Výsledky vyhledávání - "Abigail T. Grapes"

Supplementary Table S1 from Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors

Autor: William G. Cance, Abigail T. Grapes, Sheila A. Figel, Felicia L. Lenzo, Timothy A. Marlowe

Statistics for Figure 1 Excel File

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f3454c5b5facd8834d31c373f60a14
https://doi.org/10.1158/1535-7163.22508238.v1

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Supplementary Materials and Supplementary Figures S1-S15 from Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors

Autor: William G. Cance, Abigail T. Grapes, Sheila A. Figel, Felicia L. Lenzo, Timothy A. Marlowe

PathScan® RTK Signaling Antibody Array Kit Target Map (Cell Signaling) Antibodies and Other Reagents Fig. S1. Quantification of MDA-MB-453 and SkBr3 immunoblot experiments from Fig. 1; Fig. S2. Quantification of H292 and A549 immunoblot experiments

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8a94447e89dea51701ea1d7cea4c06
https://doi.org/10.1158/1535-7163.22508244.v1

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Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors

Autor: Sheila Figel, Abigail T. Grapes, William G. Cance, Felicia L. Lenzo, Timothy Marlowe

Publikováno v: Molecular cancer therapeutics. 15(12)

Focal adhesion kinase (FAK) is a major drug target in cancer and current inhibitors targeted to the ATP-binding pocket of the kinase domain have entered clinical trials. However, preliminary results have shown limited single-agent efficacy in patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a72f59bb50622e2a579cf5e4dfca679
https://pubmed.ncbi.nlm.nih.gov/27638858

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