Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Abraham C. I. van Steen"'
Autor:
Kim C. M. Jeucken, Charlotte C. N. van Rooijen, Yik Y. Kan, Lotte A. Kocken, Aldo Jongejan, Abraham C. I. van Steen, Jaap D. van Buul, Henric K. Olsson, Jan Piet van Hamburg, Sander W. Tas
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Endothelial cells (ECs) are important contributors to inflammation in immune-mediated inflammatory diseases (IMIDs). In this study, we examined whether CD4+ memory T (Tm) cells can drive EC inflammatory responses. Human Tm cells produced ligands that
Externí odkaz:
https://doaj.org/article/611aa83d146b4cf1828eb31ebc7b2cf4
Autor:
Lanette Kempers, Evelien G. G. Sprenkeler, Abraham C. I. van Steen, Jaap D. van Buul, Taco W. Kuijpers
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The actin-related protein (ARP) 2/3 complex, essential for organizing and nucleating branched actin filaments, is required for several cellular immune processes, including cell migration and granule exocytosis. Recently, genetic defects in ARPC1B, a
Externí odkaz:
https://doaj.org/article/553203ee1202459bbdfa4f05acd16fda
Autor:
Max L B Grönloh, Janine J G Arts, Sebastián Palacios Martínez, Amerens A van der Veen, Lanette Kempers, Abraham C I van Steen, Joris J T H Roelofs, Martijn A Nolte, Joachim Goedhart, Jaap D van Buul
Publikováno v:
Grönloh, M L B, Arts, J J G, Palacios Martínez, S, van der Veen, A A, Kempers, L, van Steen, A C I, Roelofs, J J T H, Nolte, M A, Goedhart, J & van Buul, J D 2023, ' Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM-1 ', EMBO Reports, vol. 24, no. 1, e55483 . https://doi.org/10.15252/embr.202255483
EMBO reports, 24(1):e55483. Wiley-Blackwell
EMBO Reports, 24(1):e55483. Wiley-Blackwell
EMBO reports, 24(1):e55483. Wiley-Blackwell
EMBO Reports, 24(1):e55483. Wiley-Blackwell
Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration ‘hotspot’ regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that endot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668e948a7eee2654f8daa2c0cb6818aa
https://research.vumc.nl/en/publications/977802a3-56bf-40d5-8031-092edf437de6
https://research.vumc.nl/en/publications/977802a3-56bf-40d5-8031-092edf437de6