Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Abraham Hochberg"'
Autor:
Abraham Hochberg, Abraham Czerniak, Nathan De Groot, Michal Gilon, Eitan Gershtain, Patricia Ohana, Rasha Abu Lail, Eli Raveh, Imad Matouk
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 4298-4316 (2013)
The field of the long non-coding RNA (lncRNA) is advancing rapidly. Currently, it is one of the most popular fields in the biological and medical sciences. It is becoming increasingly obvious that the majority of the human transcriptome has little or
Externí odkaz:
https://doaj.org/article/11f134d431a5460388c75be427039dc6
Autor:
Imad J Matouk, Nathan DeGroot, Shaul Mezan, Suhail Ayesh, Rasha Abu-lail, Abraham Hochberg, Eithan Galun
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e845 (2007)
BackgroundMutations and epigenetic aberrant signaling of growth factors pathways contribute to carcinogenesis. Recent studies reveal that non-coding RNAs are controllers of gene expression. H19 is an imprinted gene that demonstrates maternal monoalle
Externí odkaz:
https://doaj.org/article/378ee2ae8c694af2bcfd92b1294f4a99
Publikováno v:
Theoretical biology forum. 112(1-2)
To date, classical deterministic Newtonian physics has been used by biologists to describe living processes. However, it is increasingly appreciated that the probabilistic view offered by quantum mechanics more accurately describes the behavior of at
Autor:
Vladimir Shulaev, Luhua Song, Ron Mittler, Sarah H. Holt, Abraham Hochberg, Yang Sung Sohn, Rachel Nechushtai, José N. Onuchic, Andrea R. Conlan, Dorit Michaeli, Yael Harir, Imad Matouk, Sagi Tamir, Ioav Z. Cabanchick, Patricia A. Jennings, Mark L. Paddock
Publikováno v:
Proceedings of the National Academy of Sciences. 110:14676-14681
Mitochondria are emerging as important players in the transformation process of cells, maintaining the biosynthetic and energetic capacities of cancer cells and serving as one of the primary sites of apoptosis and autophagy regulation. Although sever
Publikováno v:
Seminars in Oncology. 39:534-542
The purpose of this review is to demonstrate a successful use of preclinical models of bladder cancer to confirm the therapeutic potential of new promising drug candidates. The bladder has long been thought to be an ideal target for investigating the
Autor:
Ayala Hubert, Patricia Ohana, Abraham Hochberg, L Appelbaum, G Leichtmann, Abraham Czerniak, Y Kopelman, F. Konikoff, Nader Hanna
Publikováno v:
Cancer Gene Therapy. 19:374-381
BC-819 is a DNA plasmid that was developed to target the expression of diphtheria-toxin gene under the control of H19 regulatory sequences. BC-819 has the potential to treat pancreatic cancer that overexpresses the H19 gene. The objectives were to as
Autor:
Patricia Ohana, Imad Matouk, Yakov Fellig, Aya Mizrahi, Shaul Mezan, Nathan de-Groot, Rasha Abu-lail, Eithan Galun, Abraham Hochberg
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1803(4):443-451
Expression of the imprinted H19 gene is remarkably elevated in a large number of human cancers. Recently, we reported that H19 RNA is up-regulated in hypoxic stress and furthermore, it possesses oncogenic properties. However, the underlying mechanism
Publikováno v:
Journal of Translational Medicine
Since it was first described, the imprinted cluster 11p15.5 has been reported to be deregulated in a variety of pediatric and adult cancers including that of the lung. Both protein coding and non-coding genes functioning as oncogenes or as tumor supp
Autor:
Patricia Ohana, Tatiana Birman, Abraham Hochberg, Ofrer N. Gofrit, Suhail Ayesh, Anna Dinaburg
Publikováno v:
Urology. 68:231-235
Objectives Carcinogen-induced bladder cancer in rodents is a key model for evaluation of novel therapies for bladder cancer because of its similarity to the clinical disease. The major drawback of the model is the difficulty in assessing tumor burden
Autor:
Ilana Ariel, Abraham Hochberg, Yaron Hamani, Wasif Al-Shareef, Eyal Y. Anteby, Tamar Schneider, Suhail Ayesh, Mara Shochina
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 118:174-181
Objectives: To screen for genes with altered expression in placentas from pregnancies complicated by preeclampsia. Study design: To corroborate gene expression profile of preeclamptic and normal placentas (ATLAS™ Clontech), by dot blot, Northern bl