Modeling enzyme competition in Eicosanoid metabolism in macrophage cells using a cybernetic framework.

Autor: Khanum S; The Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN 47907, USA., Gupta S; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA., Maurya MR; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA., Raja R; The Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN 47907, USA., Aboulmouna L; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA., Subramaniam S; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA; Departments of Computer Science and Engineering, Cellular and Molecular Medicine, San Diego Supercomputer Center, and the Graduate Program in Bioinformatics and Systems Biology, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: shsubramaniam@ucsd.edu., Ramkrishna D; The Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN 47907, USA. Electronic address: ramkrish@purdue.edu.

Publikováno v: Journal of lipid research [J Lipid Res] 2024 Oct 10, pp. 100666. Date of Electronic Publication: 2024 Oct 10.

Modeling transcriptional regulation of the cell cycle using a novel cybernetic-inspired approach.

Autor: Raja R, Khanum S, Aboulmouna L, Maurya MR, Gupta S, Subramaniam S, Ramkrishna D

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 23. Date of Electronic Publication: 2023 Mar 23.

Mechanistic Modeling and Analysis of the Mammalian Unfolded Protein Response

Autor: Anirikh Chakrabarti, Aboulmouna L, Jeffery D. Varner

Cells monitor protein folding by an inbuilt quality-control system in which incorrectly or misfolded folded proteins are tagged for degradation or sent back through a refolding cycle. However, continued accumulation of incorrectly folded proteins tri

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Translating weighted probabilistic bits to synthetic genetic circuits.

Autor: Ciccone MD; Department of Horticultural Sciences, University of Florida, Gainesville, Florida, USA.; Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey, USA., Messina CD; Department of Horticultural Sciences, University of Florida, Gainesville, Florida, USA.

Publikováno v: The plant genome [Plant Genome] 2024 Oct 18, pp. e20525. Date of Electronic Publication: 2024 Oct 18.