Výsledky vyhledávání - "Abraham S. Behrmann"

Abstract 562: Altered Hippo Pathway Activity And Impaired Smooth Muscle Contractile Phenotype In Wnt16-Deficient Mice Worsens Ascending Aortic Aneurysm

Autor: Abraham S Behrmann, Dalian Zhong, Li Li, Shangkui Xie, Mohammad Goodarzi, Andrew Lemoff, Julia Kozlitina, Dwight A Towler

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 42

Wnt16 is expressed in mouse & human vascular smooth muscle (VSM). We assessed the impact of Wnt16 deficiency on angiotensin-II (AngII) -induced aneurysmal remodeling. AngII infusion for 4 weeks increased aortic Wnt16 2-fold & ascending thoracic aorta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::227c3e6527146c2f8172f1c1ea6b30df
https://doi.org/10.1161/atvb.42.suppl_1.562

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Abstract 130: Wnt16 Deficiency Worsens Angiotensin Ii - Induced Aneurysmal Remodeling Of Ascending Thoracic Aorta

Autor: Abraham S Behrmann, Dalian Zhong, Li Li, Parastoo Sabaeifard, Mohammad Goodarzi, Andrew Lemoff, Dwight A Towler

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 41

Wnt16 controls bone strength via paracrine osteoblast-osteoclast remodeling interactions. Wnt16 mRNA is highly expressed in both aorta & bone, & immunofluorescence (IF) localized Wnt16 to vascular smooth muscle (VSM). Paracrine VSM - monocyte/macroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50d9ae500ac8ec28f94dc0f640454178
https://doi.org/10.1161/atvb.41.suppl_1.130

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A GTPase-activating protein–binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells

Autor: Bindu Ramachandran, John N. Stabley, Su-Li Cheng, Abraham S. Behrmann, Austin Gay, Li Li, Megan Mead, Julia Kozlitina, Andrew Lemoff, Hamid Mirzaei, Zhijian Chen, Dwight A. Towler

Publikováno v: Journal of Biological Chemistry. 293:7942-7968

In aortic vascular smooth muscle (VSM), the canonical Wnt receptor LRP6 inhibits protein arginine (Arg) methylation, a new component of noncanonical Wnt signaling that stimulates nuclear factor of activated T cells (viz. NFATc4). To better understand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af68f0a9ad801530bae14c886cb3210
https://doi.org/10.1074/jbc.ra118.002046

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