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Na+, K+-ATPase activity in children with autism spectrum disorder: Searching for the reason(s) of its decrease in blood cells

Autor: Bolotta A, Visconti P, Fedrizzi G, Ghezzo A, Marini M, Manunta P, Messaggio E, Posar A, Vignini A, Abruzzo PM

Na+, K+-ATPase (NKA) activity, which establishes the sodium and potassium gradient across the cell membrane and is instrumental in the propagation of the nerve impulses, is altered in a number of neurological and neuropsychiatric disorders, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a5e2a7247ac374b7482211f4e10bb3b

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Plasma peroxiredoxin changes and inflammatory cytokines support the involvement of neuro-inflammation and oxidative stress in Autism Spectrum Disorder

Autor: Alessandro Matte, Tiziana Guarnieri, Enrica Federti, Alessandra Bolotta, Paola Visconti, Angela Siciliano, Provvidenza Maria Abruzzo, Annio Posar, Marina Marini, L De Franceschi, Alessandro Ghezzo

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Journal of Translational Medicine

Background It has been established that children with Autism Spectrum Disorders (ASD) are affected by oxidative stress, the origin of which is still under investigation. In the present work, we evaluated inflammatory and pro-oxidant soluble signature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3ab73143b1907b55e1ecc0735fa22b
http://link.springer.com/article/10.1186/s12967-019-2076-z

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Oxidative Stress in Autistic Children Alters Erythrocyte Shape in the Absence of Quantitative Protein Alterations and of Loss of Membrane Phospholipid Asymmetry

Autor: Paola Visconti, Michela Battistelli, Alessandra Bolotta, Marina Marini, Stefano Manfredini, Annio Posar, Maria Cristina Manara, Provvidenza Maria Abruzzo, Elisabetta Falcieri, Alessandro Ghezzo

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)

Red blood cells (RBCs) from people affected by autism spectrum disorders (ASDs) are a target of oxidative stress. By scanning electron microscopy, we analyzed RBC morphology from 22 ASD children and show here that only 47.5 ± 3.33% of RBC displayed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b125471a8f06b2da3e2c38ef7b4d28

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Moderate Exercise Training Induces ROS-Related Adaptations to Skeletal Muscles

Autor: Arsenio Veicsteinas, Stefania Fulle, Silvia Belia, S. di Tullio, Provvidenza Maria Abruzzo, Fabio Esposito, Cosetta Marchionni, Marina Marini

Publikováno v: International Journal of Sports Medicine. 34:676-687

Aim of the present work was the evaluation of the effects of moderate exercise training on two skeletal muscles differing for fibre-type composition, Tibialis Anterior (TA) and Soleus (SOL). Fibre adaptations, including their metabolic shift and mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dd704d28d031707a3e5394333753e7
https://doi.org/10.1055/s-0032-1323782

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Proteomic analysis and protein carbonylation profile in trained and untrained rat muscles

Autor: Claudia Fiorillo, Arsenio Veicsteinas, Tania Gamberi, Francesca Magherini, Luca Bini, Marina Marini, Provvidenza Maria Abruzzo, Michele Puglia, Massimo Gulisano, Fabio Esposito, Alessandra Modesti

Publikováno v: Journal of Proteomics. 75:978-992

Understanding the relationship between physical exercise, reactive oxygen species and skeletal muscle modification is important in order to better identify the benefits or the damages that appropriate or inappropriate exercise can induce. Unbalanced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989db78e99949b73cb97d24b15bcd53c
https://doi.org/10.1016/j.jprot.2011.10.017

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Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features

Autor: Francesca Raffaelli, Stefano Manfredini, Federica Resca, Gemma Malisardi, Emanuela Pipitone, Provvidenza Maria Abruzzo, Alessandro Ghezzo, Laura Nanetti, Paola Visconti, Laura Mazzanti, Giuseppe Gobbi, Carla Ferreri, Marina Marini, Arianna Vignini, Alessandra Bolotta

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e66418 (2013)
PloS one 8 (2013). doi:10.1371/journal.pone.0066418
info:cnr-pdr/source/autori:Ghezzo, Alessandro; Visconti, Paola; Abruzzo, Provvidenza M.; Bolotta, Alessandra; Ferreri, Carla; Gobbi, Giuseppe; Malisardi, Gemma; Manfredini, Stefano; Marini, Marina; Nanetti, Laura; Pipitone, Emanuela; Raffaelli, Francesca; Resca, Federica; Vignini, Arianna; Mazzanti, Laura/titolo:Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features/doi:10.1371%2Fjournal.pone.0066418/rivista:PloS one/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume:8

It has been suggested that oxidative stress may play a role in the pathogenesis of Autism Spectrum Disorders (ASD), but the literature reports somewhat contradictory results. To further investigate the issue, we evaluated a high number of peripheral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f3b805f39e2e37fd1611e67b4e93a7
http://hdl.handle.net/11392/1869729

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IN VIVO SUPPLEMENTATION OF CREATINE AND RIBOSE PRESERVES HYPOXIC HEARTS FROM APOPTOSIS AND RIGHT VENTRICLE HYPERTROPHY

Autor: ABRUZZO, PROVVIDENZA MARIA, BOLOTTA, ALESSANDRA, MARINI, MARINA, Caretti A, Bianciardi P, Samaja M, Terruzzi C, Lucchina F

It was previously found that H9c2 cardiomyocytes exposed to 24-h ischemia (1% O2 with glucose deprivation), were rescued by administration of 2.5 mM creatine + 5 mM D-ribose, while creatine or D-ribose alone were ineffective (1). These findings corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::72c1249a6abb3bb6a283db0ac278a928
http://hdl.handle.net/11585/144507

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Proteomic analysis and protein carbonylation profile in trained and untrained rat muscles

Autor: Magherini F, Puglia M, Bini L, Gamberi T, Modesti A., ABRUZZO, PROVVIDENZA MARIA, MARINI, MARINA

Understanding the relationship between physical exercise, reactive oxygen species (ROS) and skeletal muscle modification is important in order to better identify the benefits or the damages that appropriate or inappropriate exercise can induce. Unbal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::d65955127728d5c3871d4b869c929a96
http://hdl.handle.net/11585/144502

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Oxidative stress in Friedriech's Ataxia patients: effect of tocotrienol supplementation

Autor: ABRUZZO, PROVVIDENZA MARIA, BOLOTTA, ALESSANDRA, MARCHIONNI, COSETTA, MARINI, MARINA, Modesti A, Gamberi T, Malisardi G, Ferreri C

Friedreich’s Ataxia (FRDA) is characterized by oxidative stress as well as by impaired mitochondrial functions. Patients are currently treated with idebenone, a CoQ10 analogue, and the therapeutic efficacy of Vit. E has been documented. In order to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::082212d004b02b980ee6edb6a4e416bd
http://hdl.handle.net/11585/144499

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