Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Acacia White"'
Autor:
Rohan Umesh Parekh, Acacia White, Korin E. Leffler, Vinicia C. Biancardi, Jeffrey B. Eells, Abdel A. Abdel-Rahman, Srinivas Sriramula
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Brain orexin system hyperactivity contributes to neurogenic hypertension. We previously reported upregulated neuronal kinin B1 receptor (B1R) expression in hypertension. However, the role of central B1R activation on the orexin system in neu
Externí odkaz:
https://doaj.org/article/0f24aa450bba48339c5666834dc98b1b
Autor:
Acacia White, Rohan Umesh Parekh, Drew Theobald, Pranaya Pakala, Ariel Lynn Myers, Rukiyah Van Dross, Srinivas Sriramula
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The endoplasmic reticulum (ER) is a key organelle involved in homeostatic functions including protein synthesis and transport, and the storage of free calcium. ER stress potentiates neuroinflammation and neurodegeneration and is a key contributor to
Externí odkaz:
https://doaj.org/article/280b4e7eefb54d81a00647807fcc53dd
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Despite many readily available therapies, hypertensive kidney disease remains the second most prevalent cause of end-stage renal disease after diabetes, and continues to burden patient populations and escalate morbidity and mortality rates. Kinin B1
Externí odkaz:
https://doaj.org/article/e33df1ea47c94d0bb8569be633234c7a
Autor:
Acacia White, Srinivas Sriramula
Publikováno v:
Physiology. 38
Objectives: Kininase I, or carboxypeptidase M and N (CPM/CPN), metabolizes bradykinin and kallidin into endogenous kinin B1 receptor (B1R) agonists. B1R expression in the brain is linked to neuroinflammation and autonomic dysfunction, and the develop
Autor:
Jeffrey B. Eells, Korin E. Leffler, Srinivas Sriramula, Rohan Umesh Parekh, Acacia White, Abdel A. Abdel-Rahman, Vinicia C. Biancardi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Brain orexin system hyperactivity contributes to neurogenic hypertension. We previously reported upregulated neuronal kinin B1 receptor (B1R) expression in hypertension. However, the role of central B1R activation on the orexin system in neurogenic h
Publikováno v:
The FASEB Journal. 36