Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Abrahim I Orabi"'
Autor:
Abrahim I Orabi, Yuhuan Luo, Mahwish U Ahmad, Ahsan U Shah, Zahir Mannan, Dong Wang, Sheharyar Sarwar, Kamaldeen A Muili, Christine Shugrue, Thomas R Kolodecik, Vijay P Singh, Mark E Lowe, Edwin Thrower, Ju Chen, Sohail Z Husain
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48465 (2012)
Acute pancreatitis is a painful, life-threatening disorder of the pancreas whose etiology is often multi-factorial. It is of great importance to understand the interplay between factors that predispose patients to develop the disease. One such factor
Externí odkaz:
https://doaj.org/article/889a475c5cc141099dabea9b3f1a094c
Autor:
Kristy Boggs, Ting Wang, Abrahim I. Orabi, Amitava Mukherjee, John F. Eisses, Tao Sun, Li Wen, Tanveer A. Javed, Farzad Esni, Wei Chen, Sohail Z. Husain
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract It is well known that pancreatic recovery after a single episode of injury such as an isolated bout of pancreatitis occurs rapidly. It is unclear, however, what changes are inflicted in such conditions to the molecular landscape of the pancr
Externí odkaz:
https://doaj.org/article/69e80f3f1fcb461aaae46aed4750a6cc
Autor:
Fateema T. Rose, Sohail Z. Husain, Craig A. Byersdorfer, Abrahim I. Orabi, Mark E. Lowe, Kim Ritchey, Rose Turner, Judy-April Oparaji, Amari Howard, Qi Mi, Debra Okafor
Publikováno v:
Journal of Clinical Gastroenterology. 51:907-913
Goals To evaluate potential risk factors for the development of asparaginase-associated pancreatitis (AAP), we performed a systematic review of the current literature from January 1946 through May 2015. Background Asparaginase, a primary treatment fo
Autor:
Mark S. Cattral, Li Xie, Erin Winter, Laura I. Cosen-Binker, Tao Liang, Subhankar Dolai, Herbert Y. Gaisano, Ya Chi Huang, Peter Thorn, Negar Karimian, Abrahim I. Orabi
Publikováno v:
Journal of Biological Chemistry. 292:5957-5969
A genuine understanding of human exocrine pancreas biology and pathobiology has been hampered by a lack of suitable preparations and reliance on rodent models employing dispersed acini preparations. We have developed an organotypic slice preparation
Autor:
Farzad Esni, Tanveer A. Javed, Subramaniam Sanker, Tianming Le, Krishna Prasadan, Ping Guo, George K. Gittes, Abrahim I. Orabi, Carlos A. Castro, Li Wen, Sohail Z. Husain, Xiangwei Xiao, David Ricks, Kristy Boggs, John F. Eisses
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 1, Pp 119-128 (2017)
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 1, Pp 119-128 (2017)
Background & Aims: There is a pressing need to develop effective preventative therapies for postâendoscopic retrograde cholangiopancreatography pancreatitis (PEP). We showed that early PEP events are induced through the calcium-activated phosphatase
Autor:
Debbie C. Thurmond, Nestor A. Fernandez, Douglas Holmyard, Peter Thorn, Subhankar Dolai, Tanveer A. Javed, Mark S. Cattral, Tao Liang, Li Xie, Abrahim I. Orabi, Herbert Y. Gaisano, Huanli Xie
Publikováno v:
The Journal of biological chemistry. 293(7)
Epithelial pancreatic acinar cells perform crucial functions in food digestion, and acinar cell homeostasis required for secretion of digestive enzymes relies on SNARE-mediated exocytosis. The ubiquitously expressed Sec1/Munc18 protein mammalian unco
Autor:
Sohail Z. Husain, Misty Good, Ping Guo, George K. Gittes, Tanveer A. Javed, Abrahim I. Orabi, Kathryn L. Lemon, Xiangwei Xiao, Swati Sah, Shunqian Jin, Krishna Prasadan
Publikováno v:
Journal of Biological Chemistry. 290:11309-11320
Nuclear factor κB (NF-κB) is an important signaling molecule that plays a critical role in the development of acute pancreatitis. Current methods for examining NF-κB activation involve infection of an adenoviral NF-κB-luciferase reporter into cel
Autor:
Shunqian Jin, Sohail Z. Husain, Thottala Jayaraman, Frances E. Lund, Kamaldeen A. Muili, Abrahim I. Orabi, Tanveer A. Javed
Publikováno v:
Journal of Biological Chemistry. 288:27128-27137
Aberrant Ca(2+) signals within pancreatic acinar cells are an early and critical feature in acute pancreatitis, yet it is unclear how these signals are generated. An important mediator of the aberrant Ca(2+) signals due to bile acid exposure is the i
Publikováno v:
Journal of Clinical Gastroenterology. 46:656-661
The association between primary hyperparathyroidism (PHPT) and acute or chronic pancreatitis is controversial. For this reason, we conducted a review of the literature over the past 30 years to explore the relationship between these 2 disorders. Ten
Autor:
Dong Wang, Syeda Maham Mahmood, Yuhuan Luo, Kamaldeen A. Muili, Rayman Choo-Wing, Vijay P. Singh, Abrahim I. Orabi, Jerome Parness, Sheharyar Sarwar, George Perides, Vineet Bhandari, Sohail Z. Husain, Meena Ananthanaravanan
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G1423-G1433
Biliary pancreatitis is the most common etiology for acute pancreatitis, yet its pathophysiological mechanism remains unclear. Ca2+signals generated within the pancreatic acinar cell initiate the early phase of pancreatitis, and bile acids can elicit