Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Abigail S. Hackam"'
Autor:
Gabrielle A. Albano, Abigail S. Hackam
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
In this review, we explore the connections between developmental embryology and axonal regeneration. Genes that regulate embryogenesis and central nervous system (CNS) development are discussed for their therapeutic potential to induce axonal and cel
Externí odkaz:
https://doaj.org/article/7f567355f7154eae9e7880196ff7ec9d
Autor:
Karin Rose Lypka, Tal Carmy-Bennun, Kimberly N. Garces, Alexander W. Venanzi, Abigail S. Hackam
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Optic nerve trauma caused by crush injury is frequently used for investigating experimental treatments that protect retinal ganglion cells (RGCs) and induce axonal regrowth. Retaining outer retinal light responses is essential for
Externí odkaz:
https://doaj.org/article/cceb1fb5118541b1beb0d837179c1808
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Retinal degenerative diseases are a group of conditions characterized by photoreceptor death and vision loss. Excessive inflammation and microglial activation contribute to the pathology of retinal degenerations and a major focus
Externí odkaz:
https://doaj.org/article/a10163cc9f104537b4ac834508435024
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 10, Pp 2149-2152 (2022)
Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell stress, neuronal disease, and tumors. Recent studies in various tissues indicate that interleukin-27 has complex activating and inhibitory properties in
Externí odkaz:
https://doaj.org/article/8d16be875b084bb4aadc3d48cf1d0a71
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 293 (2023)
Background: Diabetic retinopathy (DR) afflicts more than 93 million people worldwide and is a leading cause of vision loss in working adults. While DR therapies are available, early DR development may go undetected without treatment due to the lack o
Externí odkaz:
https://doaj.org/article/244fedc961b74843a28b9e16586f10b5
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
The ketogenic diet (KD) is a high-fat low-carbohydrate diet that has been used for decades as a non-pharmacologic approach to treat metabolic disorders and refractory pediatric epilepsy. In recent years, enthusiasm for the KD has increased in the sci
Externí odkaz:
https://doaj.org/article/db60a2f3aedb47909154aef3cf4407cc
Autor:
Muhammad Zain Chauhan, Jennifer Arcuri, Kevin K. Park, Maroof Khan Zafar, Rabeet Fatmi, Abigail S. Hackam, Yuqin Yin, Larry Benowitz, Jeffrey L. Goldberg, Mohammad Samarah, Sanjoy K. Bhattacharya
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Growth cones (GCs) are structures associated with growing neurons. GC membrane expansion, which necessitates protein-lipid interactions, is critical to axonal elongation in development and in adult neuritogenesis. We present a multi-omic ana
Externí odkaz:
https://doaj.org/article/49717cf437a34f7f981dfed84049db4b
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 1, Pp 43-52 (2018)
The canonical Wnt/β-catenin pathway is a highly conserved signaling cascade that plays critical roles during embryogenesis. Wnt ligands regulate axonal extension, growth cone guidance and synaptogenesis throughout the developing central nervous syst
Externí odkaz:
https://doaj.org/article/713cc910b1a94741a46ae5917c5b5545
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
We present lipid profiling data from mouse retina and optic nerve after optic nerve crush and during Wnt3a-induced axonal regeneration at 7 and 15 days post-crush. This data is available at the Metabolomics Workbench, http://www.metabolomicsworkbench
Externí odkaz:
https://doaj.org/article/eef7b6c73093453ea993c5a144bdbf2b
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cdac216d1b193b2580d791bf27afe7a
https://doi.org/10.1089/jop.2023.0001
https://doi.org/10.1089/jop.2023.0001