Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Absalon D. Gutierrez"'
Autor:
Daeeun Kim, Aylin Memili, Hung-Hsin Chen, Heather M. Highland, Hannah G. Polikowsky, Mohammad Yaser Anwar, Susan T. Laing, Miryoung Lee, Joseph B. McCormick, Susan P. Fisher-Hoch, Jennifer E. Below, Kari E. North, Absalon D. Gutierrez
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background Adipokines are hormones secreted from adipose tissue and are associated with cardiometabolic diseases (CMD). Functional differences between adipokines (leptin, adiponectin, and resistin) are known, but inconsistently reported asso
Externí odkaz:
https://doaj.org/article/74308203e36f4a2fb9399e858e87613a
Publikováno v:
Diabetes. 71
Mechanisms underlying antidiabetes effects of GLP-1 analogs such as liraglutide, collectively termed incretins, remain incompletely understood. While incretins boost insulin secretion, they also modulate the immune system and have anti-obesity effect
Autor:
Sara Coverdale, Liang Zhu, Vala Hamidi, Absalon D. Gutierrez, Charles C. Miller, Kayla A. Riggs, Karla Bermudez Saint Andre, Christian M. Westby, Hongyu Wang, A. Dursteler, Heinrich Taegtmeyer
Publikováno v:
Metab Syndr Relat Disord
Background: The state of prediabetes comprises atherosclerotic changes leading to decreased vascular function in humans. This study examined the effects on incretin mimetics on vascular physiology in the prediabetic postprandial state. Methods: Fifte
Autor:
Absalon D. Gutierrez, Zhanguo Gao, Vala Hamidi, Liang Zhu, Karla Bermudez Saint Andre, Kayla Riggs, Monika Ruscheinsky, Hongyu Wang, Yongmei Yu, Charles Miller, Hernan Vasquez, Heinrich Taegtmeyer, Mikhail G. Kolonin
Publikováno v:
Cell reports. Medicine. 3(11)
Mechanisms underlying anti-diabetic effects of GLP1 analogs remain incompletely understood. We observed that in prediabetic humans exenatide treatment acutely induces interleukin-6 (IL-6) secretion by monocytes and IL-6 in systemic circulation. We hy
Autor:
Ashok Balasubramanyam, Mustafa Tosur, Ruchi Gaba, Kurt M. Bohren, Absalon D. Gutierrez, Farook Jahoor, Eunice I. Caducoy, Nalini Ram, Adriana J. Cardenas, Jean W. Hsu
Publikováno v:
Diabetes. 69
We previously showed that patients with A-β+ KPD (“obese ketosis-prone type 2 diabetes”) have diminished intracellular arginine availability that may impair their ability to generate an adequate beta cell response in the face of hyperglycemia, a
Autor:
Neel L Shah, Elena Thampy Cherian, Marc Cillo, Sapna Naik, Philip R. Orlander, Absalon D. Gutierrez, Katie Guttenberg
Publikováno v:
Journal of the Endocrine Society
Background: Intravenous etomidate infusion, in non-hypnotic doses, rapidly lowers cortisol levels by blocking 11-beta hydroxylation of deoxycortisol to inhibit cortisol production. It is an underutilized drug due to concerns of excess sedation and IC
Autor:
Carlos A. Flores, Miryoung Lee, MinJae Lee, Joseph B. McCormick, Masha Resman, Sapna Naik, Parisa Asgarisabet, Susan P. Fisher-Hoch, Absalon D. Gutierrez
Publikováno v:
Cytokine. 148:155687
Links between resistin, insulin resistance (IR), and resistin-stimulated cytokine signaling remain unknown in Mexican-Americans. A Mexican-American cohort was examined to determine (1) relationships between circulating resistin and IR, (2) resistin's
Autor:
Keziah M Thomas, Reem Al-Dallal, Absalon D. Gutierrez, Susan P. Fisher-Hoch, MinJae Lee, Joseph B. McCormick, Aysha Chaudhri
Publikováno v:
Journal of the Endocrine Society
Adipocytokines are hormones released from adipose cells. Their functions range from regulating hunger to regulating the metabolic effects of insulin. What role these hormones play in metabolic health and diabetes have not been studied in the Hispanic
Autor:
MinJae Lee, Masha Resman, Parisa Asgarisabet, Carlos A. Flores, Susan P. Fisher-Hoch, Susan T. Laing, Absalon D. Gutierrez, Miryoung Lee, Joseph B. McCormick, Sapna Naik
Publikováno v:
Diabetes. 67
Background: Epidemiological studies suggest that increased levels of leptin and resistin, and decreased levels of adiponectin are associated with worsening insulin resistance (IR) and atherosclerosis. However, it is unclear if these findings apply to
Autor:
Vala Hamidi, Nitya K. Kumar, Monika Ruscheinsky, Kayla A. Riggs, Karla Bermudez, Sara Coverdale, Absalon D. Gutierrez, A. Dursteler
Publikováno v:
Diabetes. 67
Incretin mimetic medications acutely downregulate inflammation via the NfkB pathway during the fasting state in humans with type 2 diabetes mellitus. Free fatty acids (FFAs) activate TLR4, stimulating NFkB and the production of IL-6, which downregula