A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects

Autor: Liu C, Lu H, Yuan F, Chen WL, Xu HR, Li H, Hsu CP, Egbuna O, Wu J, Dias C, Abosaleem B, Rana J, Monsalvo ML, Li XN, Yu Z

Publikováno v: Clinical Pharmacology: Advances and Applications, Vol Volume 11, Pp 145-153 (2019)

Chao Liu,1 Hong Lu,2 Fei Yuan,1 Wei-Li Chen,1 Hong-Rong Xu,1 Hui Li,1 Cheng-Pang Hsu,3 Ogo Egbuna,3 Jihua Wu,2 Clapton Dias,3 Bassam Abosaleem,3 Jitesh Rana,3 Maria Laura Monsalvo,3 Xue-Ning Li,1 Zhigang Yu4 1Department of Clinical Pharmacology, Zhon

Externí odkaz: https://doaj.org/article/331de057614a45afb696e32413c77748

Performance of the pegfilgrastim on-body injector as studied with placebo buffer in healthy volunteers.

Autor: Joshi RS; a Medical Sciences, Amgen Inc. , Thousand Oaks , CA , USA., Egbuna OI; a Medical Sciences, Amgen Inc. , Thousand Oaks , CA , USA., Cairns AS; b Global Operations, Amgen Inc. , Thousand Oaks , CA , USA., Friedman MJ; c Device Technologies, Amgen Inc. , Thousand Oaks , CA , USA., Abosaleem B; a Medical Sciences, Amgen Inc. , Thousand Oaks , CA , USA., Reiner MT; d Global Biostatistical Science, Amgen Inc. , Thousand Oaks , CA , USA., Morrow PK; e Global Development, Amgen Inc. , Thousand Oaks , CA , USA.

Publikováno v: Current medical research and opinion [Curr Med Res Opin] 2017 Feb; Vol. 33 (2), pp. 379-384. Date of Electronic Publication: 2016 Dec 02.

Tolerability of High-Volume Subcutaneous Injections of a Viscous Placebo Buffer: A Randomized, Crossover Study in Healthy Subjects.

Autor: Dias C; Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, California, 91320, USA. claptondias@gmail.com., Abosaleem B; Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, California, 91320, USA., Crispino C; Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, California, 91320, USA., Gao B; Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, California, 91320, USA.; Currently at BioMarin Pharmaceutical, Inc., San Rafael, California, USA., Shaywitz A; Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, California, 91320, USA.; Currently at Gilead Sciences, Foster City, California, USA.

Publikováno v: AAPS PharmSciTech [AAPS PharmSciTech] 2015 Oct; Vol. 16 (5), pp. 1101-7. Date of Electronic Publication: 2015 Feb 19.

Investigation into the Acceptability of Moderate-to-Large Volume Subcutaneous Injections in Healthy Volunteers: Results from a Single-Center Randomized Controlled Study.

Autor: Akinseye, Chika, Fiorini, Andrew, Jarvis, Emily Louise, Fry, Michelle, Raza, Abid, Soleman, Sara, Igwe, Stephanie, Palmer, Mark

Publikováno v: Medical Devices: Evidence & Research; Oct2024, Vol. 17, p369-384, 16p

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