Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Abigail M. Anderson"'
Autor:
Quan Chen, Bin Huang, Abigail M. Anderson, Eric B. Durbin, Susanne M. Arnold, Jill M. Kolesar
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAppalachia is a region with significant cancer disparities in incidence and mortality compared to Kentucky and the United States. However, the contribution of these cancer health disparities to subsequent primary cancers (SPCs) among surviv
Externí odkaz:
https://doaj.org/article/e8b7bb7b7edf48d094de88563a57fbec
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 8, Pp 2427-2438 (2017)
A gain-of-function mutation in the tyrosine kinase JAK2 (JAK2V617F) causes human myeloproliferative neoplasms (MPNs). These patients present with high numbers of myeloid lineage cells and have numerous complications. Since current MPN therapies are n
Externí odkaz:
https://doaj.org/article/3e8b49aadd684781beed978efafe2100
Autor:
Brian T. Burgess, Abigail M. Anderson, J. Robert McCorkle, Jianrong Wu, Frederick R. Ueland, Jill M. Kolesar
Publikováno v:
Diagnostics, Vol 10, Iss 2, p 121 (2020)
Objective: Despite the promise of PARP inhibitors (PARPi) for treating BRCA1/2 mutated ovarian cancer (OC), drug resistance invariably develops. We hypothesized rationale drug combinations, targeting key molecules in DNA repair pathways and the cell
Externí odkaz:
https://doaj.org/article/719bebe97d414206880c0a4241d77a68
Autor:
Brian T, Burgess, Abigail M, Anderson, J Robert, McCorkle, Jianrong, Wu, Frederick R, Ueland, Jill M, Kolesar
Publikováno v:
Diagnostics
Objective: Despite the promise of PARP inhibitors (PARPi) for treating BRCA1/2 mutated ovarian cancer (OC), drug resistance invariably develops. We hypothesized rationale drug combinations, targeting key molecules in DNA repair pathways and the cell
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 8, Pp 2427-2438 (2017)
A gain-of-function mutation in the tyrosine kinase JAK2 (JAK2V617F) causes human myeloproliferative neoplasms (MPNs). These patients present with high numbers of myeloid lineage cells and have numerous complications. Since current MPN therapies are n
Autor:
Marisa A. Strobel, Amy L. Lenz, Abigail M. Anderson, Alissa V. Fial, Karen M. Kruger, Joseph Krzak, Bruce A. MacWilliams
Publikováno v:
Journal of Biomechanics. 120:110344
The introduction of biplane fluoroscopy has created the ability to evaluate in vivo motion, enabling six degree-of-freedom measurement of the tibiotalar and subtalar joints. Although the International Society of Biomechanics defines a standard method
Publikováno v:
Seminars in Cell & Developmental Biology. 28:96-103
Sustained activation of the JAK/STAT pathway is causal to human cancers. This pathway is less complex in Drosophila, and its dysregulation has been linked to several tumor models in this organism. Here, we discuss models of metastatic epithelial and
Autor:
Aloma B. Rodrigues, Abigail M. Anderson, Maria Sol Flaherty, Erika A. Bach, Marc Amoyel, Aidee Ayala-Camargo
Publikováno v:
Developmental Biology. 382(2):413-426
JAK/STAT signaling is localized to the wing hinge, but its function there is not known. Here we show that the Drosophila STAT Stat92E is downstream of Homothorax and is required for hinge development by cell-autonomously regulating hinge-specific fac
Publikováno v:
Developmental biology. 390(2)
Sine Oculis (So), the founding member of the SIX family of homeobox transcription factors, binds to sequence specific DNA elements and regulates transcription of downstream target genes. It does so, in part, through the formation of distinct biochemi
Publikováno v:
Development (Cambridge, England). 139(5)
The SIX family of homeodomain-containing DNA-binding proteins play crucial roles in both Drosophila and vertebrate retinal specification. In flies, three such family members exist, but only two, Sine oculis (So) and Optix, are expressed and function