Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Abraham Fainsod"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Neural tube defects (NTDs) are among the most debilitating and common developmental defects in humans. The induction of NTDs has been attributed to abnormal folic acid (vitamin B9) metabolism, Wnt and BMP signaling, excess retinoic acid
Externí odkaz:
https://doaj.org/article/78671b6d61364fc29563005f04121777
Autor:
Leo McKay, Berardino Petrelli, Molly Pind, James N. Reynolds, Richard F. Wintle, Albert E. Chudley, Britt Drögemöller, Abraham Fainsod, Stephen W. Scherer, Ana Hanlon-Dearman, Geoffrey G. Hicks
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 569 (2024)
Fetal Alcohol Spectrum Disorder (FASD) is a common neurodevelopmental disorder that affects an estimated 2–5% of North Americans. FASD is induced by prenatal alcohol exposure (PAE) during pregnancy and while there is a clear genetic contribution, f
Externí odkaz:
https://doaj.org/article/d3ecba3d3c3041e2b9255bc61b22cafc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Retinoic acid (RA) is a central regulatory signal that controls numerous developmental processes in vertebrate embryos. Although activation of Hox expression is considered one of the earliest functions of RA signaling in the embryo, there is evidence
Externí odkaz:
https://doaj.org/article/5412626c186c4dc885df80098a40ab98
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Retinoic acid (RA) is a central signaling molecule regulating multiple developmental decisions during embryogenesis. Excess RA induces head malformations, primarily by expansion of posterior brain structures at the expense of anterior head regions, i
Externí odkaz:
https://doaj.org/article/198c67940d5d47398c1b6d4b9e4a456e
Autor:
Madhur Parihar, Liat Bendelac-Kapon, Michal Gur, Tali Abbou, Abha Belorkar, Sirisha Achanta, Keren Kinberg, Rajanikanth Vadigepalli, Abraham Fainsod
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Robustness is a feature of regulatory pathways to ensure signal consistency in light of environmental changes or genetic polymorphisms. The retinoic acid (RA) pathway, is a central developmental and tissue homeostasis regulatory signal, strongly depe
Externí odkaz:
https://doaj.org/article/f1794033bcd646a6a97139a9f24fb05a
Publikováno v:
Cells, Vol 11, Iss 3, p 327 (2022)
Retinoic acid (RA) is a major regulatory signal during embryogenesis produced from vitamin A (retinol) by an extensive, autoregulating metabolic and signaling network to prevent fluctuations that result in developmental malformations. Xenopus laevis
Externí odkaz:
https://doaj.org/article/a0df5c8af485460abee315678327c64a
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background The bone morphogenetic protein (BMP) signaling gradient is central for dorsoventral patterning in amphibian embryos. This gradient is established through the interaction of several BMPs and BMP antagonists and modulators, some sec
Externí odkaz:
https://doaj.org/article/de50422fe0d544d59ee5caa68ad1de53
Autor:
Marta Vitorino, Ana Cristina Silva, José Manuel Inácio, José Silva Ramalho, Michal Gur, Abraham Fainsod, Herbert Steinbeisser, José António Belo
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135504 (2015)
Protein Kinase Domain Containing, Cytoplasmic (PKDCC) is a protein kinase which has been implicated in longitudinal bone growth through regulation of chondrocytes formation. Nevertheless, the mechanism by which this occurs remains unknown. Here, we i
Externí odkaz:
https://doaj.org/article/5fd93be4fcaa495d96ec37dd570b4343
Autor:
Abraham Fainsod, Sally A. Moody
This book focuses on the amphibian, Xenopus, one of the most commonly used model animals in the biological sciences. Over the past 50 years, the use of Xenopus has made possible many fundamental contributions to our knowledge in cell biology, develop
Publikováno v:
Xenopus ISBN: 9781003050230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b510f94b14fd49efff50674e2fcf921
https://doi.org/10.1201/9781003050230-25
https://doi.org/10.1201/9781003050230-25