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pro vyhledávání: '"Abramo J. Manfredonia"'
Autor:
Abramo J. Manfredonia, Daniel A. Kraut
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 750 (2022)
The ubiquitin–proteasome system is responsible for the bulk of protein degradation in eukaryotic cells. Proteins are generally targeted to the 26S proteasome through the attachment of polyubiquitin chains. Several proteins also contain ubiquitin-in
Externí odkaz:
https://doaj.org/article/6bc6abe7df4441718a81e6df00113c33
Autor:
Christopher Eric Braganca, Julianna Rose Cresti, Joseph A. Boscia, Abramo J. Manfredonia, Christina M. Hurley, Mary D. Cundiff, Daniel A. Kraut
Publikováno v:
Proc Natl Acad Sci U S A
The 26S proteasome is the macromolecular machine responsible for the bulk of protein degradation in eukaryotic cells. As it degrades a ubiquitinated protein, the proteasome transitions from a substrate-accepting conformation (s1) to a set of substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831b3bc1ae214dd3472d515e9219a0a1
https://doi.org/10.1073/pnas.2101004118
https://doi.org/10.1073/pnas.2101004118