Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Acacia, Lamb"'
Publikováno v:
Pediatrics. 144:579-579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc9e038010f88c33a193d73fe06bb7b
https://doi.org/10.1542/peds.144.2ma6.579
https://doi.org/10.1542/peds.144.2ma6.579
Publikováno v:
Cellular Signalling. 22:1282-1290
The eukaryotic transcription factor NF-kappaB regulates a wide range of host genes that control the inflammatory and immune responses, programmed cell death, cell proliferation and differentiation. The activation of NF-kappaB is tightly controlled bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6829609349953885ac2f56044a84e907
https://doi.org/10.1016/j.cellsig.2010.03.017
https://doi.org/10.1016/j.cellsig.2010.03.017
Autor:
Acacia Lamb, Lin Feng Chen
Publikováno v:
Gut Microbes. 1:109-113
Many of the pathologies linked to Helicobacter pylori are caused by the ability of the bacteria to induce chronic inflammation in the stomach of the host. One of the major transcription factors that regulate inflammation is NFκB, which is constituti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c069a7e751c3cce273510484131541a
https://doi.org/10.4161/gmic.1.2.11587
https://doi.org/10.4161/gmic.1.2.11587
Autor:
Acacia Lamb, Lin Feng Chen
Many factors are known to contribute to the development of cancer, and gastric cancer development is no different. Chronic infections, tobacco smoke, diet, and obesity are all major factors which play into the development of cancer [Aggarwal and Gehl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bce8d8ab48437749ca132f8c722c6c
https://europepmc.org/articles/PMC3909030/
https://europepmc.org/articles/PMC3909030/
Publikováno v:
Journal of cellular biochemistry. 114(10)
The Helicobacter pylori virulence factor CagA targets a variety of host proteins to alter different cellular responses, including the induction of pro-inflammatory cytokines. We have previously shown that CagA-facilitated lysine 63-linked ubiquitinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f37996b2e553f85e3a994c67c4df6f2
https://pubmed.ncbi.nlm.nih.gov/23606331
https://pubmed.ncbi.nlm.nih.gov/23606331
Autor:
Acacia Lamb, Kunihiko Ito, Richard M. Peek, Bo Huang, Yoshiaki Ito, Judith Romero-Gallo, Lin Feng Chen, Y. H.N. Tsang
Chronic infection with cagA-positive Helicobacter pylori is the strongest risk factor for the development of gastric adenocarcinoma. The cagA gene product CagA is injected into gastric epithelial cells and disturbs cellular functions by physically in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc581fa56c294deb718286921e4eb98
https://europepmc.org/articles/PMC2980823/
https://europepmc.org/articles/PMC2980823/
Publikováno v:
Epigenetics. 4(7)
Recent studies on the lysine methylation of histones have moved rapidly thanks to the discoveries of a variety of histone lysine methyltransferases. Histone lysine methylation is known to either activate or repress gene expression depending upon the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df73b7ba8d7fd0fa27cde0b4bd486276
https://pubmed.ncbi.nlm.nih.gov/19829087
https://pubmed.ncbi.nlm.nih.gov/19829087
Proper regulation of NF-kappaB activity is critical to maintain and balance the inflammatory response. Inactivation of the NF-kappaB complex relies in part on the proteasome-mediated degradation of promoter-bound NF-kappaB, but the detailed molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a426f1dfe413508b25305d87c14132c2
https://europepmc.org/articles/PMC2683704/
https://europepmc.org/articles/PMC2683704/
Recent studies have emphasized the importance of cellular microenvironment in modulating cell growth and signaling. In vitro, collagen matrices, Matrigel, and other synthetic support systems have been used to simulate in vivo microenvironments, and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a27b157a4b644f16d364400298490d
https://europepmc.org/articles/PMC2603546/
https://europepmc.org/articles/PMC2603546/
Autor:
Acacia Lamb, Lin Feng Chen, Jiang Dong Li, Steven R. Blanke, Richard M. Peek, Masanori Hatakeyama
Publikováno v:
EMBO reports. 11:11-12
We appreciate the comments from Schweitzer et al in this issue about our discovery that Helicobacter pylori cytotoxin‐associated gene A (CagA) activates nuclear factor κB (NF‐κB), as they reveal the lack of consensus on the role that CagA plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdd06bb883d6b43436b9a2f0e5991f3
https://doi.org/10.1038/embor.2009.269
https://doi.org/10.1038/embor.2009.269