Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Abigail Lapham"'
Autor:
Matthew Brimmell, Melanie Lee, Abigail Lapham, Jemimah E. Adams, Graham Packham, Alex Paterson
Publikováno v:
Gene. 432:112-117
The antiapoptotic BCL-2 family protein BCL-W is often overexpressed in colorectal carcinoma (CRC) where it correlates with advanced stage and expression of p53. In this work we have analysed the Bcl-w promoter to identify potential regulators of BCL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05879a1054deb2edcc19df24239899f8
https://doi.org/10.1016/j.gene.2008.12.002
https://doi.org/10.1016/j.gene.2008.12.002
Publikováno v:
Apoptosis. 13:972-982
Cobalt promotes apoptosis in multiple cell systems, however, the molecular mechanisms that influence cobalt-induced apoptosis are not fully understood. We investigated mechanisms of cobalt chloride induced apoptosis in HCT116 colorectal cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd57733c7314a66585c2c8776f0bf2a6
https://doi.org/10.1007/s10495-008-0229-2
https://doi.org/10.1007/s10495-008-0229-2
Autor:
C. Howard Barton, Irene Yeung, Abigail Lapham, Michal Alter-Koltunoff, Ben-Zion Levi, Holly Bowen, Derek A. Mann, V. Hugh Perry, E.S. Phillips
Publikováno v:
Journal of Biological Chemistry. 278:36017-36026
Murine Nramp1 encodes a divalent cation transporter that is expressed in late endosomes/lysosomes of macrophages, and the transported cations facilitate intracellular pathogen growth control. The Nramp1 promoter is TATA box-deficient, has two initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70d4060100dac0a5525f6b6292bde6d5
https://doi.org/10.1074/jbc.m304301200
https://doi.org/10.1074/jbc.m304301200
Publikováno v:
Biochemical Society Transactions. 32:1084-1086
Slc11a1/Nramp1 (solute carrier family 11 member a1/murine natural resistance-associated macrophage protein 1 gene) encodes a divalent cation transporter that resides within lysosomes/late endosomes of macrophages. Nramp1 modulates the cellular distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17d1b4a17d76cb7af61084f6b6b25dd
https://doi.org/10.1042/bst0321084
https://doi.org/10.1042/bst0321084
Autor:
Mark A. Hanson, Karen A. Lillycrop, Keith M. Godfrey, Abigail Lapham, Peter D. Gluckman, Graham C. Burdge
In the developed world childhood obesity, diabetes, cardiovascular disease, and non-alcoholic fatty liver disease are all increasing at alarming rates. These non-communicable diseases (NCD) now account for 60% of deaths globally. There is an urgent n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7a1aa424158ab28e63c916c583a2388
https://doi.org/10.1016/b978-0-12-388415-2.00015-9
https://doi.org/10.1016/b978-0-12-388415-2.00015-9
