3 inactivation caused by DPYD down-regulation, resulting in suppression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68071e2b28a277492a1e4da04374ad3b
http://europepmc.org/articles/PMC8283735

Hsa_circRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway

Autor: Baochun Wang, Weiwei Huang, Manni Cai, Mengqiong Wu, Cancan Kong, Xin Liu, Yiming Chen

Publikováno v: Carcinogenesis

CircRNAs (circular RNAs), recently identified as a critical regulator in tumorigenesis, participate in CRC (colorectal cancer) growth. However, the role of hsa_circRNA_002144 in CRC was poorly understood. Firstly, hsa_circRNA_002144 showed significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907fe4181555a609d982eafe5f4bb55e
https://doi.org/10.1093/carcin/bgaa140

Cooperative participation of epigenomic and genomic alterations in the clinicopathological diversity of gastric adenocarcinomas: significance of cell adhesion and epithelial–mesenchymal transition-related signaling pathways

Autor: Hitoshi Katai, Teruhiko Yoshida, Hiromi Sakamoto, Hirohiko Totsuka, Hirokazu Taniguchi, Suenori Chiku, Yoriko Takahashi, Yae Kanai, Menghan Yang, Eri Arai

Publikováno v: Carcinogenesis

The present study was conducted to clarify the cooperative significance of epigenomic and genomic abnormalities during gastric carcinogenesis. Using 21 samples of normal control gastric mucosa (C), 109 samples of non-cancerous gastric mucosa (N) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3e68afd47eecb50e5c260278fb2adc
http://europepmc.org/articles/PMC7665242