The Effect of Inflammatory Bowel Disease and Irritable Bowel Syndrome on Pravastatin Oral Bioavailability: In vivo and in silico evaluation using bottom-up wbPBPK modeling.

Autor: Alsmadi MM; Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan. mmalsmadi@just.edu.jo.; Nanotechnology Institute, Jordan University of Science and Technology, Irbid, Jordan. mmalsmadi@just.edu.jo., Abudaqqa AA; Faculty of Pharmacy and Biomedical Sciences, University of Petra, Amman, Jordan., Idkaidek N; Faculty of Pharmacy and Biomedical Sciences, University of Petra, Amman, Jordan., Qinna NA; Faculty of Pharmacy and Biomedical Sciences, University of Petra, Amman, Jordan.; University of Petra Pharmaceutical Center (UPPC), University of Petra, Amman, Jordan., Al-Ghazawi A; Triumpharma LLC, Amman, Jordan.

Publikováno v: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Apr 11; Vol. 25 (4), pp. 86. Date of Electronic Publication: 2024 Apr 11.