Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial

Autor: Simonis, F.D., Neto, A.S., Binnekade, J.M., Braber, A., Bruin, K.C.M., Determann, R.M., Goekoop, G.J., Heidt, J., Horn, J., Innemee, G., Jonge, E. de, Juffermans, N.P., Spronk, P.E., Steuten, L.M., Tuinman, P.R., Wilde, R.B.P. de, Vriends, M., Abreu, M.G. de, Pelosi, P., Schultz, M.J., Writing Grp PReVENT Investigators

Publikováno v: JAMA, 320(18), 1872-1880. American Medical Association
JAMA-Journal of the American Medical Association, 320(18), 1872-1880. American Medical Association
Simonis, F D, Serpa Neto, A, Binnekade, J M, Braber, A, Bruin, K C M, Determann, R M, Goekoop, G-J, Heidt, J, Horn, J, Innemee, G, de Jonge, E, Juffermans, N P, Spronk, P E, Steuten, L M, Tuinman, P R, de Wilde, R B P, Vriends, M, Gama de Abreu, M, Pelosi, P & Schultz, M J 2018, ' Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial ', JAMA-Journal of the American Medical Association, vol. 320, no. 18, pp. 1872-1880 . https://doi.org/10.1001/jama.2018.14280
Journal of the American Medical Association, 320(18), 1872-1880

Importance It remains uncertain whether invasive ventilation should use low tidal volumes in critically ill patients without acute respiratory distress syndrome (ARDS). Objective To determine whether a low tidal volume ventilation strategy is more ef

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