Identification of potential antiviral compounds from Egyptian sea stars against MERS-CoV with the in vitro and in silico experiments.

Autor: Okasha NI; College of Biotechnology, Misr University for Science and Technology (MUST), 6th of October, Egypt., Abdel-Rahman MA; Zoology Department, Faculty of Science, Suez Canal University, Ismailia, Egypt., Nafie MS; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt., Abo Shama NM; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt., Mahmoud SH; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt., El-Ebeedy DA; College of Biotechnology, Misr University for Science and Technology (MUST), 6th of October, Egypt., Abdel Azeiz AZ; College of Biotechnology, Misr University for Science and Technology (MUST), 6th of October, Egypt.

Publikováno v: Natural product research [Nat Prod Res] 2024 Apr 02, pp. 1-7. Date of Electronic Publication: 2024 Apr 02.

Immunogenicity and Cross-Protective Efficacy Induced by an Inactivated Recombinant Avian Influenza A/H5N1 (Clade 2.3.4.4b) Vaccine against Co-Circulating Influenza A/H5Nx Viruses.

Autor: Mahmoud SH; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., Khalil AA; Veterinary Serum and Vaccine Research Institute, Agricultural Research Center (ARC), Abbasia, Cairo 11381, Egypt., Abo Shama NM; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., El Sayed MF; Central Laboratory for Evaluation of Veterinary Biologics, Agricultural Research Center (ARC), Abbasia, Cairo 11517, Egypt., Soliman RA; Central Laboratory for Evaluation of Veterinary Biologics, Agricultural Research Center (ARC), Abbasia, Cairo 11517, Egypt., Hagag NM; Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center, Giza 12618, Egypt., Yehia N; Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center, Giza 12618, Egypt., Naguib MM; Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center, Giza 12618, Egypt.; Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 75121 Uppsala, Sweden., Arafa AS; Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center, Giza 12618, Egypt., Ali MA; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., El-Safty MM; Central Laboratory for Evaluation of Veterinary Biologics, Agricultural Research Center (ARC), Abbasia, Cairo 11517, Egypt., Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.; Texas Biomedical Research Institute, San Antonio, TX 78227, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2023 Aug 22; Vol. 11 (9). Date of Electronic Publication: 2023 Aug 22.

Ligand-based design, synthesis, computational insights, and in vitro studies of novel N -(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease.

Autor: Elagawany M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt., Elmaaty AA; Department of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt., Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Cairo, Egypt.; Institute of Medical Microbiology, German Center for Infection Research (DZIF), Justus-Liebig University Giessen, Giessen, Germany., Abo Shama NM; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Cairo, Egypt., Santali EY; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, Saudi Arabia., Elgendy B; Center for Clinical Pharmacology, Washington University School of Medicine, University of Health Sciences, St. Louis, MO, USA.; Chemistry Department, Faculty of Science, Benha University, Benha, Egypt., Al-Karmalawy AA; Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2112-2132.

Robust Antiviral Activity of Santonica Flower Extract ( Artemisia cina ) against Avian and Human Influenza A Viruses: In Vitro and Chemoinformatic Studies.

Autor: Hegazy A; Department of Agricultural Microbiology, Faculty of Agriculture, Cairo University, Giza District, 12613Giza, Egypt., Mostafa I; Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig44519, Egypt., Elshaier YAMM; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufia32897, Egypt., Mahmoud SH; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza12622, Egypt., Abo Shama NM; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza12622, Egypt., Shehata M; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza12622, Egypt., Yahya G; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig44519, Egypt., Nasr NF; Department of Agricultural Microbiology, Faculty of Agriculture, Cairo University, Giza District, 12613Giza, Egypt., El-Halawany AM; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Giza11562, Egypt., Ali MA; Department of Agricultural Microbiology, Faculty of Agriculture, Cairo University, Giza District, 12613Giza, Egypt., Ali MA; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza12622, Egypt., Mraheil MA; German Center for Infection Research (DZIF), Institute of Medical Microbiology, Justus-Liebig University, 35392Giessen, Germany., El-Shazly AM; Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig44519, Egypt.; Faculty of Pharmacy, El Saleheya El Gadida University, El Saleheya El Gadida44813, Egypt., Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza12622, Egypt.

Publikováno v: ACS omega [ACS Omega] 2022 Nov 02; Vol. 7 (45), pp. 41212-41223. Date of Electronic Publication: 2022 Nov 02 (Print Publication: 2022).

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies.

Autor: Kutkat O; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., Moatasim Y; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., Al-Karmalawy AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt., Abulkhair HS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, 11884, Egypt., Gomaa MR; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., El-Taweel AN; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., Abo Shama NM; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., GabAllah M; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., Mahmoud DB; Pharmaceutics Department, Egyptian Drug Authority, formerly known as National Organization for Drug Control and Research, Giza, 12654, Egypt., Kayali G; Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas, Houston, TX, 77030, USA.; Human Link DMCC, Dubai, UAE., Ali MA; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt., Kandeil A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt. kandeil_a@hotmail.com., Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt. ahmed_elsayed@daad-alumni.de.

Publikováno v: Scientific reports [Sci Rep] 2022 Jul 28; Vol. 12 (1), pp. 12920. Date of Electronic Publication: 2022 Jul 28.