Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Abigail L. Stevenson"'
Publikováno v:
Biochemical Society Transactions. 38:1587-1592
Eukaryotic translation initiation is an intricate process involving at least 11 formally classified eIFs (eukaryotic initiation factors), which, together with the ribosome, comprise one of the largest molecular machines in the cell. Studying such hug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a67758a9afee70a1e2de8f326fbe1f1
https://doi.org/10.1042/bst0381587
https://doi.org/10.1042/bst0381587
Autor:
Chris J. Norbury, Jürg Bähler, Stephen Watt, Hsiang-Ju Chen, Chun-Yu Wang, Wei-Ling Wen, Stephen E. Kearsey, Shao-Win Wang, Abigail L. Stevenson
Publikováno v:
Nucleic Acids Research
Multiple KH-domain proteins, collectively known as vigilins, are evolutionarily highly conserved proteins that are present in eukaryotic organisms from yeast to metazoa. Proposed roles for vigilins include chromosome segregation, messenger RNA (mRNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620a1b18a4358eb8d84e1c1862c462d0
https://doi.org/10.1093/nar/gkq555
https://doi.org/10.1093/nar/gkq555
Publikováno v:
Molecular and Cellular Biology. 26:4435-4447
Fission yeast Cid12 is a member of the Cid1 family of specialized poly(A) polymerases. Like cells lacking cid1, cid12Delta mutants were shown to have checkpoint defects when DNA replication was inhibited. Here, we show that Cid12 is also required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea76a4c1adf70125a246f9fc659a1ed
https://doi.org/10.1128/mcb.02205-05
https://doi.org/10.1128/mcb.02205-05
Publikováno v:
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 19(4)
Venous thromboembolism (VTE) causes significant morbidity and mortality in hospitalized medical populations; however, medical patients do not currently receive thromboprophylaxis beyond their hospital stay. We reviewed the real-life occurrence of VTE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803eedd135244b8c02c359bb14dbb051
https://pubmed.ncbi.nlm.nih.gov/23610237
https://pubmed.ncbi.nlm.nih.gov/23610237
Schizosaccharomyces pombe Rqh1 is a member of the RecQ DNA helicase family. Members of this protein family are mutated in cancer predisposition diseases, causing Bloom’s, Werner, and Rothmund-Thomson syndromes. Rqh1 forms a complex with topoisomera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aaffcaf0e697204b4e7c8439d72c32a
https://europepmc.org/articles/PMC1820446/
https://europepmc.org/articles/PMC1820446/
Autor:
Abigail L. Stevenson, Chris J. Norbury
Publikováno v:
Yeast (Chichester, England). 23(13)
Polyadenylation is an essential processing step for most eukaryotic mRNAs. In the nucleus, poly(A) polymerase adds poly(A) tails to mRNA 3′ ends, contributing to their export, stability and translatability. Recently, a novel class of non-canonical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2565f2c2720d7f160dfd0847185a43
https://pubmed.ncbi.nlm.nih.gov/17072891
https://pubmed.ncbi.nlm.nih.gov/17072891
Publikováno v:
Molecular Cell. 32:755-756
Summary In a recent issue of Cell , Pisareva et al. (2008) reveal that DHX29, a previously uncharacterized mammalian DExH-box protein, facilitates translation initiation on mRNAs with structured 5′ untranslated regions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d2cab70ee9d2b2334fc5851f2de632
https://doi.org/10.1016/j.molcel.2008.12.008
https://doi.org/10.1016/j.molcel.2008.12.008