Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Abish Pius"'
Autor:
Ulka Sachdev, Ricardo Ferrari, Xiangdong Cui, Abish Pius, Amrita Sahu, Michael Reynolds, Hong Liao, Ping Sun, Sunita Shinde, Fabrisia Ambrosio, Sruti Shiva, Patricia Loughran, Melanie Scott
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-17 (2020)
Abstract Background We previously showed that the autophagy inhibitor chloroquine (CQ) increases inflammatory cleaved caspase-1 activity in myocytes, and that caspase-1/11 is protective in sterile liver injury. However, the role of caspase-1/11 in th
Externí odkaz:
https://doaj.org/article/80069bd5f95c4298bb6be131ec3912b7
Autor:
Zachary Clemens, Sruthi Sivakumar, Abish Pius, Amrita Sahu, Sunita Shinde, Hikaru Mamiya, Nathaniel Luketich, Jian Cui, Purushottam Dixit, Joerg D Hoeck, Sebastian Kreuz, Michael Franti, Aaron Barchowsky, Fabrisia Ambrosio
Publikováno v:
eLife, Vol 10 (2021)
Aging is accompanied by disrupted information flow, resulting from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders including skeletal muscle wasting, or sarcopenia. To derive a global metric of growin
Externí odkaz:
https://doaj.org/article/709d9a59e7ce49fba7ee50bebd5fa3c3
Autor:
Sivasubramanium V Bhavani, Li Xiong, Abish Pius, Matthew Semler, Edward T Qian, Philip A Verhoef, Chad Robichaux, Craig M Coopersmith, Matthew M Churpek
Publikováno v:
Journal of the American Medical Informatics Association. 30:1158-1166
Objective Severe infection can lead to organ dysfunction and sepsis. Identifying subphenotypes of infected patients is essential for personalized management. It is unknown how different time series clustering algorithms compare in identifying these s
Autor:
Amrita Sahu, Zachary J. Clemens, Sunita N. Shinde, Sruthi Sivakumar, Abish Pius, Ankit Bhatia, Silvia Picciolini, Cristiano Carlomagno, Alice Gualerzi, Marzia Bedoni, Bennett Van Houten, Mita Lovalekar, Nicholas F. Fitz, Iliya Lefterov, Aaron Barchowsky, Radosveta Koldamova, Fabrisia Ambrosio
Publikováno v:
Nat Aging
Heterochronic blood exchange (HBE) has demonstrated that circulating factors restore youthful features to aged tissues. However, the systemic mediators of those rejuvenating effects remain poorly defined. We show here that the beneficial effect of yo
Autor:
Hikaru Mamiya, Abish Pius, Purushottam D. Dixit, Amrita Sahu, Aaron Barchowsky, Sruthi Sivakumar, Michael Franti, Sunita Shinde, Nathaniel Luketich, Joerg D. Hoeck, Jian Cui, Sebastian Kreuz, Zachary Clemens, Fabrisia Ambrosio
Publikováno v:
eLife, Vol 10 (2021)
Aging is accompanied by disrupted information flow, resulting from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders including skeletal muscle wasting, or sarcopenia. To derive a global metric of growin
Autor:
Abish Pius, Purushottam D. Dixit, Aaron Barchowsky, Nathaniel Luketich, Hikaru Mamiya, Michael Franti, Amrita Sahu, Jian Cui, Sruthi Sivakumar, Sebastian Kreuz, Fabrisia Ambrosio, Joerg D. Hoeck, Sunita Shinde, Zachary Clemens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4801657ccc9728577e02080f3facb41d
https://doi.org/10.7554/elife.61138.sa2
https://doi.org/10.7554/elife.61138.sa2
Autor:
Sebastian Kreuz, Aaron Barchowsky, Joerg D. Hoeck, Abish Pius, Jian Cui, Fabrisia Ambrosio, Michael Franti, Zachary Clemens, Amrita Sahu, Sruthi Sivakumar, Sunita Shinde, Hikaru Mamiya, Nathaniel Luketich
Aging is accompanied by a disrupted information flow, which results from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders such as skeletal muscle wasting, or sarcopenia. To estimate the growing “diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255b04487b8a3769696d14a9ac27a8ed
https://doi.org/10.1101/2020.07.22.207043
https://doi.org/10.1101/2020.07.22.207043
Autor:
Ricardo José Ferrari, Hong Liao, Ping Sun, Ulka Sachdev, Sruti Shiva, Xiangdong Cui, Sunita Shinde, Michael Reynolds, Patricia Loughran, Amrita Sahu, Fabrisia Ambrosio, Abish Pius, Melanie J. Scott
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-17 (2020)
Molecular Medicine
Molecular Medicine
Background We previously showed that the autophagy inhibitor chloroquine (CQ) increases inflammatory cleaved caspase-1 activity in myocytes, and that caspase-1/11 is protective in sterile liver injury. However, the role of caspase-1/11 in the recover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94265f916cb6ecf1947a8dc636ae356a
https://doi.org/10.21203/rs.3.rs-25610/v2
https://doi.org/10.21203/rs.3.rs-25610/v2
Autor:
Abish Pius, Joerg D. Hoeck, Amrita Sahu, Amin Cheikhi, Hua Li, Aaron Barchowsky, Zachary Clemens, Fabrisia Ambrosio, Sunita Shinde, Michael Franti, Charles A. Kennedy
Publikováno v:
J Gerontol A Biol Sci Med Sci
The year 2017 marked the 20th anniversary of the first publication describing Klotho. This single protein was and is remarkable in that its absence in mice conferred an accelerated aging, or progeroid, phenotype with a dramatically shortened life spa