Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Abraham Siika"'
Autor:
Victor Riitho, Roisin Connon, Agnes Gwela, Josephine Namusanje, Ruth Nhema, Abraham Siika, Mutsa Bwakura-Dangarembizi, Victor Musiime, James A. Berkley, Alex J. Szubert, Diana M. Gibb, A. Sarah Walker, Nigel Klein, Andrew J. Prendergast
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract One-third of people with HIV in sub-Saharan Africa start antiretroviral therapy (ART) with advanced disease. We investigated associations between immune biomarkers and mortality in participants with advanced HIV randomised to cotrimoxazole o
Externí odkaz:
https://doaj.org/article/ec3236ff775048d9b17003f3e68d0d64
Publikováno v:
Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Key Clinical Message This case highlights the need for thorough clinical examination to rule out Takayasu arteritis (TA) as a cause of stroke in a young asymptomatic East‐African male. Available clinical management guidelines should guide managemen
Externí odkaz:
https://doaj.org/article/2c4d852febf04598acb9b6f0c3ce1606
Autor:
Joan Kiyeng, Constantine Akwanalo, Wilson Sugut, Felix Barasa, Ann Mwangi, Benson Njuguna, Abraham Siika, Rajesh Vedanthan
Publikováno v:
Global Heart, Vol 18, Iss 1, Pp 50-50 (2023)
Background: Sustained arrhythmias are frequently encountered in cardiac care units (CCU), but their types and outcomes in Africa are unknown. Studies from high-income countries suggest arrhythmias are associated with worse outcomes. Objectives: To de
Externí odkaz:
https://doaj.org/article/6148e8385ade4837b6ea462f79d694fe
Autor:
Cissy Kityo, Alexander J Szubert, Abraham Siika, Robert Heyderman, Mutsa Bwakura-Dangarembizi, Abbas Lugemwa, Shalton Mwaringa, Anna Griffiths, Immaculate Nkanya, Sheila Kabahenda, Simon Wachira, Godfrey Musoro, Chatu Rajapakse, Timothy Etyang, James Abach, Moira J Spyer, Priscilla Wavamunno, Linda Nyondo-Mipando, Ennie Chidziva, Kusum Nathoo, Nigel Klein, James Hakim, Diana M Gibb, A Sarah Walker, Sarah L Pett, REALITY trial team
Publikováno v:
PLoS Medicine, Vol 15, Iss 12, p e1002706 (2018)
BackgroundIn sub-Saharan Africa, individuals infected with HIV who are severely immunocompromised have high mortality (about 10%) shortly after starting antiretroviral therapy (ART). This group also has the greatest risk of morbidity and mortality as
Externí odkaz:
https://doaj.org/article/58c232363de740f49929ba0af610abb9
Autor:
Tina S Skinner-Adams, Alice S Butterworth, Kimberly A Porter, Ronald D'Amico, Fred Sawe, Doug Shaffer, Abraham Siika, Mina C Hosseinipour, Elizabeth Stringer, Judith S Currier, Tsungai Chipato, Robert Salata, Shahin Lockman, Joseph J Eron, Steven R Meshnick, James S McCarthy
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34399 (2012)
HIV protease inhibitors (PIs) show antimalarial activity in vitro and in animals. Whether this translates into a clinical benefit in HIV-infected patients residing in malaria-endemic regions is unknown. We studied the incidence of malaria, as defined
Externí odkaz:
https://doaj.org/article/e99ee49aba3447378d91bc184440e641
Autor:
April J. Bell, Kara Wools-Kaloustian, Sylvester Kimaiyo, Hai Liu, Adrian Katschke, Changyu Shen, Gilbert Simiyu, Beverly S. Musick, John E. Sidle, Abraham Siika, Paula Braitstein
Publikováno v:
AIDS Research and Treatment, Vol 2012 (2012)
Background. There was a 6-month shortage of antiretrovirals (cART) in Kenya. Methods. We assessed morbidity, mortality, and loss to follow-up (LTFU) in this retrospective analysis of adults who were enrolled during the six-month period with restricte
Externí odkaz:
https://doaj.org/article/52af039829554ae0b85c94a76165e7d4
Autor:
Juddy Wachira, Becky Genberg, Ann Mwangi, Diana Chemutai, Paula Braitstein, Omar Galarraga, Abraham Siika, Ira Wilson
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 90:434-439
Effective patient-centered interventions are needed to promote patient engagement in HIV care. We assessed the impact of a patient-centered intervention referred to as enhanced patient care (EPC) on viral suppression among unsuppressed patients livin
Autor:
Nicholas I Paton, Joseph Musaazi, Cissy Kityo, Stephen Walimbwa, Anne Hoppe, Apolo Balyegisawa, Jesca Asienzo, Arvind Kaimal, Grace Mirembe, Abbas Lugemwa, Gilbert Ategeka, Margaret Borok, Henry Mugerwa, Abraham Siika, Eva Laker A Odongpiny, Barbara Castelnuovo, Agnes Kiragga, Andrew Kambugu, Daniel Kiiza, John Kisembo, John Nsubuga, Max Okwero, Rhona Muyise, Claire Nasaazi, Dridah L. Nakiboneka, Josephine Namusanje, Theresa Najjuuko, Timothy Masaba, Timothy Serumaga, Adolf Alinaitwe, Allan Arinda, Angela Rweyora, Mary Goretti Kangah, Mariam Kasozi, Phionah Tukumushabe, Rogers Akunda, Shafic Makumbi, Sharif Musumba, Sula Myalo, John Ahuura, Annet Mary Namusisi, Daniel Kibirige, Francis Kiweewa, Habert Mabonga, Joseph Wandege, Josephine Nakakeeto, Sharon Namubiru, Winfred Nansalire, Abraham Mosigisi Siika, Charles Meja Kwobah, Chris Sande Mboya, Martha Mokeira Bisieri Mokaya, Mercy Jelagat Karoney, Priscilla Chepkorir Cheruiyot, Salinah Cherutich, Simon Wachira Njuguna, Viola Cherotich Kirui, Ennie Chidziva, Godfrey Musoro, James Hakim, Joyline Bhiri, Misheck Phiri, Shepherd Mudzingwa, Tadios Manyanga, Anchilla Mary Banegura, Betty Agwang, Brian Isaaya, Constantine Tumwine, Eva Laker A. Odongpiny, Nicholas Paton, Peter Senkungu, Yvonne Kamara, Mathius Amperiize, Elizabeth Allen, Charles Opondo, Perry Mohammed, Willemijn van Rein-van der Horst, Yvon Van Delft, Fafa Addo Boateng, Doreen Namara, Pontiano Kaleebu, Sylvia Ojoo, Tapiwanashe Bwakura, Milly Katana, Francois Venter, Sam Phiri, Sarah Walker
Publikováno v:
The Lancet HIV. 9:e381-e393
WHO guidelines recommend dolutegravir plus two nucleoside reverse transcriptase inhibitors (NRTIs) for second-line HIV therapy, with NRTI switching from first-line tenofovir to zidovudine. We aimed to examine whether dolutegravir is non-inferior to d
Autor:
Cathy Toroitich-Ruto, Violet Naanyu, Monicah Nyambura, Thomas J. Spira, Constantin T. Yiannoutsos, Boaz Otieno-Nyunya, Kara Wools-Kaloustian, Abraham Siika, Ann Mwangi, Suzanne Goodrich, Moses Bateganya
Publikováno v:
J Acquir Immune Defic Syndr
OBJECTIVE To develop and assess an alternative care model using community-based groups for people living with HIV and facilitate by lay personnel. METHODS Geographic locations in the Academic Model Providing Access to Healthcare Kitale clinic catchme
Autor:
Henry Mugerwa, Abraham Siika, Agnes Kiragga, Anne Hoppe, Arvind Kaimal, Grace Mirembe, Jesca Asienzo, Stephen Walimbwa, Nadia Trial Team, James Hakim, Andrew Kambugu, Apolo Balyegisawa, Cissy Kityo, Joseph Musaazi, Nicholas I. Paton, Gilbert Ategeka, Barbara Castelnuovo, Phionah Tukamushabe
Publikováno v:
The New England journal of medicine. 385(4)
The World Health Organization recommends dolutegravir with two nucleoside reverse-transcriptase inhibitors (NRTIs) for second-line treatment of human immunodeficiency virus type 1 (HIV-1) infection. Evidence is limited for the efficacy of this regime