Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Abraham E. Mathew"'
Publikováno v:
Natural Product Communications. 8:1934578X1300800
The current study is directed at identifying compounds that have biological activity in the less studied oil fraction of Curcuma longa (turmeric) to treat pancreatic cancer, which has no good treatment options. Fractional distillation and chromatogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3bb84e41fbcb056d63fa4480e0de8d
https://doi.org/10.1177/1934578x1300800633
https://doi.org/10.1177/1934578x1300800633
Autor:
Jyoti P. Nath, Richard H. Himes, Abraham E. Mathew, Valentino J. Stella, Magdalena R. Mejillano
Publikováno v:
Journal of medicinal chemistry. 35(1)
The synthesis and evaluation of some 2'- and 7-amino acid derivatives of taxol (1) are reported. Reaction of taxol with N-protected amino acids gave 2'-N-protected amino acid esters of taxol. However, deprotection of the amino group and subsequent is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26abcc97dea1909aa265ebe9627f5e1
https://pubmed.ncbi.nlm.nih.gov/1346275
https://pubmed.ncbi.nlm.nih.gov/1346275
Publikováno v:
Journal of Medicinal Chemistry. 29:1792-1795
Based on the observation of outstanding antineoplastic activity of a number of amino-substituted anthraquinones, thioxanthones, and N-(aminoethyl)-substituted naphthalimides, four types of amino-substituted p-benzoquinones were designed, synthesized,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9c6f4da21dadecc7d129654ca07aad
https://doi.org/10.1021/jm00159a041
https://doi.org/10.1021/jm00159a041
Publikováno v:
Journal of Medicinal Chemistry. 30:1682-1686
A number of chloro-substituted [(aminoalkyl)amino]anthraquinones were synthesized and evaluated for their antineoplastic and cytotoxic activity. Treatment of 5,8-dichloroquinizarin with substituted amines in pyridine resulted in the replacement of on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8c8101609d701bca260f4be5ee0ac6
https://doi.org/10.1021/jm00392a028
https://doi.org/10.1021/jm00392a028
Autor:
Abraham E. Mathew, John R. Dodd
Publikováno v:
Journal of Heterocyclic Chemistry. 22:225-228
The synthesis of derivatives of 2,2,5,5-tetramethylpyrrolidine nitroxide spin labels as pH sensitive probes is reported. The data on the pH sensitivity studies of these compounds indicate that the amino group increases the pH sensitivity of a nitroxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef19f7abfdb7a1efffc66506f608c0ea
https://doi.org/10.1002/jhet.5570220153
https://doi.org/10.1002/jhet.5570220153
Autor:
J.R. Dodd, Abraham E. Mathew
Publikováno v:
Steroids. 42:241-247
An improved synthesis of spin-labeled cortisol, cortisone, and testosterone using N, N'-cyclohexylcarbodiimide (DCC) is reported. The spin labeled steroids are shown to result from the esterification at the most reactive C(21) and C(17) hydroxyl grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92d9873906c6bdeb4de19f186572a9b
https://doi.org/10.1016/0039-128x(83)90036-3
https://doi.org/10.1016/0039-128x(83)90036-3
Publikováno v:
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. 37:315-319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280d84da2ee30286a23a9f627f41febc
https://doi.org/10.1080/09553008014550361
https://doi.org/10.1080/09553008014550361
Publikováno v:
ChemInform. 18
Based on the observation of outstanding antineoplastic activity of a number of amino-substituted anthraquinones, thioxanthones, and N-(aminoethyl)-substituted naphthalimides, four types of amino-substituted p-benzoquinones were designed, synthesized,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62e737a171a747c2039e203846b038dd
https://doi.org/10.1002/chin.198707166
https://doi.org/10.1002/chin.198707166
Autor:
Abraham E. Mathew, C.C. Cheng
Publikováno v:
Tetrahedron Letters. 25:269-270
Synthesis of spin labeled analogs of antineoplastic dihydroxyaminoalkylaminoanthraquinones is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6775eac1c1945839331d72e4e67176a
https://doi.org/10.1016/s0040-4039(00)99858-7
https://doi.org/10.1016/s0040-4039(00)99858-7
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :222
Two novel spin-labelled cis-platinum drugs have been synthesized and allowed to react with deoxyguanosine to form a spin-labelled complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e3c7a7219b7bb1295abe8602abfc422
https://doi.org/10.1039/c39790000222
https://doi.org/10.1039/c39790000222