Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Abscission checkpoint"'
Autor:
Dawn M Wenzel, Douglas R Mackay, Jack J Skalicky, Elliott L Paine, Matthew S Miller, Katharine S Ullman, Wesley I Sundquist
Publikováno v:
eLife, Vol 11 (2022)
The 12 related human ESCRT-III proteins form filaments that constrict membranes and mediate fission, including during cytokinetic abscission. The C-terminal tails of polymerized ESCRT-III subunits also bind proteins that contain Microtubule-Interacti
Externí odkaz:
https://doaj.org/article/cc5c47a4664040128fa579ea2adf3aa6
Autor:
Sadler, Jessica B. A., Wenzel, Dawn M., Williams, Lauren K., Guindo-Martínez, Marta, Alam, Steven L., Mercader, Josep M., Torrents, David, Ullman, Katharine S., Sundquist, Wesley I., Martin-Serrano, Juan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Sep . 115(38), E8900-E8908.
Externí odkaz:
https://www.jstor.org/stable/26531175
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Accurate chromosome segregation requires the removal of all chromatin bridges, which link chromosomes before cell division. When chromatin bridges fail to be removed, cell cycle progression may halt, or cytokinesis failure and ensuing polyploidizatio
Externí odkaz:
https://doaj.org/article/5308c14ff6254ad59216ad3500369833
Autor:
Eleni Petsalaki, George Zachos
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 2 (2021)
In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage. Here, we discuss recent findings from our lab showing that an ATM-CHK2-INCENP pathway imposes the
Externí odkaz:
https://doaj.org/article/e23aefe0978a47aa911ea367a23eb126
Autor:
Eleni Petsalaki, George Zachos
Publikováno v:
Cells, Vol 10, Iss 12, p 3350 (2021)
The abscission checkpoint contributes to the fidelity of chromosome segregation by delaying completion of cytokinesis (abscission) when there is chromatin lagging in the intercellular bridge between dividing cells. Although additional triggers of an
Externí odkaz:
https://doaj.org/article/850eef0f6f6d45428177d24ca9037a13
Akademický článek
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Akademický článek
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Autor:
Khalil Davis, David J. Mann, Ulrike S. Eggert, John D. Scott, Steven Lynham, Victoria Crossland, Xiaoping Yang, Tanya N. Soliman, Peter J. Parker, Alan Armstrong, Neil Q. McDonald, Lisa Watson, Joanna R. Kelly, Nicola Lockwood
Publikováno v:
Biochemical Journal
A requirement for PKCε in exiting from the Aurora B dependent abscission checkpoint is associated with events at the midbody, however, the recruitment, retention and action of PKCε in this compartment are poorly understood. Here, the prerequisite f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d85219ff82fd92ec0f42d125307988a
http://europepmc.org/articles/PMC8238520
http://europepmc.org/articles/PMC8238520
Akademický článek
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Autor:
Arnaud Echard, Hugo Wioland, Frédérique Cuvelier, Guillaume Romet-Lemonne, Tamara Advedissian, Jian Bai
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (8), pp.4169-4179. ⟨10.1073/pnas.1911629117⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (8), pp.4169-4179. ⟨10.1073/pnas.1911629117⟩
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (8), pp.4169-4179. ⟨10.1073/pnas.1911629117⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (8), pp.4169-4179. ⟨10.1073/pnas.1911629117⟩
Proc Natl Acad Sci U S A
International audience; Abscission is the terminal step of cytokinesis leading to the physical separation of the daughter cells. In response to the abnormal presence of lagging chromatin between dividing cells, an evolutionarily conserved abscission/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5139df330b93d415d9a12ca7d187948c
https://doi.org/10.1073/pnas.1911629117
https://doi.org/10.1073/pnas.1911629117