Zobrazeno 1 - 10 of 469 pro vyhledávání: '"Abou-Ajram C"'
1
Cumulative regulatory potential of clustered methyl-arginine protein modifications
Autor: Woodsmith, J., Casado-Medrano, V., Benlasfer, N., Eccles, R.L., Hutten, S., Heine, C., Thormann, V., Abou-Ajram, C., Rocks, O., Dormann, D., Stelzl, U.
Systematic analysis of human arginine methylation events bifurcates its signaling mechanism, functioning either in isolation akin to canonical PTM regulation or clustered within disordered protein sequence. Hundreds of proteins contain methyl-arginin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=mdc______med::b6d74f7764564c1a173cd1f9fe176469
http://edoc.mdc-berlin.de/17692/1/17692oa.pdf
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2
Akademický článek
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome.
Autor: Krane M; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.)., Dreßen M; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Santamaria G; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., My I; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Schneider CM; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Dorn T; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Laue S; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Mastantuono E; German Heart Center Munich, and Institute of Human Genetics (E.M., R.B., T.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; Helmholtz Zentrum München, Neuherberg, Germany (E.M., R.B., T.M.)., Berutti R; German Heart Center Munich, and Institute of Human Genetics (E.M., R.B., T.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; Helmholtz Zentrum München, Neuherberg, Germany (E.M., R.B., T.M.)., Rawat H; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Gilsbach R; Institute of Experimental and Clinical Pharmacology and Toxicology (R.G., P.S., L.H.), University of Freiburg, Germany.; Institute for Cardiovascular Physiology, Goethe University, Frankfurt am Main, Germany (R.G.).; DZHK (German Centre for Cardiovascular Research)-partner site RheinMain, Frankfurt am Main, Germany (R.G.)., Schneider P; Institute of Experimental and Clinical Pharmacology and Toxicology (R.G., P.S., L.H.), University of Freiburg, Germany., Lahm H; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Schwarz S; Center for Applied Tissue Engineering and Regenerative Medicine (CANTER), Munich University of Applied Sciences, Germany (S. Schwarz, S. Sudhop)., Doppler SA; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Paige S; Cardiovascular Institute, Stanford University School of Medicine, CA (S.P., S.W.)., Puluca N; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Doll S; Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany (S.D., M.M.)., Neb I; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Brade T; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Zhang Z; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Abou-Ajram C; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Northoff B; Institute of Laboratory Medicine (B.N., L.M.H.), University Hospital, LMU Munich, Germany., Holdt LM; Institute of Laboratory Medicine (B.N., L.M.H.), University Hospital, LMU Munich, Germany., Sudhop S; Center for Applied Tissue Engineering and Regenerative Medicine (CANTER), Munich University of Applied Sciences, Germany (S. Schwarz, S. Sudhop)., Sahara M; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden (M.S.)., Goedel A; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Dendorfer A; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).; Walter-Brendel-Centre of Experimental Medicine (A.D.), University Hospital, LMU Munich, Germany., Tjong FVY; Heart Centre, Department of Clinical and Experimental Cardiology, Amsterdam UMC, University of Amsterdam, The Netherlands (F.V.Y.T., C.B.)., Rijlaarsdam ME; Department of Pediatric Cardiology, Leiden University Medical Center, The Netherlands (M.E.R.)., Cleuziou J; Department of Congenital and Paediatric Heart Surgery, Institute Insure (J.C.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Lang N; Department of Paediatric Cardiology and Congenital Heart Defects (N.L.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany., Kupatt C; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.)., Bezzina C; Heart Centre, Department of Clinical and Experimental Cardiology, Amsterdam UMC, University of Amsterdam, The Netherlands (F.V.Y.T., C.B.)., Lange R; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.)., Bowles NE; Department of Pediatrics (Division of Cardiology), University of Utah School of Medicine, Salt Lake City (N.E.B.)., Mann M; Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany (S.D., M.M.)., Gelb BD; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York (B.D.G.)., Crotti L; Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano, IRCCS, Milan, Italy (L.C.).; Cardiomyopathies Unit, Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, San Luca Hospital, Milan, Italy (L.C.).; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (L.C.)., Hein L; Institute of Experimental and Clinical Pharmacology and Toxicology (R.G., P.S., L.H.), University of Freiburg, Germany.; BIOSS, Center for Biological Signaling Studies (L.H.), University of Freiburg, Germany., Meitinger T; German Heart Center Munich, and Institute of Human Genetics (E.M., R.B., T.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).; Helmholtz Zentrum München, Neuherberg, Germany (E.M., R.B., T.M.)., Wu S; Cardiovascular Institute, Stanford University School of Medicine, CA (S.P., S.W.)., Sinnecker D; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.)., Gruber PJ; Department of Surgery, Yale University, New Haven, CT (P.J.G.)., Laugwitz KL; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.)., Moretti A; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).
Publikováno v: Circulation [Circulation] 2021 Oct 26; Vol. 144 (17), pp. 1409-1428. Date of Electronic Publication: 2021 Oct 25.
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3
Akademický článek
Nuclear–Cytoplasmic Shuttling of the Usher Syndrome 1G Protein SANS Differs from Its Paralog ANKS4B.
Autor: Fritze, Jacques S.1 (AUTHOR) jfritze@uni-mainz.de, Stiehler, Felizitas F.1 (AUTHOR), Wolfrum, Uwe1 (AUTHOR) wolfrum@uni-mainz.de
Publikováno v: Cells (2073-4409). Nov2024, Vol. 13 Issue 22, p1855. 24p.
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4
Akademický článek
Potential Mechanisms of Tunneling Nanotube Formation and Their Role in Pathology Spread in Alzheimer's Disease and Other Proteinopathies.
Autor: Kotarba, Szymon1 (AUTHOR) szymon.kotarba@stud.umed.lodz.pl, Kozłowska, Marta1 (AUTHOR) marta.kozlowska1@stud.umed.lodz.pl, Scios, Małgorzata1 (AUTHOR) malgorzata.scios@stud.umed.lodz.pl, Saramowicz, Kamil1 (AUTHOR) kamil.saramowicz@stud.umed.lodz.pl, Barczuk, Julia1 (AUTHOR) julia.barczuk@stud.umed.lodz.pl, Granek, Zuzanna1 (AUTHOR) zuzanna.granek@stud.umed.lodz.pl, Siwecka, Natalia1 (AUTHOR) natalia.siwecka@stud.umed.lodz.pl, Wiese, Wojciech1 (AUTHOR) wojciech.wiese@stud.umed.lodz.pl, Golberg, Michał2 (AUTHOR) michal.golberg@umed.lodz.pl, Galita, Grzegorz1 (AUTHOR) grzegorz.galita@umed.lodz.pl, Sychowski, Grzegorz1 (AUTHOR) grzegorz.sychowski@stud.umed.lodz.pl, Majsterek, Ireneusz1 (AUTHOR) ireneusz.majsterek@umed.lodz.pl, Rozpędek-Kamińska, Wioletta1 (AUTHOR) wioletta.rozpedek@umed.lodz.pl
Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10797. 23p.
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5
Akademický článek
Congenital heart disease risk loci identified by genome-wide association study in European patients.
Autor: Lahm H; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Jia M; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry Munich, Munich, Germany., Dreßen M; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Wirth F; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Puluca N; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Gilsbach R; Institute for Cardiovascular Physiology, Goethe University, Frankfurt am Main, Germany.; DZHK (German Centre for Cardiovascular Research), Partner site RheinMain, Frankfurt am Main, Germany., Keavney BD; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.; Manchester Heart Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom., Cleuziou J; Department of Congenital and Paediatric Heart Surgery, German Heart Center Munich, Munich, Germany., Beck N; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Bondareva O; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Dzilic E; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Burri M; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., König KC; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Ziegelmüller JA; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Abou-Ajram C; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Neb I; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Zhang Z; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Doppler SA; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany., Mastantuono E; Institute of Human Genetics, German Research Center for Environmental Health, Helmholtz Center Munich, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Lichtner P; Institute of Human Genetics, German Research Center for Environmental Health, Helmholtz Center Munich, Neuherberg, Germany., Eckstein G; Institute of Human Genetics, German Research Center for Environmental Health, Helmholtz Center Munich, Neuherberg, Germany., Hörer J; Department of Congenital and Paediatric Heart Surgery, German Heart Center Munich, Munich, Germany., Ewert P; Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Munich, Germany., Priest JR; Department of Pediatrics, Division of Pediatric Cardiology, Stanford University School of Medicine, Palo Alto, California, USA., Hein L; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; BIOSS, Center for Biological Signaling Studies, University of Freiburg, Freiburg, Germany., Lange R; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany.; DZHK (German Center for Cardiovascular Research) - Partner Site Munich Heart Alliance, Munich, Germany., Meitinger T; Institute of Human Genetics, German Research Center for Environmental Health, Helmholtz Center Munich, Neuherberg, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; DZHK (German Center for Cardiovascular Research) - Partner Site Munich Heart Alliance, Munich, Germany., Cordell HJ; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, United Kingdom., Müller-Myhsok B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry Munich, Munich, Germany.; Munich Cluster of Systems Biology, SyNergy, Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom., Krane M; Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich, Munich, Germany.; DZHK (German Center for Cardiovascular Research) - Partner Site Munich Heart Alliance, Munich, Germany.
Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Jan 19; Vol. 131 (2).
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6
Akademický článek
Nonclassical nuclear localization signals mediate nuclear import of CIRBP.
Autor: Bourgeois B; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria., Hutten S; BioMedical Center, Cell Biology, Ludwig Maximilians University Munich, 82152 Planegg-Martinsried, Germany., Gottschalk B; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria., Hofweber M; BioMedical Center, Cell Biology, Ludwig Maximilians University Munich, 82152 Planegg-Martinsried, Germany.; Graduate School of Systemic Neurosciences, 82152 Planegg-Martinsried, Germany., Richter G; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria., Sternat J; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria., Abou-Ajram C; BioMedical Center, Cell Biology, Ludwig Maximilians University Munich, 82152 Planegg-Martinsried, Germany., Göbl C; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria., Leitinger G; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Cell Biology, Histology and Embryology, Medical University of Graz, 8010 Graz, Austria., Graier WF; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria.; BioTechMed-Graz, 8010 Graz, Austria., Dormann D; BioMedical Center, Cell Biology, Ludwig Maximilians University Munich, 82152 Planegg-Martinsried, Germany; dorothee.dormann@med.uni-muenchen.de tobias.madl@medunigraz.at.; Graduate School of Systemic Neurosciences, 82152 Planegg-Martinsried, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Madl T; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, 8010 Graz, Austria; dorothee.dormann@med.uni-muenchen.de tobias.madl@medunigraz.at.; BioTechMed-Graz, 8010 Graz, Austria.
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Apr 14; Vol. 117 (15), pp. 8503-8514. Date of Electronic Publication: 2020 Mar 31.
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7
Akademický článek
Aβ oligomers trigger and accelerate Aβ seeding.
Autor: Katzmarski N; Department of Neurology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Ziegler-Waldkirch S; Department of Neurology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Scheffler N; Department of Neurology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Witt C; Department of Neurology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Abou-Ajram C; Biomedical Center (BMC), Ludwig-Maximilians-University Munich, Munich, Germany., Nuscher B; Biomedical Center (BMC), Ludwig-Maximilians-University Munich, Munich, Germany., Prinz M; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Insitute of Neuropathology, Medical Center - University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Haass C; Biomedical Center (BMC), Ludwig-Maximilians-University Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Meyer-Luehmann M; Department of Neurology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Publikováno v: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2020 Jan; Vol. 30 (1), pp. 36-45. Date of Electronic Publication: 2019 Jun 05.
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8
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
Autor: Dorothee Dormann, Madl T, Cf, Valori, Bentmann E, Tahirovic S, Abou-Ajram C, Kremmer E, Ansorge O, Ir, Mackenzie, Neumann M, Haass C
Publikováno v: Europe PubMed Central
The EMBO journal 31(22), 4258-4275 (2012). doi:10.1038/emboj.2012.261
EMBO J. 31, 4258-4275 (2012)
EMBO Journal
Fused in sarcoma (FUS) is a nuclear protein that carries a proline tyrosine nuclear localization signal (PY NLS) and is imported into the nucleus via Transportin (TRN). Defects in nuclear import of FUS have been implicated in neurodegeneration since
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1822b3928235c25835c7e8b5c10b17a1
https://europepmc.org/articles/PMC3501225/
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9
Akademický článek
Pathological Involvement of Protein Phase Separation and Aggregation in Neurodegenerative Diseases.
Autor: Wu, Yinuo1 (AUTHOR) yinuowu@nefu.edu.cn, Ma, Biao2 (AUTHOR) 2022112834bma@nefu.edu.cn, Liu, Chang2 (AUTHOR) lc1677315800@nefu.edu.cn, Li, Dangdang2 (AUTHOR) lidd@nefu.edu.cn, Sui, Guangchao2 (AUTHOR) lidd@nefu.edu.cn
Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p10187. 34p.
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10
Akademický článek
Interaction modulation through arrays of clustered methyl-arginine protein modifications.
Autor: Woodsmith J; Institute of Pharmaceutical Sciences and BioTechMed-Graz, University of Graz, Graz, Austria.; Max Planck Institute for Molecular Genetics, Berlin, Germany., Casado-Medrano V; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Benlasfer N; Max Planck Institute for Molecular Genetics, Berlin, Germany., Eccles RL; Department of Experimental Medicine I, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany., Hutten S; BioMedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany., Heine CL; Institute of Pharmaceutical Sciences and BioTechMed-Graz, University of Graz, Graz, Austria., Thormann V; Max Planck Institute for Molecular Genetics, Berlin, Germany., Abou-Ajram C; BioMedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany., Rocks O; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany., Dormann D; BioMedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Stelzl U; Institute of Pharmaceutical Sciences and BioTechMed-Graz, University of Graz, Graz, Austria.; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Publikováno v: Life science alliance [Life Sci Alliance] 2018 Sep 21; Vol. 1 (5), pp. e201800178. Date of Electronic Publication: 2018 Sep 21 (Print Publication: 2018).
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