Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Abigale Lade"'
Autor:
Veronica Calvo, Julio A. Aguirre-Ghiso, Youngmin A. Lee, Daisuke Hasegawa, Scott L. Friedman, Hsin I. Chou, Alvaro Avivar-Valderas, Eduardo F. Farias, Abigale Lade
Publikováno v:
Molecular and Cellular Biology. 35:1543-1556
Xbp1, a key mediator of the unfolded protein response (UPR), is activated by IRE1α-mediated splicing, which results in a frameshift to encode a protein with transcriptional activity. However, the direct function of Xbp1 in epithelial cells during ma
Autor:
Abigale Lade, Arthur I. Cederbaum, Benjamin Wooden, Natalia Nieto, Yujin Hoshida, Ana Blas-Garcia, Joel T. Dudley, Daniel F. Hicks, Michael C. Wallace, Scott L. Friedman, Benjamin Redhead, Nicolas Goossens, Takuma Tsuchida, Bryan C. Fuchs, Youngmin A. Lee
Publikováno v:
Scientific Reports
We have used a computational approach to identify anti-fibrotic therapies by querying a transcriptome. A transcriptome signature of activated hepatic stellate cells (HSCs), the primary collagen-secreting cell in liver, and queried against a transcrip
Publikováno v:
Current Opinion in Oncology. 26:100-107
We review accumulating evidence that nonalcoholic steatohepatitis (NASH), a more advanced form of nonalcoholic fatty liver disease (NAFLD), predisposes patients to the risk of developing hepatocellular carcinoma (HCC), and we summarize recent advance
Publikováno v:
Journal of Biological Chemistry. 287:22789-22798
Hepatic competence, specification, and liver bud expansion during development depend on precise temporal modulation of the Wnt/β-catenin signaling. Also, loss- and gain-of-function studies have revealed pleiotropic roles of β-catenin in proliferati
Autor:
Abigale Lade, Satdarshan P.S. Monga
Publikováno v:
Developmental Dynamics. 240:486-500
The Wnt/β-catenin pathway is an evolutionarily conserved signaling cascade that plays key roles in development and adult tissue homeostasis and is aberrantly activated in many tumors. Over a decade of work in mouse, chick, xenopus, and zebrafish mod
Autor:
Xiaochen Sun, Swan N. Thung, Youngmin A. Lee, Scott L. Friedman, Philippe Soriano, Peri Kocabayoglu, Ana Cristina Dragomir, Abigale Lade, Yujin Hoshida, Maria Isabel Fiel, Costica Aloman
Publikováno v:
Journal of hepatology
Background & Aims Rapid induction of β-PDGF receptor (β-PDGFR) is a core feature of hepatic stellate cell activation, but its cellular impact in vivo is not well characterized. We explored the contribution of β-PDGFR-mediated pathway activation to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a8bdf45acc48a566a4523b9896a519
http://europepmc.org/articles/pmc4475471
http://europepmc.org/articles/pmc4475471
Autor:
Abigale Lade, Satdarshan P.S. Monga
Publikováno v:
The FASEB Journal. 25
A truncated beta‐catenin species promotes hepatocyte differentiation in late fetal liver development
Autor:
Satdarshan P.S. Monga, Abigale Lade
Publikováno v:
The FASEB Journal. 25
Autor:
Abigale Lade, Satdarshan P.S. Monga
Publikováno v:
The FASEB Journal. 24
Autor:
Lade A; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA *Abigale Lade and Luke A. Noon contributed equally to the writing of this work., Noon LA, Friedman SL
Publikováno v:
Current opinion in oncology [Curr Opin Oncol] 2014 Jan; Vol. 26 (1), pp. 100-7.