Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Abnormal platelet aggregation"'
Publikováno v:
IP Journal of Diagnostic Pathology and Oncology. 5:339-343
Thrombotic microangiopathy (TMA) is characterized by microvascular thrombosis due to endothelial injury or abnormal platelet aggregation. It commonly manifests as microangiopathic hemolytic anaemia, thrombocytopenia and organ injury that may include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1429fe5db05ffb74fc3a024ecdeab22
https://doi.org/10.18231/j.jdpo.2020.066
https://doi.org/10.18231/j.jdpo.2020.066
Autor:
Yi-Fan Fang, Jia-Li Jiang, Bing-Chen Zhang, Meng-Die Yin, Fang Yang, Bang-Yue Luo, Jingwei Shao, Ruirui Zhao
Publikováno v:
Pharmacological research. 159
Thrombosis initiated by abnormal platelet aggregation is a pivotal pathological event that precedes most cases of cardiovascular diseases (CVD). Recently, growing evidence indicates that platelet could be a potential target for CVD prevention. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6722cd97f6aa84342467c1f9b4926449
https://pubmed.ncbi.nlm.nih.gov/32562816
https://pubmed.ncbi.nlm.nih.gov/32562816
Autor:
Shruthi Mohan, Wolfgang Bergmeier, Kristy Lee, Brian R. Branchford, Minjie Luo, Justyne Ross, Paul F. Bray, Juliana Perez Botero, Kathleen Freson, Michele P. Lambert, Jorge Di Paola
Publikováno v:
Haematologica
Glanzmann thrombasthenia (GT) is an autosomal recessive disorder of platelet aggregation caused by quantitative or qualitative defects in integrins αIIb and β3. These integrins are encoded by the ITGA2B and ITGB3 genes and form platelet glycoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059fb9d88097570fb0a413bca9af4ee2
https://lirias.kuleuven.be/handle/123456789/652006
https://lirias.kuleuven.be/handle/123456789/652006
Autor:
Jeffrey D. Kerby, Brant M. Wagener, Tate R. Nice, Mike K. Chen, Amy L. Duhachek-Stapelman, Sarah C. Christiaans, Vincent E. Mortellaro, Robert T. Russell, Jean-Francois Pittet, Morgan E. Banks, Steven J. Lisco, Charity J. Morgan
Publikováno v:
Shock. 49:44-52
BACKGROUND The release of damage-associated molecular pattern molecules in the extracellular space secondary to injury has been shown to cause systemic activation of the coagulation system and endothelial cell damage. We hypothesized that pediatric t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4647146ea6190b101f895718739d72
https://doi.org/10.1097/shk.0000000000000902
https://doi.org/10.1097/shk.0000000000000902
Autor:
Dearbhla Doherty, Michelle Lavin, Niamh M O'Connell, Mary Byrne, James S. O’Donnell, Kevin M. Ryan, Evelyn Singleton
Publikováno v:
Transfusion and Apheresis Science. 58:58-60
Glanzmann thrombasthenia (GT) is an autosomal recessive bleeding disorder caused by a defect in platelet integrin αIIbβ3. Given the rarity of the condition (1/1,000,000), assessment and diagnosis should be undertaken in a specialist centre. We repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1ad9f1818c4d184078e3fb8290dc69
https://doi.org/10.1016/j.transci.2018.11.008
https://doi.org/10.1016/j.transci.2018.11.008
Publikováno v:
Phytochemistry Letters. 20:45-48
Three new labdane diterpenoids, leojapones A–C ( 1–3 ), along with a new artifactual analogue ( 4 ) and four known terpenoids, were isolated from the EtOAc extract of the aerial parts of Leonurus japonicus Houtt. Their structures were elucidated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f96c1707223b4c76f2786b3396534963
https://doi.org/10.1016/j.phytol.2017.04.002
https://doi.org/10.1016/j.phytol.2017.04.002
Autor:
Sarah H. O'Brien, Bryce A. Kerlin, Kyle A Davis, Gary M. Woods, Joseph Stanek, Elizabeth L. Kudron
Publikováno v:
Journal of Pediatric Hematology/Oncology. 38:525-528
Delta-granule platelet storage pool deficiency (δ-PSPD) is a poorly studied bleeding diathesis resulting from either decreased granule content or decreased average number of platelet δ-granules. Light transmission aggregometry (LTA) is commonly use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9aeab91dd388ed13a9b7e10d19c7df
https://doi.org/10.1097/mph.0000000000000638
https://doi.org/10.1097/mph.0000000000000638
Publikováno v:
Turkish Journal of Hematology, Vol 33, Iss 2, Pp 127-130 (2016)
Turkish Journal of Hematology
Turkish Journal of Hematology
The aim of this study was to investigate the effects of imatinib mesylate on platelet aggregation and adenosine triphosphate (ATP) release in chronic myeloid leukemia patients.Platelet aggregation and ATP release induced by 5.0 mM adenosine diphospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc8ea3d50c88327eb0188b2018239b2
http://www.tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&un=TJH-03789&look4=
http://www.tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&un=TJH-03789&look4=
Autor:
Véronique Latger-Cannard, Huili Cai, Marie Toussaint, Thomas Lecompte, Marie-Elisabeth Briquel, Frédéric Massin, François Mullier, Birgit Frotscher
Publikováno v:
Seminars in Thrombosis and Hemostasis. 42:282-291
Dense granule disorder is one of the most common platelet abnormalities, resulting from dense granule deficiency or secretion defect. This study was aimed to evaluate the clinical usefulness of the flow cytometric combination of mepacrine uptake/rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e073b7ae1a7a96d9b4f60772d877304
https://doi.org/10.1055/s-0035-1564836
https://doi.org/10.1055/s-0035-1564836
Publikováno v:
Canadian Journal of Chemistry. 93:311-316
P2Y12, a member of the G-protein-coupled receptors, is associated with abnormal platelet aggregation, a condition that contributes to thrombus formation. As receptor antagonists are effective solutions for anti-thrombus, the P2Y12 receptor is a popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d377097766fea171509cc323fd1caf29
https://doi.org/10.1139/cjc-2014-0429
https://doi.org/10.1139/cjc-2014-0429