Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Abraham Al Ahmad"'
Autor:
Douglas N Clarke, Abraham Al Ahmad, Boyeon Lee, Christi Parham, Lisa Auckland, Andrezj Fertala, Michael Kahle, Courtney S Shaw, Jill Roberts, Gregory J Bix
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45257 (2012)
Perlecan Domain V (DV) promotes brain angiogenesis by inducing VEGF release from brain endothelial cells (BECs) following stroke. In this study, we define the specific mechanism of DV interaction with the α(5)β(1) integrin, identify the downstream
Externí odkaz:
https://doaj.org/article/985775c1dbe244669038b389ed968ffa
Autor:
Behnam Noorani, Ekram Ahmed Chowdhury, Faleh Alqahtani, Yeseul Ahn, Dhavalkumar Patel, Abraham Al-Ahmad, Reza Mehvar, Ulrich Bickel
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Understanding the pathophysiology of the blood brain–barrier (BBB) plays a critical role in diagnosis and treatment of disease conditions. Applying a sensitive and specific LC–MS/MS technique for the measurement of BBB integri
Externí odkaz:
https://doaj.org/article/78f27fe894c145a39c0f6f93663ccadf
Autor:
Behnam Noorani, Ekram Ahmed Chowdhury, Faleh Alqahtani, Yeseul Ahn, Ehsan Nozohouri, Sumaih Zoubi, Dhavalkumar Patel, Laurence Wood, Juyang Huang, Muhammad Bilal Siddique, Abraham Al-Ahmad, Reza Mehvar, Ulrich Bickel
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 385:135-145
Autor:
Behnaz Lahooti, Racheal G. Akwii, Dhavalkumar Patel, Siavash ShahbaziNia, Margarita Lamprou, Mahboubeh Madadi, Thomas J. Abbruscato, Aristotelis Astrinidis, Ulrich Bickel, Abraham Al-Ahmad, Nadezhda A. German, George Mattheolabakis, Constantinos M. Mikelis
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 385:35-49
Autor:
Vincent L. Cryns, Carey K. Anders, Eric V. Shusta, Lisa Carey, Matt Ewend, Joseph Geradts, Kimberly Blackwell, Erika Hamilton, Karen Fritchie, Chad Livasy, Andrey Ugolkov, C. Ryan Miller, Barbara Adamo, Abraham Al Ahmad, Allison M. Deal, Vladimir Petrovic, Elena Strekalova, Dmitry Malin
PDF file - 797K, Figure S1. Barrier phenotype of human brain microvascular endothelial cells and astrocytes in monocultures and co-cultures. Figure S2. alpha/beta-crystallin does not affect cell viability of TNBC cells in standard monolayer culture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037114286fb81617e95760c4df77ea6b
https://doi.org/10.1158/1078-0432.22450124
https://doi.org/10.1158/1078-0432.22450124
Autor:
Vincent L. Cryns, Carey K. Anders, Eric V. Shusta, Lisa Carey, Matt Ewend, Joseph Geradts, Kimberly Blackwell, Erika Hamilton, Karen Fritchie, Chad Livasy, Andrey Ugolkov, C. Ryan Miller, Barbara Adamo, Abraham Al Ahmad, Allison M. Deal, Vladimir Petrovic, Elena Strekalova, Dmitry Malin
Purpose: Basal-like breast tumors are typically (ER/PR/HER2) triple-negative and are associated with a high incidence of brain metastases and poor clinical outcomes. The molecular chaperone αB-crystallin is predominantly expressed in triple-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266e61780d81213be1d293febd4331de
https://doi.org/10.1158/1078-0432.c.6521858
https://doi.org/10.1158/1078-0432.c.6521858
Autor:
Jérôme Barrière, Fabrice Frank, Lonni Besançon, Alexander Samuel, Véronique Saada, Eric Billy, Abraham Al-Ahmad, Barbara Seitz-Polski, Jacques Robert
Publikováno v:
Stem cell reviews and reports.
Recently, an article by Seneff et al. entitled "Innate immunosuppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs" was published in Food and Chemical Toxicology (FCT). Here, we describe why this article, wh
Autor:
Xiaojun Lian, Xiaoping Bao, Abraham Al-Ahmad, Jialu Liu, Yue Wu, Wentao Dong, Kaitlin K. Dunn, Eric V. Shusta, Sean P. Palecek
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 804-816 (2014)
Human pluripotent stem cell (hPSC)-derived endothelial cells and their progenitors may provide the means for vascularization of tissue-engineered constructs and can serve as models to study vascular development and disease. Here, we report a method t
Externí odkaz:
https://doaj.org/article/b677258a9e584a88be1056fb2d83dda8
CNS organoids: an innovative tool for neurological disease modeling and drug neurotoxicity screening
Autor:
Tanya Chhibber, Sounak Bagchi, Gurudutt Pendyala, Rahul Dev Jayant, Manash K. Paul, Behnaz Lahooti, Abraham Al-Ahmad, Angela Verma
Publikováno v:
Drug Discov Today
The paradigm of central nervous system (CNS) drug discovery has mostly relied on traditional approaches of rodent models or cell-based in vitro models. Owing to the issues of species differences between humans and rodents, it is difficult to correlat
Publikováno v:
NeuroMolecular Medicine. 21:414-431
The blood-brain barrier (BBB) plays an important role in brain homeostasis. Hypoxia/ischemia constitutes an important stress factor involved in several neurological disorders by inducing the disruption of the BBB, ultimately leading to cerebral edema