Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Abraham Madariaga Mazón"'
Autor:
Maciel Rosas-Cruz, Abraham Madariaga Mazón, Carlos D. García-Mejía, Eduardo Hernández-Vázquez, Homero Gómez-Velasco, Eva Jiménez-Faraco, Roberto Sealtiel Farías-Gaytán, Juan A. Hermoso, Siseth Martínez-Caballero
Publikováno v:
ACS Omega, Vol 9, Iss 46, Pp 46461-46471 (2024)
Externí odkaz:
https://doaj.org/article/6ac3b4b25d0f4a499798e46081b249b1
Autor:
Abraham Madariaga-Mazón, José J. Naveja, Arturo Becerra, José Alberto Campillo-Balderas, Ricardo Hernández-Morales, Rodrigo Jácome, Antonio Lazcano, Karina Martinez-Mayorga
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5181-5192 (2022)
The rapid spread and public health impact of the novel SARS-CoV-2 variants that cause COVID-19 continue to produce major global impacts and social distress. Several vaccines were developed in record time to prevent and limit the spread of the infecti
Externí odkaz:
https://doaj.org/article/05a31fa3cef24c1f93d5044e58cb78ad
Publikováno v:
SN Applied Sciences, Vol 3, Iss 5, Pp 1-16 (2021)
Abstract G-protein-biased agonism of the mu-opioid receptor (μ-OR) is emerging as a promising strategy in analgesia. A deep understanding of how biased agonists modulate and differentiate G-protein-coupled receptors (GPCR) signaling pathways and how
Externí odkaz:
https://doaj.org/article/6f781fbad40d49acaca8e3e14515a515
Autor:
Adel Nefzi, Fernando Cosme-Vela, R. Bruno Hernández-Alvarado, Andrés F. Marmolejo-Valencia, Karina Martinez-Mayorga, Abraham Madariaga-Mazón
Publikováno v:
Journal of Computer-Aided Molecular Design. 35:1081-1093
Opioids are potent painkillers, however, their therapeutic use requires close medical monitoring to diminish the risk of severe adverse effects. The G-protein biased agonists of the μ-opioid receptor (MOR) have shown safer therapeutic profiles than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d301ee357da5f8bbd6d0a29d41fa3381
https://doi.org/10.1007/s10822-021-00422-5
https://doi.org/10.1007/s10822-021-00422-5
Publikováno v:
SN Applied Sciences, Vol 3, Iss 5, Pp 1-16 (2021)
Abstract G-protein-biased agonism of the mu-opioid receptor (μ-OR) is emerging as a promising strategy in analgesia. A deep understanding of how biased agonists modulate and differentiate G-protein-coupled receptors (GPCR) signaling pathways and how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6eeb051d287269a8fb2539cb81787ea
https://doaj.org/article/6f781fbad40d49acaca8e3e14515a515
https://doaj.org/article/6f781fbad40d49acaca8e3e14515a515
Autor:
Julio Granados-Montiel, Karina Martinez-Mayorga, Marco Maradiaga-Ceceña, Francisco J. Flores-Murrieta, Víctor Duarte Alaniz, Abraham Madariaga-Mazón, Jazmín García-Morales, Maricruz Maldonado-Rodriguez, J. Jesús Naveja, Juan Pablo Senosiain-Peláez
Publikováno v:
Drug Discovery Today
Graphical abstract
Highlights • Treatment for moderately ill COVID-19 patients might arise from drug repurposing • RdRp, spike protein, and Mpro are relevant SARS-CoV-2 molecular targets. • Targeting human furin may contain viral infection
Highlights • Treatment for moderately ill COVID-19 patients might arise from drug repurposing • RdRp, spike protein, and Mpro are relevant SARS-CoV-2 molecular targets. • Targeting human furin may contain viral infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2781b5517dface0642fff3a241437eee
https://doi.org/10.1016/j.drudis.2020.10.018
https://doi.org/10.1016/j.drudis.2020.10.018
Autor:
Araceli Pérez-Vásquez, Miriam Díaz-Rojas, Erika V. Castillejos-Ramírez, Alejandra Pérez-Esquivel, Yullet Montaño-Cruz, Isabel Rivero-Cruz, Rafael Torres-Colín, Martin González-Andrade, Rogelio Rodríguez-Sotres, José Alberto Gutiérrez-González, Abraham Madariaga-Mazón, Rachel Mata
Publikováno v:
Phytochemistry. 203
An infusion from the aerial parts of Justicia spicigera Schltdl., an herb commonly used to treat diabetes, inhibited the activity of protein tyrosine phosphatase 1B (PTP1B). Two undescribed compounds, 2-N-(p-coumaroyl)-3H-phenoxazin-3-one, and 3″-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3daa6208d6b779f6e0fa2fffd0fc05bb
https://pubmed.ncbi.nlm.nih.gov/36030904
https://pubmed.ncbi.nlm.nih.gov/36030904
Autor:
Alfredo Ortega, Karina Martinez-Mayorga, Abraham Madariaga-Mazón, R. Bruno Hernández-Alvarado
Publikováno v:
ACS Chemical Neuroscience. 11:3979-3992
Salvinorin A is the main bioactive compound in Salvia divinorum, an endemic plant with ancestral use by the inhabitants of the Mazateca mountain range (Sierra Mazateca) in Oaxaca, Mexico. The main use of la pastora, as locally known, is in spiritual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3909cd83b43117b8037249962a6464
https://doi.org/10.1021/acschemneuro.0c00608
https://doi.org/10.1021/acschemneuro.0c00608
Publikováno v:
Expert Opinion on Drug Discovery. 15:293-306
Introduction: Even though there have been substantial advances in our understanding of biological systems, research in drug discovery is only just now beginning to utilize this type of information. The single-target paradigm, which exemplifies the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16ef206d4852f564170cf7477b6051d
https://doi.org/10.1080/17460441.2020.1696307
https://doi.org/10.1080/17460441.2020.1696307
Autor:
Lucas Paul, Boris D. Bekono, Fatima Baldo, Ricardo Bruno Hernández-Alvarado, Celestin Nzanzu Mudogo, Ramsay Soup Teoua Kamdem, Conrad V. Simoben, Abdurrahman Olğaç, Abraham Madariaga-Mazón, Daniel M. Shadrack, Karina Martinez-Mayorga, Wolfgang Sippl, Donatus B. Eni, Fidele Ntie-Kang, Daniel Svozil, Abdulkarim Najjar, Dina Robaa, Sergi Herve Akone, José L. Medina-Franco
Publikováno v:
Advanced Concepts and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99886faf0a0d4d2da8123159af43a792
https://doi.org/10.1515/9783110668896-015
https://doi.org/10.1515/9783110668896-015
