UPLC-HRMS/MS Guided Isolation and NMR Investigation of Major Flavonoids from Enarthrocarpus strangulatus Boissier (Brassicaceae) with In Vitro Enzymes Inhibitory Potential.

Autor: Hegazi N; National Research Centre, Phytochemistry and Plant Systematics, 33 elbouhoth, 12622, cairo, Egypt, EGYPT., El Shabrawy MO; National Research Centre, Phytochemistry and Plant Systematics, 33 elbouhoth, 12622, cairo, Egypt, EGYPT., Aboulthana WM; National Research Centre, Biochemistry, 33 elbouhoth, 12622, cairo, Egypt, EGYPT., Yassin A; National Research Centre, Phytochemistry and Plant Systematics, 33 elbouhoth, 12622, cairo, Egypt, EGYPT., Ibrahim LF; National Research Centre, Phytochemistry and Plant Systematics, 33 elbouhoth, 12622, cairo, Egypt, EGYPT., Marzouk M; national research centre, phytochemistry and plant systematics, ei bohoos, Not Available, 12622, Giza, EGYPT.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2024 Oct 06, pp. e202401402. Date of Electronic Publication: 2024 Oct 06.

Explore new quinoxaline pharmacophore tethered sulfonamide fragments as in vitro α-glucosidase, α-amylase, and acetylcholinesterase inhibitors with ADMET and molecular modeling simulation.

Autor: Ragab A; Department of Chemistry, Faculty of Science (boys), Al-Azhar University, Nasr, Cairo, Egypt., Salem MA; Department of Chemistry, Faculty of Science and Arts, King Khalid University, Mohail, Assir, Saudi Arabia., Ammar YA; Department of Chemistry, Faculty of Science (boys), Al-Azhar University, Nasr, Cairo, Egypt., Aboulthana WM; Biochemistry Department, Biotechnology Research Institute, National Research Centre, Dokki, Cairo, Egypt., Helal MH; Department of Chemistry, Faculty of Arts and Science, Northern Border University, Rafha, Saudi Arabia., Abusaif MS; Department of Chemistry, Faculty of Science (boys), Al-Azhar University, Nasr, Cairo, Egypt.

Publikováno v: Drug development research [Drug Dev Res] 2024 Jun; Vol. 85 (4), pp. e22216.

Exploring the Potential Biological Activities of Pyrazole-Based Schiff Bases as Anti-Diabetic, Anti-Alzheimer's, Anti-Inflammatory, and Cytotoxic Agents: In Vitro Studies with Computational Predictions.

Autor: Naglah AM; Drug Exploration and Development Chair (DEDC), Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia., Almehizia AA; Drug Exploration and Development Chair (DEDC), Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia., Al-Wasidi AS; Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia., Alharbi AS; King Khalid Hospital, King Saud University Medical City, P.O. Box 7805, Riyadh 11472, Saudi Arabia., Alqarni MH; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi Arabia., Hassan AS; Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622, Cairo, Egypt., Aboulthana WM; Biochemistry Department, Biotechnology Research Institute, National Research Centre, Dokki 12622, Cairo, Egypt.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 May 17; Vol. 17 (5). Date of Electronic Publication: 2024 May 17.

Synthesis, structural, molecular docking, and in vitro biological activities of Cu-doped ZnO nanomaterials.

Autor: El-Sayed AF; Microbial Genetics Department, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St. (Former El Tahrir St.), P.O. 12622, Dokki, Cairo, Egypt.; Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo, Egypt., Aboulthana WM; Biochemistry Department, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St. (Former El Tahrir St.), P.O. 12622, Dokki, Cairo, Egypt. wmkamel83@hotmail.com., Sherief MA; Inorganic Chemistry Department, Advanced Materials Technology and Mineral Resources Research Institute, National Research Centre, 33 El Bohouth St. (Former El Tahrir St.), P.O. 12622, Dokki, Cairo, Egypt., El-Bassyouni GT; Refractories, Ceramics and Building Materials Department, Advanced Materials Technology and Mineral Resources Research Institute, National Research Centre, 33 El Bohouth St. (Former El Tahrir St.), P.O. 12622, Dokki, Cairo, Egypt., Mousa SM; Inorganic Chemistry Department, Advanced Materials Technology and Mineral Resources Research Institute, National Research Centre, 33 El Bohouth St. (Former El Tahrir St.), P.O. 12622, Dokki, Cairo, Egypt.

Publikováno v: Scientific reports [Sci Rep] 2024 Apr 19; Vol. 14 (1), pp. 9027. Date of Electronic Publication: 2024 Apr 19.

In vitro biological studies and computational prediction-based analyses of pyrazolo[1,5- a ]pyrimidine derivatives.

Autor: Almehizia AA; Drug Exploration & Development Chair (DEDC), Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University Riyadh 11451 Saudi Arabia., Aboulthana WM; Biochemistry Department, Biotechnology Research Institute, National Research Centre Dokki 12662 Cairo Egypt., Naglah AM; Drug Exploration & Development Chair (DEDC), Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University Riyadh 11451 Saudi Arabia., Hassan AS; Organometallic and Organometalloid Chemistry Department, National Research Centre Dokki 12622 Cairo Egypt ashraf_salmoon@yahoo.com as.el-salmoon@nrc.sci.eg.

Publikováno v: RSC advances [RSC Adv] 2024 Mar 12; Vol. 14 (12), pp. 8397-8408. Date of Electronic Publication: 2024 Mar 12 (Print Publication: 2024).