Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Abir Lefsay"'
Autor:
Niluni M. Wijesundara, Song F. Lee, David N. Langelaan, Abir Lefsay, H.P. Vasantha Rupasinghe
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 3, Pp 100614- (2024)
Background: Phospholipids are significant constituents of bacterial membranes. Bacteria can alter their cytoplasmic membrane fatty acid composition in response to changing environmental stress conditions. Carvacrol, a mono-terpenoid phenol, has excel
Externí odkaz:
https://doaj.org/article/631843ebb3234a759a7c45c4687a7d65
Autor:
Mahtab Tavasoli, Sarah Lahire, Stanislav Sokolenko, Robyn Novorolsky, Sarah Anne Reid, Abir Lefsay, Meredith O. C. Otley, Kitipong Uaesoontrachoon, Joyce Rowsell, Sadish Srinivassane, Molly Praest, Alexandra MacKinnon, Melissa Stella Mammoliti, Ashley Alyssa Maloney, Marina Moraca, J. Pedro Fernandez-Murray, Meagan McKenna, Christopher J. Sinal, Kanneboyina Nagaraju, George S. Robertson, Eric P. Hoffman, Christopher R. McMaster
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Mutations in the CHKB gene cause muscular dystrophy. Here, the authors show that in mouse models of the disease changes in lipid metabolism are associated with decreased PPAR signaling, and show PPAR agonists can rescue expression of injury markers i
Externí odkaz:
https://doaj.org/article/8397e994802c4cd4af32c80fc27420fc
Autor:
Mahtab Tavasoli, Tiam Feridooni, Hirad Feridooni, Stanislav Sokolenko, Abhishek Mishra, Abir Lefsay, Sadish Srinivassane, Sarah Anne Reid, Joyce Rowsell, Molly Praest, Alexandra MacKinnon, Melissa Mammoliti, Ashley Alyssa Maloney, Marina Moraca, Kitipong Uaesoontrachoon, Kanneboyina Nagaraju, Eric P. Hoffman, Kishore B.S. Pasumarthi, Christopher R. McMaster
Publikováno v:
The Journal of biological chemistry. 298(3)
The CHKB gene encodes choline kinase β, which catalyzes the first step in the biosynthetic pathway for the major phospholipid phosphatidylcholine. Homozygous loss-of-function variants in human CHKB are associated with a congenital muscular dystrophy
Autor:
Joyce Rowsell, Mahtab Tavasoli, Abir Lefsay, Melissa Mammoliti, Molly Praest, J. Pedro Fernández-Murray, Kitipong Uaesoontrachoon, Kanneboyina Nagaraju, Sadish Srinivassane, Sarah Lahire, Ashley Maloney, Eric P. Hoffman, Stanislav Sokolenko, Christopher R. McMaster, Marina Moraca, Alexandra MacKinnon
CHKB encodes one of two mammalian choline kinase enzymes that catalyze the first step in the synthesis of the major membrane phospholipid, phosphatidylcholine (PC). In humans, inactivation of the CHKB gene causes a recessive form of a rostral-to-caud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ed1973477bc63e7aebf2789c8a358cb
https://doi.org/10.21203/rs.3.rs-64129/v1
https://doi.org/10.21203/rs.3.rs-64129/v1
Autor:
Mahtab Tavasoli, Sarah Lahire, Stanislav Sokolenko, Robyn Novorolsky, Sarah Anne Reid, Abir Lefsay, Meredith O. C. Otley, Kitipong Uaesoontrachoon, Joyce Rowsell, Sadish Srinivassane, Molly Praest, Alexandra MacKinnon, Melissa Stella Mammoliti, Ashley Alyssa Maloney, Marina Moraca, J. Pedro Fernandez-Murray, Meagan McKenna, Christopher J. Sinal, Kanneboyina Nagaraju, George S. Robertson, Eric P. Hoffman, Christopher R. McMaster
Publikováno v:
Nature communications. 13(1)
CHKB encodes one of two mammalian choline kinase enzymes that catalyze the first step in the synthesis of the membrane phospholipid phosphatidylcholine. In humans and mice, inactivation of the CHKB gene (Chkb in mice) causes a recessive rostral-to-ca