Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Abiodun Elegbede"'
Publikováno v:
In Life Sciences 2002 71(4):421-436
Publikováno v:
Life Sciences. 73:2831-2840
The role of the monoterpenes, especially limonene and perillyl alcohol, in the treatment of certain cancers is currently being evaluated in clinical trials. In this study, the effects of perillyl alcohol (POH) and its analog, perillaldehyde (PALD), o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad63dfdd7bc88af0cfb121afb3d0d10b
https://doi.org/10.1016/s0024-3205(03)00701-x
https://doi.org/10.1016/s0024-3205(03)00701-x
Autor:
Pamela L. Crowell, Michael N. Gould, Charles E. Elson, Jill D. Haag, Abiodun Elegbede, Howard H. Bailey
Publikováno v:
Cancer Chemotherapy and Pharmacology. 35:31-37
d-Limonene has efficacy in preclinical models of breast cancer, causing > 80% of carcinomas to regress with little host toxicity. We performed a pilot study on healthy human volunteers to identify plasma metabolites of limonene and to assess the toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e33c7e5b21f7a01d1faa60434e0dacb
https://doi.org/10.1007/bf00686281
https://doi.org/10.1007/bf00686281
Breast cancer is the second leading cause of cancer deaths among women in the United States. Several treatment options exist, with different side effects. To alleviate the side effects, several research groups have studied chemotherapeutic effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8e39fc9b754e37fb3abba7e6d05fb7
https://europepmc.org/articles/PMC2907645/
https://europepmc.org/articles/PMC2907645/
Publikováno v:
Cancer investigation. 26(9)
Advanced prostate cancer cells are typically hormone independent, resistant to apoptosis and do not respond to chemotherapeutic agents. The ability of methyl jasmonate (MJ) and cis-jasmone (CJ) to inhibit growth in hormone independent prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164aa57718c3cc5f0a1fd031478887c6
https://pubmed.ncbi.nlm.nih.gov/18798057
https://pubmed.ncbi.nlm.nih.gov/18798057
Publikováno v:
Anti-cancer drugs. 19(8)
In recent years, studies with plant compounds have shown both chemotherapeutic and chemopreventive properties. This study with plant stress hormones (jasmonates) showed growth inhibitory effects in breast cancer cells. cis-Jasmone and methyl jasmonat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cb178a22227e734290073a05269c65
https://pubmed.ncbi.nlm.nih.gov/18690087
https://pubmed.ncbi.nlm.nih.gov/18690087
Publikováno v:
Journal of experimental therapeuticsoncology. 6(4)
Methyl jasmonate--a plant stress hormone with striking resemblance to lipoxygenase products have been reported to induce apoptosis in several cancers. However, 5-HETE--a product of the lipoxygenase pathway has been implicated in human prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73784c0c82596c9b38438b7079f76290
https://pubmed.ncbi.nlm.nih.gov/18038760
https://pubmed.ncbi.nlm.nih.gov/18038760
Publikováno v:
Cancer letters. 257(2)
Plant products such as perillyl alcohol have been reported to possess anti-tumor activities against a number of human cancers though the mechanism of action has not yet been elucidated. The effects of perillyl alcohol (POH) and its metabolite perilli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6834bddbf920e7f6e822b73ea95d3663
https://pubmed.ncbi.nlm.nih.gov/17888568
https://pubmed.ncbi.nlm.nih.gov/17888568
Autor:
Laxmi Yeruva, Keon J. Pierre, J. Abiodun Elegbede, Robert C. Wang, Stephen W. Carper, Beau J. Toy
Publikováno v:
Experimental lung research. 32(10)
The jasmonates, cis-jasmone (CJ) and methyl jasmonate (MJ), were investigated for their effects against NSCLC cell lines A549 and H520. CJ or MJ inhibited the proliferation of both cell lines in a dose-dependent manner as well as induced cell cycle a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47b6abf1fe4b4931044bccf201d845a
https://pubmed.ncbi.nlm.nih.gov/17169856
https://pubmed.ncbi.nlm.nih.gov/17169856
Publikováno v:
Anticancer research. 24(5A)
Perillyl alcohol (POH) elicited anticarcinogenic effects in a number of cancer models and pharmacokinetic studies in humans revealed that PA is the major circulating metabolite following POH administration.Effects of PA or POH alone, or in combinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d66d4fdebfaf4d36cd182971d85c6bf0
https://pubmed.ncbi.nlm.nih.gov/15517920
https://pubmed.ncbi.nlm.nih.gov/15517920