Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Abimael González‐Hernández"'
Autor:
Gustavo López-Córdoba, Guadalupe Martínez-Lorenzana, Jair Lozano-Cuenca, Miguel Condés-Lara, Abimael González-Hernández
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Spinal α2-adrenoceptor induces analgesia by neuronal inhibition of primary afferent fibers. This family receptor coupled to Gi/o proteins can be subdivided into three functional subtypes: α2A, α2B, and α2C-adrenoceptors, and current evidence on s
Externí odkaz:
https://doaj.org/article/22ce4c54b3c542b694794850da7e7d80
Autor:
Abimael González-Hernández, Bruno A. Marichal-Cancino, Antoinette MaassenVanDenBrink, Carlos M. Villalón
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1864 (2023)
5-Hydroxytryptamine (5-HT), or serotonin, plays a crucial role as a neuromodulator and/or neurotransmitter of several nervous system functions. Its actions are complex, and depend on multiple factors, including the type of effector or receptor activa
Externí odkaz:
https://doaj.org/article/e451a25871da4b58ba7bd927797d62ac
Autor:
Antonio Espinosa De Los Monteros-Zúñiga, Guadalupe Martínez-Lorenzana, Miguel Condés-Lara, Abimael González-Hernández
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The first few days post-surgery, patients experience intense pain, hypersensitivity and consequently tend to have minor locomotor activity to avoid pain. Certainly, injury to peripheral tissues produces pain and increases sensitivity to painful (hype
Externí odkaz:
https://doaj.org/article/c95353602eb64e44a3d9293fd9bea62e
Autor:
Abimael González-Hernández, Jair Lozano-Cuenca, Bruno A. Marichal-Cancino, Antoinette MaassenVanDenBrink, Carlos M. Villalón
Publikováno v:
The Journal of Headache and Pain, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Dihydroergotamine (DHE) is an antimigraine drug that produces cranial vasoconstriction and inhibits trigeminal CGRP release; furthermore, it inhibits the vasodepressor sensory CGRPergic outflow, but the receptors involved remain u
Externí odkaz:
https://doaj.org/article/3e3b59bbd6584a2696e41e8f0149ebd8
Autor:
Raquel Guerrero-Alba, Paulino Barragán-Iglesias, Abimael González-Hernández, Eduardo E. Valdez-Moráles, Vinicio Granados-Soto, Miguel Condés-Lara, Martín G. Rodríguez, Bruno A. Marichal-Cancino
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
Background: Marijuana extracts (cannabinoids) have been used for several millennia for pain treatment. Regarding the site of action, cannabinoids are highly promiscuous molecules, but only two cannabinoid receptors (CB1 and CB2) have been deeply stud
Externí odkaz:
https://doaj.org/article/1994637223cd48c49de0d91a3341c1da
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. :1-13
Migraine is a prevalent medical condition and the second most disabling neurological disorder. Regarding its pathophysiology, calcitonin gene-related peptide (CGRP) plays a key role, and, consequently, specific antimigraine pharmacotherapy has been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cfd4cd215c99ba8658e5494fbfb161
https://doi.org/10.1080/17425255.2021.1982892
https://doi.org/10.1080/17425255.2021.1982892
Autor:
Guadalupe Martínez-Lorenzana, Miguel Condés-Lara, Antonio Espinosa de los Monteros-Zúñiga, Abimael González-Hernández
Publikováno v:
ACS Chemical Neuroscience. 12:3140-3147
Behavioral and electrophysiological data show that at the spinal level, oxytocin inhibits pain transmission by activation of oxytocin receptors (OTRs). Canonically, OTRs are coupled to Gq proteins, which induce a rise of intracellular Ca2+ by activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a55bf6f6b3ac9b64928ee8f585a29e
https://doi.org/10.1021/acschemneuro.1c00471
https://doi.org/10.1021/acschemneuro.1c00471
Autor:
Gustavo, López-Córdoba, Guadalupe, Martínez-Lorenzana, Jair, Lozano-Cuenca, Miguel, Condés-Lara, Abimael, González-Hernández
Publikováno v:
Frontiers in pharmacology. 13
Spinal α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bab012ab5b59844f8e72863fb20a941
https://pubmed.ncbi.nlm.nih.gov/36506544
https://pubmed.ncbi.nlm.nih.gov/36506544
Autor:
Abimael González-Hernández, Guadalupe Martínez-Lorenzana, Mohammed Gamal-Eltrabily, Miguel Condés-Lara
Publikováno v:
Neuroscience. 458:256-270
Nociception is the neuronal process of encoding noxious stimuli and could be modulated at peripheral, spinal, brainstem, and cortical levels. At cortical levels, several areas including the anterior cingulate cortex (ACC), prefrontal cortex (PFC), ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a53f884b9c5b2cf890599b3ab0a02ea
https://doi.org/10.1016/j.neuroscience.2021.01.001
https://doi.org/10.1016/j.neuroscience.2021.01.001
Autor:
Ana B. Salinas-Abarca, Guadalupe Martínez-Lorenzana, Miguel Condés-Lara, Abimael González-Hernández
Publikováno v:
Experimental Neurology. 363:114383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df569b19df0602a55a7a84d9b443f873
https://doi.org/10.1016/j.expneurol.2023.114383
https://doi.org/10.1016/j.expneurol.2023.114383