Formulation and evaluation of detarium oil based organogel for sustained release of metronidazole via topical delivery

Autor: Gbemisola W. Akande, Abimbola Sowemimo, Margaret O. Ilomuanya, Pal Kunal, Uloma Ubani-Ukoma

Publikováno v: Journal of Pharmacy & Bioresources. 17:96-104

The rationale for this study was to increase the absorption of model drug metronidazole by formulating an organogel using detarium oil in place of conventional oils used in drug formulation such as liquid paraffin. The organogels were prepared by flu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bec1d736317dec3ce4a3228f547ecc6
https://doi.org/10.4314/jpb.v17i2.3

Toxicological evaluation of the stem bark of Burkea africana hook. (Caesalpiniaceae) in wistar rats

Autor: O.K. Eboji, Fatimah B. Abdulkareem, KB Badmos, Margaret O. Sofidiya, O.O. Ogunkunle, Abimbola Sowemimo

Publikováno v: Nigerian Journal of Natural Products and Medicine. 23:33-40

Burkea africana Hook. (Caesalpiniaceae) is used traditionally to treat ulcers, headaches, skin disease and tumors. The study investigated the acute, sub-acute and chronic toxicity profiles of the ethanolic extract of Burkea africana stem bark. Rats o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f990d3250ff620d92f3cb5959ac8c6bd
https://doi.org/10.4314/njnpm.v23i1.5

COVID-19 Pandemic: A Case for Phytomedicines

Autor: O.B. Salu, O. E. Ade-Ademilua, Ifeoma C. Orabueze, Ismail O. Ishola, Ibrahim A. Oreagba, Abidemi J. Akindele, Olayinka T. Asekun, Olufunsho Awodele, Abimbola Sowemimo, Foluso O. Agunbiade, Olukemi A. Odukoya, Margaret O. Sofidiya, Acedhars Unilag Covid Response Team, M.O. Akinleye

Publikováno v: Natural Product Communications

Coronavirus disease 2019 (COVID-19) is an infection caused by a newly discovered coronavirus which was identified in Wuhan, China. The race is on globally to repurpose drugs for COVID-19 and develop a safe and effective vaccine against the disease. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4924468dc305628fcc0e1226fd52c
http://europepmc.org/articles/PMC7429914

Development and characterization of collagen-based electrospun scaffolds containing silver sulphadiazine and Aspalathus linearis extract for potential wound healing applications

Autor: Boladale O. Silva, Dalene de Beer, Adannaya C. Adebona, Samson Oluropo Adeosun, Margaret O. Ilomuanya, Weiguang Wang, Abimbola Sowemimo, Chioma L. Eziegbo, Elizabeth Joubert

Publikováno v: Wang, W 2020, ' Development and characterization of collagen‑based electrospun scaffolds containing silver sulphadiazine and Aspalathus linearis extract for potential wound healing applications ', SN Applied Sciences . https://doi.org/10.1007/s42452-020-2701-8

Bone, skin and soft tissue chronic wounds emanating from burns or bacterial infections which persist due to prolonged tissue inflammation contribute to a delay in wound healing. Electrospun biomimetic scaffolds produced from biodegradable polymers ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520d3526ee5946adfff78a5a77ac6bea
https://doi.org/10.1007/s42452-020-2701-8

Burkea africana Hook (Caesalpiniaceae) ethanolic extract causes cell cycle arrest at M phase and induces caspase dependent apoptosis

Autor: Luanne Venables, M. van de Venter, O.K. Eboji, Margaret O. Sofidiya, Trevor Koekemoer, Abimbola Sowemimo

Publikováno v: South African Journal of Botany. 112:361-367

Burkea africana Hook (Caesalpiniaceae) is a small to medium deciduous flat-topped tree up to 20 m tall that grows in Western and Southern Africa. Traditionally the bark decoction is used in treatment of fever, inflammation and cancer. Cytotoxic activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2547d2d3ade6b51d4772b90fa6d2e044
https://doi.org/10.1016/j.sajb.2017.06.013